").append( jQuery.parseHTML( responseText ) ).find( selector ) :
-
- // Otherwise use the full result
- responseText );
-
- }).complete( callback && function( jqXHR, status ) {
- self.each( callback, response || [ jqXHR.responseText, status, jqXHR ] );
- });
- }
-
- return this;
-};
-
-
-
-
-jQuery.expr.filters.animated = function( elem ) {
- return jQuery.grep(jQuery.timers, function( fn ) {
- return elem === fn.elem;
- }).length;
-};
-
-
-
-
-
-var docElem = window.document.documentElement;
-
-/**
- * Gets a window from an element
- */
-function getWindow( elem ) {
- return jQuery.isWindow( elem ) ?
- elem :
- elem.nodeType === 9 ?
- elem.defaultView || elem.parentWindow :
- false;
-}
-
-jQuery.offset = {
- setOffset: function( elem, options, i ) {
- var curPosition, curLeft, curCSSTop, curTop, curOffset, curCSSLeft, calculatePosition,
- position = jQuery.css( elem, "position" ),
- curElem = jQuery( elem ),
- props = {};
-
- // set position first, in-case top/left are set even on static elem
- if ( position === "static" ) {
- elem.style.position = "relative";
- }
-
- curOffset = curElem.offset();
- curCSSTop = jQuery.css( elem, "top" );
- curCSSLeft = jQuery.css( elem, "left" );
- calculatePosition = ( position === "absolute" || position === "fixed" ) &&
- jQuery.inArray("auto", [ curCSSTop, curCSSLeft ] ) > -1;
-
- // need to be able to calculate position if either top or left is auto and position is either absolute or fixed
- if ( calculatePosition ) {
- curPosition = curElem.position();
- curTop = curPosition.top;
- curLeft = curPosition.left;
- } else {
- curTop = parseFloat( curCSSTop ) || 0;
- curLeft = parseFloat( curCSSLeft ) || 0;
- }
-
- if ( jQuery.isFunction( options ) ) {
- options = options.call( elem, i, curOffset );
- }
-
- if ( options.top != null ) {
- props.top = ( options.top - curOffset.top ) + curTop;
- }
- if ( options.left != null ) {
- props.left = ( options.left - curOffset.left ) + curLeft;
- }
-
- if ( "using" in options ) {
- options.using.call( elem, props );
- } else {
- curElem.css( props );
- }
- }
-};
-
-jQuery.fn.extend({
- offset: function( options ) {
- if ( arguments.length ) {
- return options === undefined ?
- this :
- this.each(function( i ) {
- jQuery.offset.setOffset( this, options, i );
- });
- }
-
- var docElem, win,
- box = { top: 0, left: 0 },
- elem = this[ 0 ],
- doc = elem && elem.ownerDocument;
-
- if ( !doc ) {
- return;
- }
-
- docElem = doc.documentElement;
-
- // Make sure it's not a disconnected DOM node
- if ( !jQuery.contains( docElem, elem ) ) {
- return box;
- }
-
- // If we don't have gBCR, just use 0,0 rather than error
- // BlackBerry 5, iOS 3 (original iPhone)
- if ( typeof elem.getBoundingClientRect !== strundefined ) {
- box = elem.getBoundingClientRect();
- }
- win = getWindow( doc );
- return {
- top: box.top + ( win.pageYOffset || docElem.scrollTop ) - ( docElem.clientTop || 0 ),
- left: box.left + ( win.pageXOffset || docElem.scrollLeft ) - ( docElem.clientLeft || 0 )
- };
- },
-
- position: function() {
- if ( !this[ 0 ] ) {
- return;
- }
-
- var offsetParent, offset,
- parentOffset = { top: 0, left: 0 },
- elem = this[ 0 ];
-
- // fixed elements are offset from window (parentOffset = {top:0, left: 0}, because it is its only offset parent
- if ( jQuery.css( elem, "position" ) === "fixed" ) {
- // we assume that getBoundingClientRect is available when computed position is fixed
- offset = elem.getBoundingClientRect();
- } else {
- // Get *real* offsetParent
- offsetParent = this.offsetParent();
-
- // Get correct offsets
- offset = this.offset();
- if ( !jQuery.nodeName( offsetParent[ 0 ], "html" ) ) {
- parentOffset = offsetParent.offset();
- }
-
- // Add offsetParent borders
- parentOffset.top += jQuery.css( offsetParent[ 0 ], "borderTopWidth", true );
- parentOffset.left += jQuery.css( offsetParent[ 0 ], "borderLeftWidth", true );
- }
-
- // Subtract parent offsets and element margins
- // note: when an element has margin: auto the offsetLeft and marginLeft
- // are the same in Safari causing offset.left to incorrectly be 0
- return {
- top: offset.top - parentOffset.top - jQuery.css( elem, "marginTop", true ),
- left: offset.left - parentOffset.left - jQuery.css( elem, "marginLeft", true)
- };
- },
-
- offsetParent: function() {
- return this.map(function() {
- var offsetParent = this.offsetParent || docElem;
-
- while ( offsetParent && ( !jQuery.nodeName( offsetParent, "html" ) && jQuery.css( offsetParent, "position" ) === "static" ) ) {
- offsetParent = offsetParent.offsetParent;
- }
- return offsetParent || docElem;
- });
- }
-});
-
-// Create scrollLeft and scrollTop methods
-jQuery.each( { scrollLeft: "pageXOffset", scrollTop: "pageYOffset" }, function( method, prop ) {
- var top = /Y/.test( prop );
-
- jQuery.fn[ method ] = function( val ) {
- return access( this, function( elem, method, val ) {
- var win = getWindow( elem );
-
- if ( val === undefined ) {
- return win ? (prop in win) ? win[ prop ] :
- win.document.documentElement[ method ] :
- elem[ method ];
- }
-
- if ( win ) {
- win.scrollTo(
- !top ? val : jQuery( win ).scrollLeft(),
- top ? val : jQuery( win ).scrollTop()
- );
-
- } else {
- elem[ method ] = val;
- }
- }, method, val, arguments.length, null );
- };
-});
-
-// Add the top/left cssHooks using jQuery.fn.position
-// Webkit bug: https://bugs.webkit.org/show_bug.cgi?id=29084
-// getComputedStyle returns percent when specified for top/left/bottom/right
-// rather than make the css module depend on the offset module, we just check for it here
-jQuery.each( [ "top", "left" ], function( i, prop ) {
- jQuery.cssHooks[ prop ] = addGetHookIf( support.pixelPosition,
- function( elem, computed ) {
- if ( computed ) {
- computed = curCSS( elem, prop );
- // if curCSS returns percentage, fallback to offset
- return rnumnonpx.test( computed ) ?
