From 128f12dfc7fb4099f147843b651dcc83ab739b7f Mon Sep 17 00:00:00 2001 From: Maria Marin Date: Sat, 30 Mar 2024 18:04:57 +0000 Subject: [PATCH] Update README.md --- analysis/schizophrenia/README.md | 4 ++-- 1 file changed, 2 insertions(+), 2 deletions(-) diff --git a/analysis/schizophrenia/README.md b/analysis/schizophrenia/README.md index e02364a..60e6777 100644 --- a/analysis/schizophrenia/README.md +++ b/analysis/schizophrenia/README.md @@ -35,9 +35,9 @@ Identification of genes that may be potential therapeutic targets depending on w 2. Significantly **correlated** with the genes belonging to its **co-expression module** in different psyhiatric and neurological diseases (PNDs). 3. Part of disease module. -Data regarding the DGE and the co-expression modules were obtained, respectively, from the supplementary material of ... and ... +Data regarding the DGE and the co-expression modules were obtained, respectively, from the supplementary material of [Gandal et al. (2018)](10.1126/science.aad6469) and [Lüscher et al. (2020)](10.1038/s41398-020-0827-5) -## Criteria for identifying drug repurposing candidates: +### Identification of drug repurposing candidates 1. Distance to schizophrenia module between Q1 and median of distance values across treatment drugs. 2. Proximal to disease module (z-score of distance less than or equal to -0.15). -- 2.24.1