# ANALYSIS RESULTS

## Data summary 

| File                                                                                                                                                                                                                   | Nº columns | Nº rows | Description                                                                                                                                           |
|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|------------|---------|-------------------------------------------------------------------------------------------------------------------------------------------------------|
| [cell_type_summary_stats.tsv](https://medal.ctb.upm.es/internal/gitlab/disnet/network-medicine/network-medicine-and-single-cell-for-alzheimer/new/master/data/results/cell_type_summary_stats.tsv)                     | 10         | 9       | Contains the total number of DEGs, how many of them encoded known proteins, the number of these proteins included within the main Alzheimer's disease module, the cell-type-specific PPI subnetwork module size and its statistical significance by selecting node sets with the same degree distribution as the seed genes, repeating this process 1,000 times. A z-score was calculated, followed by a p-value and an FDR-corrected adjusted p-value.                                                                               |
| [network_analysis.csv](https://medal.ctb.upm.es/internal/gitlab/disnet/network-medicine/network-medicine-and-single-cell-for-alzheimer/new/master/data/results/network_analysis.csv)                                   | 12         | 3,240   | Contains all proteins belonging to at least one cell-type-specific PPI subnetwork, the corresponding Protein Accession Number, Gene Entrez ID, Gene Symbol, Cell type, logfoldchange of the corresponding DEGs, p-value, adjusted p-value, and the value of several network metrics (degree, betweenness centrality, closeness centrality, clustering coefficient, is hub) measured for the full interactome.         |
| [G_ppi_analysis.csv](https://medal.ctb.upm.es/internal/gitlab/disnet/network-medicine/network-medicine-and-single-cell-for-alzheimer/new/master/data/results/G_ppi_analysis.csv)                                       | 12         | 16,928  | Contains all the unique proteins present in the interactome and the calculated values of several network metrics (degree, betweenness centrality, closeness centrality, clustering coefficient, is hub) and a flag is_in_LCC which is True when the protein is present in the main Alzheimer's disease module.                              |