- jQuery( elem ).position()[ prop ] + "px" :
- computed;
- }
- }
- );
-});
-
-
-// Create innerHeight, innerWidth, height, width, outerHeight and outerWidth methods
-jQuery.each( { Height: "height", Width: "width" }, function( name, type ) {
- jQuery.each( { padding: "inner" + name, content: type, "": "outer" + name }, function( defaultExtra, funcName ) {
- // margin is only for outerHeight, outerWidth
- jQuery.fn[ funcName ] = function( margin, value ) {
- var chainable = arguments.length && ( defaultExtra || typeof margin !== "boolean" ),
- extra = defaultExtra || ( margin === true || value === true ? "margin" : "border" );
-
- return access( this, function( elem, type, value ) {
- var doc;
-
- if ( jQuery.isWindow( elem ) ) {
- // As of 5/8/2012 this will yield incorrect results for Mobile Safari, but there
- // isn't a whole lot we can do. See pull request at this URL for discussion:
- // https://github.com/jquery/jquery/pull/764
- return elem.document.documentElement[ "client" + name ];
- }
-
- // Get document width or height
- if ( elem.nodeType === 9 ) {
- doc = elem.documentElement;
-
- // Either scroll[Width/Height] or offset[Width/Height] or client[Width/Height], whichever is greatest
- // unfortunately, this causes bug #3838 in IE6/8 only, but there is currently no good, small way to fix it.
- return Math.max(
- elem.body[ "scroll" + name ], doc[ "scroll" + name ],
- elem.body[ "offset" + name ], doc[ "offset" + name ],
- doc[ "client" + name ]
- );
- }
-
- return value === undefined ?
- // Get width or height on the element, requesting but not forcing parseFloat
- jQuery.css( elem, type, extra ) :
-
- // Set width or height on the element
- jQuery.style( elem, type, value, extra );
- }, type, chainable ? margin : undefined, chainable, null );
- };
- });
-});
-
-
-// The number of elements contained in the matched element set
-jQuery.fn.size = function() {
- return this.length;
-};
-
-jQuery.fn.andSelf = jQuery.fn.addBack;
-
-
-
-
-// Register as a named AMD module, since jQuery can be concatenated with other
-// files that may use define, but not via a proper concatenation script that
-// understands anonymous AMD modules. A named AMD is safest and most robust
-// way to register. Lowercase jquery is used because AMD module names are
-// derived from file names, and jQuery is normally delivered in a lowercase
-// file name. Do this after creating the global so that if an AMD module wants
-// to call noConflict to hide this version of jQuery, it will work.
-if ( typeof define === "function" && define.amd ) {
- define( "jquery", [], function() {
- return jQuery;
- });
-}
-
-
-
-
-var
- // Map over jQuery in case of overwrite
- _jQuery = window.jQuery,
-
- // Map over the $ in case of overwrite
- _$ = window.$;
-
-jQuery.noConflict = function( deep ) {
- if ( window.$ === jQuery ) {
- window.$ = _$;
- }
-
- if ( deep && window.jQuery === jQuery ) {
- window.jQuery = _jQuery;
- }
-
- return jQuery;
-};
-
-// Expose jQuery and $ identifiers, even in
-// AMD (#7102#comment:10, https://github.com/jquery/jquery/pull/557)
-// and CommonJS for browser emulators (#13566)
-if ( typeof noGlobal === strundefined ) {
- window.jQuery = window.$ = jQuery;
-}
-
-
-
-
-return jQuery;
-
-}));
diff --git a/SEM-DISNET Documentacion/OOPSevaluation/evaluation/jquery.tablesorter.min.js b/SEM-DISNET Documentacion/OOPSevaluation/evaluation/jquery.tablesorter.min.js
deleted file mode 100644
index b8605df1e7277e2f88237eb7bee7c7e38d80a232..0000000000000000000000000000000000000000
--- a/SEM-DISNET Documentacion/OOPSevaluation/evaluation/jquery.tablesorter.min.js
+++ /dev/null
@@ -1,4 +0,0 @@
-
-(function($){$.extend({tablesorter:new
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-
-
-
- SEM-DISNET
-
-
-
-
-
-
-
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-
-- Title
-- SEM-DISNET
-- URI
-- http://w3id.org/eboca/sem-disnet
-- Version
-
-
The following evaluation results have been generated by the RESTFul web service provided by OOPS! (OntOlogy Pitfall Scanner!).
