**Task Description**: Extract and list all terms from the “text to analyze” that can be classified into any of the categories listed in the “TUI code and Semantic type description text.” Classify each extracted term into one of these categories. **Instructions**: 1. **Extraction**: - Identify and extract all relevant terms from the “text to analyze” that relate to any condition or concept described in the “TUI code and Semantic type description text.” - Ensure that each term directly correlates with one of the provided categories. 2. **Classification**: - For each extracted term, determine the most appropriate category based on the descriptions and examples provided in the “TUI code and Semantic type description text.” - Assign the corresponding TUI code and Semantic Type to each term. 3. **Output Format**: - Present the extracted and classified terms in JSON format. - Ensure that each entity object contains the keys: "Entity", "TUI_Code", and "Semantic_Type." **Output Structure**: [ { "Entities": [ { "Entity": "Entity Name 1", "TUI_Code": "TUI Code 1", "Semantic_Type": "Semantic Type 1" }, { "Entity": "Entity Name 2", "TUI_Code": "TUI Code 2", "Semantic_Type": "Semantic Type 2" } ] } ] **Example**: Given the text to analyze: "Patient exhibits symptoms of fever and high blood glucose level due to Type 2 diabetes mellitus." - Extracted and classified terms: - "Fever" -> TUI Code: T033, Semantic Type: Finding - "High blood glucose level" -> TUI Code: T034, Semantic Type: Laboratory or Test Result - "Type 2 diabetes mellitus" -> TUI Code: T047, Semantic Type: Disease or Syndrome **Expected JSON Output**: [ { "Entities": [ { "Entity": "Fever", "TUI_Code": "T033", "Semantic_Type": "Finding" }, { "Entity": "High blood glucose level", "TUI_Code": "T034", "Semantic_Type": "Laboratory or Test Result" }, { "Entity": "Type 2 diabetes mellitus", "TUI_Code": "T047", "Semantic_Type": "Disease or Syndrome" } ] } ] **TUI code and Semantic type description text**: 1. **T019: Congenital Abnormality** - **Description**: Abnormal physical or functional conditions present at birth, often due to genetic or developmental factors. - **Examples**: Cleft lip and palate, Down syndrome (Trisomy 21), Congenital heart defects 2. **T020: Acquired Abnormality** - **Description**: Abnormal physical or functional conditions that develop after birth, typically as a result of environmental factors, injury, or disease. - **Examples**: Type 2 diabetes mellitus, Chronic obstructive pulmonary disease (COPD), Traumatic brain injury 3. **T033: Finding** - **Description**: Observable or measurable manifestations of a condition or disease, including symptoms, signs, and laboratory results. - **Examples**: Fever (symptom), Elevated blood pressure (sign), High blood glucose level (laboratory result) 4. **T034: Laboratory or Test Result** - **Description**: Specific findings obtained through laboratory tests or diagnostic procedures. - **Examples**: White blood cell count, Serum cholesterol level, Hemoglobin A1c level 5. **T041: Mental Process** - **Description**: Cognitive or psychological activities of the mind, such as perception, reasoning, or memory. - **Examples**: Decision-making, Problem-solving, Learning 6. **T046: Pathologic Function** - **Description**: Abnormal physiological or biological functions within the body, often associated with disease processes. - **Examples**: Impaired glucose metabolism, Altered blood flow, Dysregulated immune response 7. **T047: Disease or Syndrome** - **Description**: Pathological conditions characterized by a set of signs, symptoms, or clinical manifestations. - **Examples**: Hypertension, Diabetes mellitus, Asthma 8. **T048: Mental or Behavioral Dysfunction** - **Description**: Abnormalities or impairments in mental or behavioral functions, such as mood disorders, anxiety, or cognitive deficits. - **Examples**: Major depressive disorder, Generalized anxiety disorder, Attention-deficit/hyperactivity disorder (ADHD) 9. **T049: Cell or Molecular Dysfunction** - **Description**: Abnormalities or dysfunctions at the cellular or molecular level, including genetic mutations, metabolic disorders, or molecular signaling defects. - **Examples**: Mutation in the BRCA1 gene (associated with breast cancer), Deficiency of insulin production in type 1 diabetes mellitus, Dysregulation of neurotransmitter release in Parkinson's disease 10. **T050: Experimental Model of Disease** - **Description**: Experimental models of disease created in laboratory settings to simulate or study specific pathological conditions in biological systems. - **Examples**: Mouse model of Alzheimer's disease, Zebrafish model of heart failure, Cell culture model of cancer metastasis 11. **T059: Laboratory Procedure** - **Description**: Techniques or methods used in laboratory settings to analyze or study biological specimens, such as blood tests or tissue analyses. - **Examples**: Polymerase chain reaction (PCR), Enzyme-linked immunosorbent assay (ELISA), Western blotting 12. **T060: Diagnostic Procedure** - **Description**: Medical tests or examinations used to identify or confirm the presence of a disease or condition in a patient. - **Examples**: X-ray imaging, Magnetic resonance imaging (MRI), Electrocardiogram (ECG) 13. **T063: Molecular Biology Research Technique** - **Description**: Experimental techniques or methods used in molecular biology research, such as polymerase chain reaction (PCR) or gene sequencing. - **Examples**: CRISPR-Cas9 gene editing, RNA sequencing (RNA-seq), Chromatin immunoprecipitation (ChIP) 14. **T073: Manufactured Object** - **Description**: Tangible items produced or created through human manufacturing processes, such as medical devices or laboratory equipment. - **Examples**: Stethoscope, Microscope, Artificial joint prosthesis 15. **T170: Intellectual Product** - **Description**: Abstract or intangible creations of the human intellect, including scientific theories, algorithms, or research findings. - **Examples**: Newton's laws of motion, Theory of relativity, Computational model of protein folding 16. **T184: Sign or Symptom** - **Description**: Subjective or objective manifestations of a disease or condition experienced or observed by the patient or healthcare provider. - **Examples**: Headache, Rash, Cough 17. **T190: Anatomical Abnormality** - **Description**: Structural deviations or irregularities in the body's anatomy, including congenital malformations or acquired injuries. - **Examples**: Spina bifida, Fractured femur, Aortic aneurysm 18. **T191: Neoplastic Process** - **Description**: Abnormal growth or proliferation of cells leading to the formation of tumors or cancerous lesions. - **Examples**: Breast carcinoma, Lung adenocarcinoma, Melanoma 19. **T201: Clinical Attribute** - **Description**: Characteristics or properties associated with a disease or medical condition, including severity, duration, or response to treatment. - **Examples**: Severity of pain (mild, moderate, severe), Duration of symptoms (acute, chronic), Response to medication (improved, unchanged, worsened) **Text to Analyze**: