diff --git a/README.md b/README.md new file mode 100644 index 0000000000000000000000000000000000000000..99b0bc40edc23407a3bb8e5de527dc3fb9a54638 --- /dev/null +++ b/README.md @@ -0,0 +1,18 @@ +# Decoding cell-type-specific alterations in Alzheimer's disease through scRNA-seq and network analysis + +**Authors** + +Andrea Álvarez-Pérez, Lucía Prieto-Santamaría, Alejandro Rodríguez-González + +## Objective + +The present study examines whether gene expression patterns in Alzheimer's disease vary by cell type compared to healthy individuals. Using DEGs from scRNA-seq, we built cell-type-specific PPIs for eight major brain cell types. + +## Structure of the repository + +### Code +Scripts and jupyter notebooks employed to carry out this investigation. +### Data +Directory that contains the initial data used as the starting point for this study, as well as the intermediate files and the results generated during the analysis. +### Figures +Images obtained as a result of the research.