-
It is obvious that not all the pitfalls are equally important; their impact in the ontology will depend on multiple factors. For this reason, each pitfall has an importance level attached indicating how important it is. We have identified three levels:
-
-
-- Critical
-- It is crucial to correct the pitfall. Otherwise, it could affect the ontology consistency, reasoning, applicability, etc.
-
-- Important
- Though not critical for ontology function, it is important to correct this type of pitfall.
-
-- Minor
- It is not really a problem, but by correcting it we will make the ontology nicer.
-
Evaluation results
-
-
-
-
-
-
Ontology elements (classes, object properties and datatype properties) are created isolated, with no relation to the rest of the ontology.
This pitfall affects to the following ontology elements:
-
-
-
-
-
-
-
This pitfall consists in creating an ontology element and failing to provide human readable annotations attached to it. Consequently, ontology elements lack annotation properties that label them (e.g. rdfs:label, lemon:LexicalEntry, skos:prefLabel or skos:altLabel) or that define them (e.g. rdfs:comment or dc:description). This pitfall is related to the guidelines provided in [5].
This pitfall affects to the following ontology elements:
-
-
-
-
-
-
-
Object and/or datatype properties without domain or range (or none of them) are included in the ontology.
This pitfall affects to the following ontology elements:
-
-
-
-
-
-
-
This pitfall appears when any relationship (except for those that are defined as symmetric properties using owl:SymmetricProperty) does not have an inverse relationship (owl:inverseOf) defined within the ontology.
This pitfall affects to the following ontology elements:
-
-
-
-
-
-
-
The ontology elements are not named following the same convention (for example CamelCase or use of delimiters as "-" or "_") . Some notions about naming conventions are provided in [2].
*This pitfall applies to the ontology in general instead of specific elements
-
-
-
-
References:
-
--
- [1] Aguado-De Cea, G., Montiel-Ponsoda, E., Poveda-Villalón, M., and Giraldo-Pasmin, O.X. (2015). Lexicalizing Ontologies: The issues behind the labels. In Multimodal communication in the 21st century: Professional and academic challenges. 33rd Conference of the Spanish Association of Applied Linguistics (AESLA), XXXIII AESLA.
--
- [2] Noy, N. F., McGuinness, D. L., et al. (2001). Ontology development 101: A guide to creating your first ontology.
--
- [3] Gómez-Pérez, A. (1999). Evaluation of Taxonomic Knowledge in Ontologies and Knowledge Bases. Proceedings of the Banff Knowledge Acquisition for Knowledge-Based Systems Workshop. Alberta, Canada.
--
- [4] Montiel-Ponsoda, E., Vila Suero, D., Villazón-Terrazas, B., Dunsire, G., Escolano RodrÃguez, E., Gómez-Pérez, A. (2011). Style guidelines for naming and labeling ontologies in the multilingual web.
--
- [5] Vrandecic, D. (2010). Ontology Evaluation. PhD thesis.
--
- [6] Gómez-Pérez, A. (2004). Ontology evaluation. In Handbook on ontologies, pages 251-273. Springer.
--
- [7] Rector, A., Drummond, N., Horridge, M., Rogers, J., Knublauch, H., Stevens, R., Wang, H., and Wroe, C. (2004). Owl pizzas: Practical experience of teaching owl-dl: Common errors & common patterns. In Engineering Knowledge in the Age of the Semantic Web, pages 63-81. Springer.
--
- [8] Hogan, A., Harth, A., Passant, A., Decker, S., and Polleres, A. (2010). Weaving the pedantic web. In Proceedings of the WWW2010 Workshop on Linked Data on the Web, LDOW 2010, Raleigh, USA, April 27, 2010.
--
- [9] Archer, P., Goedertier, S., and Loutas, N. (2012). D7. 1.3-study on persistent URIs, with identification of best practices and recommendations on the topic for the Mss and the EC. PwC EU Services.
--
- [10] Bernes-Lee Tim. (2006). “Linked Data - Design issuesâ€. http://www.w3.org/DesignIssues/LinkedData.html
--
- [11] Heath, T. and Bizer, C. (2011). Linked Data: Evolving the Web into a Global Data Space. Morgan & Claypool, 1st edition.
--
- [12] Vatant, B. (2012). Is your linked data vocabulary 5-star?. http://bvatant.blogspot.fr/2012/02/is-your-linked-data-vocabulary-5-star_9588.html
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SEM-DISNET
-
Release 2022-03-30
-
-
-
- - Contributors:
- - Andrea Ãlvarez Pérez (MEDAL)
- - Ana Iglesias Molina (OEG)
- - LucÃa Prieto SantamarÃa (MEDAL)
- - Alejandro RodrÃguez González (MEDAL)
-
- - Publisher:
- - Medical Data Analytics Laboratory (MEDAL): https://medal.ctb.upm.es/
- - Ontology Engineering Group (OEG): https://oeg.fi.upm.es/
-
- - Download serialization:
- License:
-
-
-
Provenance of this page
-
-
-
- Ontology Specification Draft
-
-
-
-
-
-
Introduction back to ToC
-
-SEM-DISNET ontology provides a integrated ontology used to describe the defined entities
- which appear in the DISNET database. It is an ontology aimed at facilitating the analysis
- of biomedical data, allowing the discovery of new patterns and associations between genes,
- drugs and their targets to be applied in cases of drug repositioning.
-
- This project has been carried out within the DISNET project of MEDAL Laboratory (Medical
- Data Analytics) at the CTB-UPM, together with DRUGS4COVID, developed by the OEG-UPM (Ontology
- Engineering Group).
