diff --git a/README.md b/README.md
index 7cef940472ac2486ade30dd60bc98174ee480442..f70494e25bae56d17b44fbb01a034b8a2e4a3ce5 100644
--- a/README.md
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@@ -34,6 +34,13 @@ The files summary.py and similarityAllProteins.py provide the summary files of p
 
 Once every previous file is generated the code in Code statistical methods provide the graphics and statistical analysis as the ones shown in the publication.
 
+Analysis_of_similarities-patterns_significance__DR.ipynb stablishes the proposed drug repurposing analysis. 
+
+Analysis_of_similarities-patterns_significance__Simi_BLOSUM.ipynb, Analysis_of_similarities-patterns_significance__Simi_AA.ipynb and Analysis_of_similarities-patterns_significance__Simi_AA2.ipynb searches the similarities using the similarity matrixes previously computed for blosum, mod1(AA) and mod2(AA2). 
+
+The sandkeys are generated in Pattern found - Sankey plots.ipynb
+
+
 All Output will be directly generated inside the Output directory.