# Data
This directory contains the data referring to the nodes and links used to generate the studied networks.

## Nodes

| DATA | DESCRIPTION | IDENTIFIER | TOTAL | SOURCE |
|------------------|--------------------------- ----------------------------------|-------------- -------------------------------------------|------- -|-----------|
| Diseases (dis.tsv) | Data regarding diseases, including your name and identifier | Unified Medical Language System (UMLS) Concept Unique Identifiers (CUI) | 30,731 | UMLS |
| Genes (gen.tsv) | Data relating to genes, including their symbol and identifier | National Center of Biotechnology Information (NCBI) Identifiers | 20,610 | NCBI |
| Proteins (prot.tsv) | Data relating to proteins, including their identifier | Accession number in UniProt | 18,521 | UniProt |
| Drugs (dru.tsv) | Data relating to drugs, including your name and identifier | ChEMBL Identifier | 3,944 | ChEMBL |


## Links

| DATA | DESCRIPTION | IDENTIFIER | TOTAL | SOURCE |
|-----------------------|------------------------ -------------------------------------------------- ---------------|---------------------------------- --------------------|---------|------------------- -------------------------------------------------- ----|
| Disease – Drug (dis_dru_the.tsv) | Associations between diseases and drugs used for their treatment | UMLS CUI – ChEMBL Identifier | 52,179 | Comparative Toxicogenomics Database (CTD) |
| Disease – Gene (dis_gen.tsv) | Associations between diseases and genes whose mutation triggers the disease | UMLS CUI – NCBI Identifier | 358,209 | DisGeNET |
| Disease – Protein (dis_prot.tsv) | Associations between diseases and proteins produced from their pathological genes | UMLS CUI – Accession number in UniProt | 361,325 | DisGeNET |
| Gene – Protein (gen_pro.tsv) | Associations between genes and proteins produced from the gene | NCBI Identifier – Accession Number in UniProt | 15,770 | DisGeNET |
| Protein – Protein (pro_pro.tsv) | Associations between proteins that physically interact with each other | Accession number in UniProt – Accession number in UniProt | 439,863 | DisGeNET |
| Drug – Protein (dru_pro.tsv) | Associations between drugs and the target proteins they affect | ChEMBL identifier – Accession number in UniProt | 5,946 | ChEMBL and DrugBank |
| Disease – Symptom (dse_sym.tsv) | Associations between diseases and the symptoms they develop | UMLS CUI – UMLS Concept Unique Identifiers | 318,550 | ChEMBL and (Side Effect Resource) SIDER |