-
-
-
Namespace declarations
-
-
- Table 1: Namespaces used in the document
-
-| sem-disnet | <http://w3id.org/eboca/sem-disnet> |
-| metadata | <http://data.bioontology.org/metadata> |
-| EVS | <http://ncicb.nci.nih.gov/xml/owl/EVS> |
-| owl | <http://www.w3.org/2002/07/owl> |
-| xsd | <http://www.w3.org/2001/XMLSchema> |
-| skos | <http://www.w3.org/2004/02/skos/core> |
-| rdfs | <http://www.w3.org/2000/01/rdf-schema> |
-| ORDO | <http://www.orpha.net/ORDO> |
-| ctd_vocabulary | <http://bio2rdf.org/ctd_vocabulary:> |
-| chembl | <http://rdf.ebi.ac.uk/terms/chembl> |
-| terms | <http://purl.org/dc/terms> |
-| Thesaurus | <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl> |
-| xml | <http://www.w3.org/XML/1998/namespace> |
-| bio2rdf_vocabulary | <http://bio2rdf.org/bio2rdf_vocabulary:> |
-| wp | <http://vocabularies.wikipathways.org/wp> |
-| SNOMEDCT | <http://purl.bioontology.org/ontology/SNOMEDCT> |
-| vann | <http://purl.org/vocab/vann> |
-| dto | <http://www.drugtargetontology.org/dto> |
-| foaf | <http://xmlns.com/foaf/0.1> |
-| void | <http://rdfs.org/ns/void> |
-| umlssn | <http://biotop.googlecode.com/svn/trunk/umlssn.owl> |
-| oboInOwl | <http://www.geneontology.org/formats/oboInOwl> |
-| resource | <http://semanticscience.org/resource> |
-| protege | <http://protege.stanford.edu/plugins/owl/protege> |
-| efo | <http://www.ebi.ac.uk/efo> |
-| rdf | <http://www.w3.org/1999/02/22-rdf-syntax-ns> |
-| obo | <http://purl.obolibrary.org/obo> |
-| dc | <http://purl.org/dc/elements/1.1> |
-
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SEM-DISNET: Overview back to ToC
-
-This ontology has the following classes and properties.
-
Classes
-
Object Properties
Data Properties
-
-
-
-
-
SEM-DISNET: Description back to ToC
-
Figure 1 provides a general overview of SEM-DISNET Ontology. For the sake of clarity and understanding, the diagram
- was designed including in each of the boxes, the DISNET label (disnet:disnetLabel associated with each class, along with the class
- identifier (dcterms:identifier of the original ontology, including its namespace. For this reason, the following text will refer to
- the classes using these attributes, although all classes are by defect described by their original label (rdfs:label).
-
-
- 
Figure 1 - SEM-DISNET schema for the representation of DISNET data.
-
-
-
SEM-DISNET Ontology is built mostly from the reuse of existing ontology concepts. Mainly, it is based on the
- ontology developed by DisGeNET (DisGeNET-RDF), one of the main sources used by DISNET. Other important reused
- concepts or Classes were taken from National Cancer Institute thesaurus (NCIT), Semanticscience Integrated Ontology (SIO),
- CHEMBL, SNOMED, Comparative Toxicogenomics Database (CTD), Orphanet Rare Disease Ontology (ORDO) and WikiPathways.
- It also reuses Object Propeties from NCIT and SIO ontologies.
-
-
The ontology schema is organized around the central classes Disease and Drug.
-
-
Disease class This class was taken from NCIT and represents a condition that is relevant to human
- neoplasms and non-neoplasms disorders. It is specified the Semantic Type (disgenet:UMLS Semantic Type),
- the Disease class it belongs (obo:Disease class) and the marker it can be associated with (ncit:
- Disease Marker), including the type of sample (disnet:sample) and the marker concentration (disnet:
- concentration). Disease references (sio:'is referred to by') to classes which represent
- relationships between concepts:
-
- - Association between a Disease and a ncRNA: although the association class was designed
- de novo by DISNET (disnet:Disease ncRNA Association), ncRNA class was taken from NCIT (ncit:ncRNA).
- Also, attributes as the ncRNA category, which refers to the classification according to HMDD (Human microRNA Disease
- Database) and LncRNADisease database (disnet:category), the ncRNA effect in the organism (disnet:type)
- and the causality (disnet:causality) are given.
- - Association between a Disease and rare diseases: this module was entirely reused from Orphanet
- database. In this case, Disease is directly related to rare disease class (ordo:Orpha), and the association class
- (ordo:Prevalence) associates the rare disease with its annual incidence (ordo:Prevalence class)
- specifying the geographical location (disnet:geo).
- - Association between a Disease and a Variant: the association (disnet:Variant Disease Association)
- has an associated score (sio:'has measurement value') defined by the ncit:Score class. Variants (obo:Variant)
- are resources defined by attributes such as chromosome number (ncit:Chromosome), position (ncit:Chromosome position)
- and other parameters (disgenet:Disease specificity and disgenet: Disease pleiotropy)
- - Association between a Disease and a Gene: the same way as with variants, the association is defined
- by a score (ncit:Score). Gene class (ncit:Gene) attributes embraces the corresponding symbol
- (ncit:Gene Symbol), the metabolic pathway(s) to which it belongs (wp:Pathway), class reused from WikiPathways,
- and other parameters (disgenet:Disease specificity and disgenet: Disease pleiotropy). Other properties
- attributed to Gene entity include the sequence (disnet:geneSequence), the strand (disnet:strand),
- sequence start (disnet:seqStart) and end (disnet:seqEnd) positions, and the chromosome version
- (disnet:chrVersion).
- Gene class encodes (sio:'encondes') certain Protein (ncit:Protein) whose sequence is present
- as an attribute (cco:proteinSequence) reused from ChEMBL ontology. Each protein also belongs to a class
- (obo:Protein class) and participates (sio:'is participant in') in protein-protein interactions
- (ncit:PPI). Furthermore, both Protein and Gene classes are present in Organisms (ncit:Organism),
- and either Organism and Protein are can act as a target (sio:'is target in', being related to Target class
- (cco:Target).
- - Association between a Disease and a Phenotype: this association and the related class Phenotype
- (disnet:Phenotype) have been modelled de novo, since no existing classes were found in other
- ontologies with the meaning corresponding to the one in DISNET database. The phenotype refers to the
- observable and detectable signs in a patient due to the effects caused by a Disease or a Drug causing changes in
- their original appearence. Therefore, this class is also connected to Drug class in more than one way (explained
- below). Phenotypes are also associated with a specific Semantic Type (disgenet:UMLS Semantic Type)
-
-
-
- The association between both central classes, Disease and Drug was reused from the CTD, the main
- source from which the information stored in the DISNET database is obtained. However, this class has (owl:sameAs)
- an associated class in SIO (sio:'chemical-disease association'). In addition, this association has been
- modelled de novo with two subclasses emerging from it. Drug-disease pairs are classified into these subclasses
- depending on the effect the drug has on the disease. A chemical that correlates with a disease or may play a role in
- the etiology of a disease, acting as a marker of those diseases (disnet:Drug Disease Marker) or it can be used
- to treat the disease, having a known or potential therapeutic effect on it (disnet:Drug Disease Therapeutic).
- Additionally, the association is identified by an inferred score established by CTD-curated chemical-gene interactions
- (sio:'has value').
-
-
Drug class This class (cco:Drug) was reused from ChEMBL database and represents, according to
- the Chemical Entities of Biological Interest (ChEBI), any substance which when absorbed into a living organism may modify
- one or more of its functions. The information housed in DISNET was integrated from different sources, as DrugBank, RXCUI and
- DisGeNET. Other de novo properties associated with Drug concept include the chemical structure (disnet:chemicalStructure),
- the inchi Key (disnet:inchiKey) and synonymous names for the drugs (disnet:synonymous). The ATC
- classification (cco:atcClassification) and the substance (or molecular) type (cco:substanceType)
- attributes were taken from ChEML ontolgy. Moreover, it references (sio:'is referred to by') to classes which
- represent relationships between drugs and other entities:
-
- - Association between a Drug and a Target: this relationship (cco:Drug Target Association)
- is also known as the mechanism of action of the drug when it addresses to the Target (cco:Target), a molecule
- in the body, usually a protein, that is intrinsically associated with a particular disease to which is directed the drug. Target class has correspondence
- (owl:sameAs) with Drug Target Ontology (DTO) dto:drug target too, and its type is defined by ChEMBL
- attribute cco:targetType. Mechanism class data was taken from ChEMBL and DrugBank databases (skos:exactMatch)
- , corresponds with DTO dto:drug target role class (owl:sameAs) and is defined by the attribute
- cco:mechanismActionType which belongs to ChEMBL ontology.
- - Association between a Drug and a Phenotype: the relationship between a drug and a phenotype can
- be defined according to several criteria. For this reason, both classes (cco:Drug and disnet:Phenotype)
- are connected by three association classes, each of them refering to a possible causality of the interaction between
- a drug and a phenotype:
-
-
- Drug Phenotype Indication: indication is the term for the approved uses of a medication. In
- other words, indicates the relationship of the desirable measurable effects that cause changes in a patient's phenotype
- and the response to treatment with a drug which is indicated to treat them. This relationship (cco:Drug
- Phenotype Indication) can be classified due to the highest development phase at which that indication has been
- investigated (cco:highestDevelopmentPhase).
- - Drug Phenotype Side Effect: describes the association between symptoms considered as
- adverse effects that cause patient phenotype changes in response to the treatment with a drug. This class was resued
- from SNOMED CT database (sct:Drug Phenotype Side Effect) although the data stored in DISNET database is
- integrated from SIDER, and also includes the highest development phase ChEMBL attribute (cco:highestDevelopmentPhase).
- In this case, the Object Properties which relate this association class with Drug and Phenotype were created
- de novo and classified as subproperties of the original ones taken from ChEMBL and the main SIO properties
- (sio:'refers to' and sio:'is referred to by') that are used all over the ontology. This approach
- is specified in the boxes above the diagram, so highlighted Object Properties are subproperties of SIO and another
- reused ontology.
- - Drug Drug Interaction: is an interaction in which two drugs interact in such a way to
- produce a non-additive biological response (sio:DDI). The ain source (skos:exactMatch) is
- DrugBank. However, TWOSIDES provides the information about the potential adverse side effects that the DDI causes
- in a phenotype, and it is related to Phenotype class by two de novo Object Properties (disnet:isSideEffect
- and disnet:hasSideEffect). Furthermore, drug participate (sio:'is participant in') drug-drug
- interactions.
-
-
-
-
-
-
-
The classes corresponding to the associations between concepts were incorporated into a class hierarchy, represented as
- a tree independently of the main diagram for the sake of clarity, since hierarchical relationships facilitates data integration.
- All Association classes represented in the diagram are subclasses of the central SIO class sio:Association.
-
-
Example: Gene Disease Association is directly reuses from SIO as a subclass of Association, but the
- association between a drug and a target suits better with ChEMBL's ChEMBL Mechanism Class. The strategy consisted in
- creating a new DISNET class Drug Target Association, classified as a subclass of ChEMBL and SIO.
-
-
In the case of the Object Properties, the objective was to make the relationships between the entities as homogeneous
- as possible, so, as far as possible, an attempt was made to reuse the Object Properties of SIO or, in default, NCIT.
- However, in cases where an Object Property was not found in these ontologies with the meaning given by DISNET, an
- Object Property was created de novo under DISNET's namespace and classified as a subclass of the relation of
- the other ontology with which its meaning corresponded and as a subclass of one of the two main Object Properties of SIO,
- sio:'refers to' or sio:'is referred to by'.
-
-
Example: the core class Drug uses ChEMBL's Object Property cco:hasMechanism to relate to the
- Drug Target Association (range) class, but uses SNOMED's Object Property sct:causative_agent_of in the
- relationship with Drug Phenotype Side Effect class (range). In order for the relationships to be homogeneous,
- the intermediate classes disnet:drugForMechanism and disnet:drugForSideEffect were created de novo
- and classified as subclasses of those of ChEMBL and SNOMED and of sio:'is referred to by'.
-
-
-
-
-
-
Cross-reference for SEM-DISNET classes, object properties and data properties back to ToC
-This section provides details for each class and property defined by SEM-DISNET.
-
-
Classes
-
-
-
A CTD association between a chemical and a disease [ctd_vocabulary:Chemical-Disease-Association]c
- back to ToC or Class ToC
-
-
-
- IRI: http://bio2rdf.org/ctd_vocabulary:Chemical-Disease-Association
-
- - has sub-classes
- -
- Drug-Disease Association
- c
-
-
-
-
-
-
-
-
-
annual incidencec
- back to ToC or Class ToC
-
-
-
- IRI: http://www.orpha.net/ORDO/Orphanet_409967
-
-
-
associationc
- back to ToC or Class ToC
-
-
-
- IRI: http://semanticscience.org/resource/SIO_000897
-
- - Is defined by
- -
- http://semanticscience.org/ontology/sio.owl
-
-
-
- - has sub-classes
- -
- Disease-Phenotype Association
- c, Disease-Variant Association
- c, Disease-ncRNA Association
- c, Drug-Disease Association
- c, Drug-Phenotype Indication
- c, Drug-Phenotype Side Effect
- c, Drug-Target Association
- c, Prevalence
- c, Protein-Protein Interaction
- c, drug drug interaction
- c, gene-disease association
- c
-
- - is disjoint with
- -
- gene-disease association
- c, Disease-ncRNA Association
- c, Drug-Disease Association
- c
-
-
-
-
-
-
-
-
-
-
-
ChEMBL Substance Classc
- back to ToC or Class ToC
-
-
-
ChEMBL Substance Classc
- back to ToC or Class ToC
-
-
-
- IRI: http://rdf.ebi.ac.uk/terms/chembl#Substance
-
- - is in domain of
- -
- ATC Code ATC Code
- dp, ChEMBL Substance Entity Type ChEMBL Substance Entity Type
- dp, Chemical Structure
- dp, Drug For Drug-Phenotype Indication
- op, Drug For Drug-Phenotype Side Effect
- op, Drug For Drug-Target Association
- op, Inchi Key
- dp, Synonymous
- dp
-
- - is in range of
- -
- Drug-Target Association Has Drug
- op, Indication Has Drug
- op, Side Effect Has Drug
- op
-
- - is disjoint with
- -
- Disease, Disorder or Finding
- c, ChEMBL Target Class ChEMBL Target Class
- c, Phenotype
- c
-
-
-
-
-
-
-
-
-
conceptc
- back to ToC or Class ToC
-
-
-
- IRI: http://semanticscience.org/resource/SIO_000326
-
- - Is defined by
- -
- http://semanticscience.org/ontology/sio.owl
-
-
-
- - has sub-classes
- -
- Acquired Abnormality [umls:T020]
- c, Amino Acid, Peptide, or Protein [umls:T116]
- c, Anatomical Abnormality [umls:T190]
- c, Body Substance [umls:T031]
- c, Cell Component [umls:T026]
- c, Cell Function [umls:T043]
- c, Cell or Molecular Dysfunction [umls:T049]
- c, Classification [umls:T185]
- c, Clinical Attribute [umls:T201]
- c, Congenital Abnormality [umls:T019]
- c, Diagnostic Procedure [umls:T060]
- c, Disease or Syndrome [umls:T047]
- c, Experimental Model of Disease [umls:T050]
- c, Finding [umls:T033]
- c, Immunologic Factor [umls:T129]
- c, Individual Behavior [umls:T055]
- c, Injury or Poisoning [umls:T037]
- c, Laboratory Procedure [umls:T059]
- c, Laboratory or Test Result [umls:T034]
- c, Mental Process [umls:T041]
- c, Mental or Behavioral Dysfunction [umls:T048]
- c, Molecular Function [umls:T044]
- c, Neoplastic Process [umls:T191]
- c, Organ or Tissue Function [umls:T042]
- c, Organism Attribute [umls:T032]
- c, Organism Function [umls:T040]
- c, Pathologic Function [umls:T046]
- c, Physiologic Function [umls:T039]
- c, Sign or Symptom [umls:T184]
- c, Social Behavior [umls:T054]
- c, Temporal Concept [umls:T079]
- c
-
-
-
-
-
-
d t o 00102000c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_00102000
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 01300327c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_01300327
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 02300001c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_02300001
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 03300101c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_03300101
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 05007378c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_05007378
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 05007405c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_05007405
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 05007527c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_05007527
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 05007530c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_05007530
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 05007542c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_05007542
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 05007557c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_05007557
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 05007575c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_05007575
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 05007584c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_05007584
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 05007599c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_05007599
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 05007608c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_05007608
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 05007612c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_05007612
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 05007613c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_05007613
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 05007616c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_05007616
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 05007620c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_05007620
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 05007621c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_05007621
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 05007624c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_05007624
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
d t o 05007697c
- back to ToC or Class ToC
-
-
-
- IRI: http://www.drugtargetontology.org/dto/DTO_05007697
-
-
- - has super-classes
- -
- ProteinClass
- c
-
-
-
-
-
-
Disease Markerc
- back to ToC or Class ToC
-
-
-
- IRI: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18329
-
- - is in domain of
- -
- Concentration
- dp, Sample
- dp
-
-
-
-
-
-
-
-
Disease-Phenotype Associationc
- back to ToC or Class ToC
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#DiseasePhenotype
-
-
- - has super-classes
- -
- association
- c
-
-
-
-
-
Disease-Variant Associationc
- back to ToC or Class ToC
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#DiseaseVariant
-
-
- - has super-classes
- -
- association
- c
-
-
-
-
-
-
-
Drug Disease Inferredc
- back to ToC or Class ToC
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#DrugDiseaseInferred
-
-
- - has super-classes
- -
- Drug-Disease Association
- c
-
-
-
-
-
-
Drug Disease Therapeuticc
- back to ToC or Class ToC
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#DrugDiseaseTherapeutic
-
-
- - has super-classes
- -
- Drug-Disease Association
- c
-
-
-
-
-
-
-
-
-
-
-
-
-
- IRI: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16612
-
- - is in domain of
- -
- Chromosome No Version
- dp, Gene Sequence
- dp, Gene_Found_In_Organism
- op, Gene_Mutant_Encodes_Gene_Product_Sequence_Variation
- op, Sequence end position
- dp, Sequence start position
- dp, Strand
- dp, encodes
- op, is represented by
- op
-
- - is in range of
- -
- is associated with
- op, is encoded by
- op, represents
- op
-
- - is disjoint with
- -
- Score
- c, Disease, Disorder or Finding
- c
-
-
-
-
-
Gene Symbolc
- back to ToC or Class ToC
-
-
-
- IRI: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43568
-
- - is in domain of
- -
- represents
- op
-
- - is in range of
- -
- is represented by
- op
-
-
-
-
-
-
geographyc
- back to ToC or Class ToC
-
-
-
- IRI: http://www.orpha.net/ORDO/Orphanet_C009
-
- - has sub-classes
- -
- Prevalence
- c
-
-
-
-
-
group of disordersc
- back to ToC or Class ToC
-
-
-
- IRI: http://www.orpha.net/ORDO/Orphanet_557492
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Pathwayc
- back to ToC or Class ToC
-
-
-
- IRI: http://vocabularies.wikipathways.org/wp#Pathway
-
-
-
-
-
Phenotypic abnormalityc
- back to ToC or Class ToC
-
-
-
- IRI: http://purl.obolibrary.org/obo/HP_0000118
-
-
-
- - is disjoint with
- -
- Protein
- c
-
-
-
-
-
-
-
-
-
-
ProteinClassc
- back to ToC or Class ToC
-
-
-
- IRI: http://purl.obolibrary.org/obo/PR_000000001
-
- - has sub-classes
- -
- d t o 00102000
- c, d t o 01300327
- c, d t o 02300001
- c, d t o 03300101
- c, d t o 05007378
- c, d t o 05007405
- c, d t o 05007527
- c, d t o 05007530
- c, d t o 05007542
- c, d t o 05007557
- c, d t o 05007575
- c, d t o 05007584
- c, d t o 05007599
- c, d t o 05007608
- c, d t o 05007612
- c, d t o 05007613
- c, d t o 05007616
- c, d t o 05007620
- c, d t o 05007621
- c, d t o 05007624
- c, d t o 05007697
- c
-
-
-
-
-
-
-
-
-
-
-
-
Object Properties
-
-
-
-
-
- IRI: http://purl.bioontology.org/ontology/SNOMEDCT/causative_agent_of
-
-
-
-
-
- IRI: http://purl.bioontology.org/ontology/SNOMEDCT/cause_of
-
-
-
-
ChEMBL Drug Indication Associationop
- back to ToC or Object Property ToC
-
-
-
ChEMBL Drug Indication Associationop
- back to ToC or Object Property ToC
-
-
-
- IRI: http://rdf.ebi.ac.uk/terms/chembl#hasDrugIndication
-
- Association between the entity and a ChEMBL Drug Indication
-
-
-
-
-
ChEMBL Mechanism Associationop
- back to ToC or Object Property ToC
-
-
-
ChEMBL Mechanism Associationop
- back to ToC or Object Property ToC
-
-
-
- IRI: http://rdf.ebi.ac.uk/terms/chembl#hasMechanism
-
- Association between the entity and a ChEMBL Mechanism of Action
-
-
-
-
-
ChEMBL Molecule Associationop
- back to ToC or Object Property ToC
-
-
-
ChEMBL Molecule Associationop
- back to ToC or Object Property ToC
-
-
-
- IRI: http://rdf.ebi.ac.uk/terms/chembl#hasMolecule
-
- Association between the entity and a ChEMBL Molecule
-
-
-
-
-
ChEMBL Target Associationop
- back to ToC or Object Property ToC
-
-
-
ChEMBL Target Associationop
- back to ToC or Object Property ToC
-
-
-
- IRI: http://rdf.ebi.ac.uk/terms/chembl#hasTarget
-
- Association between the entity and a ChEMBL Target
-
-
-
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#hasSideEffect
-
-
-
-
Drug For Drug-Phenotype Indicationop
- back to ToC or Object Property ToC
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#drugForDrugIndication
-
-
-
-
Drug For Drug-Phenotype Side Effectop
- back to ToC or Object Property ToC
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#drugForSideEffect
-
-
-
-
-
Drug-Phenotype Side Effect Has Phenotypeop
- back to ToC or Object Property ToC
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#hasPhenotype
-
-
-
-
Drug-Target Association Has Drugop
- back to ToC or Object Property ToC
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#mechanismHasMolecule
-
-
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#hasTarget
-
-
-
-
-
- IRI: http://purl.bioontology.org/ontology/SNOMEDCT/due_to
-
-
-
-
-
- IRI: http://semanticscience.org/resource/SIO_010078
-
- - Is defined by
- -
- http://semanticscience.org/ontology/sio.owl
-
-
-
- - Example
- -
-
an open reading frame encodes a protein (it contains information that specifies the amino acid composition and topology)
-
-
-
-
-
-
-
- IRI: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#R41
-
-
- - has domain
- -
- Gene
- c
-
- - has range
- -
- Organism
- c
-
-
-
-
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Gene_Mutant_Encodes_Gene_Product_Sequence_Variationop
- back to ToC or Object Property ToC
-
-
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- IRI: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#R178
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-
-
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Gene_Product_Has_Organism_Sourceop
- back to ToC or Object Property ToC
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-
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- IRI: http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#R45
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-
-
-
-
-
- IRI: http://purl.bioontology.org/ontology/SNOMEDCT/has_causative_agent
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-
-
-
-
-
-
- IRI: http://semanticscience.org/resource/SIO_000028
-
- - Is defined by
- -
- http://semanticscience.org/ontology/sio.owl
-
-
-
- - Example
- -
-
a collection of cars has as a car as a part;a car has an engine as a part; a car has a piston as a part;
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-
-
-
-
-
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#indicationHasMolecule
-
-
-
-
-
- IRI: http://semanticscience.org/resource/SIO_001403
-
- x is associated with y when x and y are logically or statistically related to one another.
-
-
- - Is defined by
- -
- http://semanticscience.org/ontology/sio.owl
-
-
-
-
-
-
-
-
-
- IRI: http://semanticscience.org/resource/SIO_000061
-
- - Is defined by
- -
- http://semanticscience.org/ontology/sio.owl
-
-
-
- - Example
- -
-
A parasite in the interior of a person's intestine is located in their intestinal lumen.
-
-
-
-
-
-
-
-
-
-
-
- IRI: http://semanticscience.org/resource/SIO_000062
-
- - Is defined by
- -
- http://semanticscience.org/ontology/sio.owl
-
-
-
- - Example
- -
-
a car is a participant in a car race; glucose is a participant in glycolysis
-
-
-
-
-
-
-
-
-
- IRI: http://semanticscience.org/resource/SIO_000292
-
- - Is defined by
- -
- http://semanticscience.org/ontology/sio.owl
-
-
-
- - Example
- -
-
glucose is a target in the hexokinase-mediated conversion of glucose to glucose-6-phosphate.
-
-
-
-
-
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Phenotype For Drug-Phenotype Side Effectop
- back to ToC or Object Property ToC
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#phenotypeForSideEffect
-
-
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Phenotype Side Effect Due To DDIop
- back to ToC or Object Property ToC
-
-
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- IRI: https://w3id.org/eboca/sem-disnet#isSideEffect
-
-
-
-
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#sideEffectHasMolecule
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Data Properties
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-
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- IRI: http://rdf.ebi.ac.uk/terms/chembl#atcClassification
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- ATC Classification Code
-
-
-
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#category
-
-
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#causality
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ChEMBL Mechanism Action Typedp
- back to ToC or Data Property ToC
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-
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ChEMBL Mechanism Action Typedp
- back to ToC or Data Property ToC
-
-
-
- IRI: http://rdf.ebi.ac.uk/terms/chembl#mechanismActionType
-
- Type of action of the drug on the target e.g., agonist/antagonist etc (foreign key to action_type table)
-
-
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-
-
ChEMBL Molecule Development Phasedp
- back to ToC or Data Property ToC
-
-
-
ChEMBL Molecule Development Phasedp
- back to ToC or Data Property ToC
-
-
-
- IRI: http://rdf.ebi.ac.uk/terms/chembl#highestDevelopmentPhase
-
- The highest phase the molecule has reached in drug approval process (4 = approved)
-
-
-
-
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ChEMBL Substance Entity Typedp
- back to ToC or Data Property ToC
-
-
-
ChEMBL Substance Entity Typedp
- back to ToC or Data Property ToC
-
-
-
- IRI: http://rdf.ebi.ac.uk/terms/chembl#substanceType
-
- ChEMBL Substance Entity Type
-
-
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ChEMBL Target Entity Typedp
- back to ToC or Data Property ToC
-
-
-
ChEMBL Target Entity Typedp
- back to ToC or Data Property ToC
-
-
-
- IRI: http://rdf.ebi.ac.uk/terms/chembl#targetType
-
- Describes whether target is a protein, an organism, a tissue etc.
-
-
-
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#chemicalStructure
-
-
-
-
Chromosome No Versiondp
- back to ToC or Data Property ToC
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#chrVersion
-
-
- - has domain
- -
- Gene
- c
-
- - has range
- -
- string
-
-
-
-
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#concentration
-
-
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#confidenceValue
-
-
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#consequence
-
-
-
-
Disease-ncRNA Association typedp
- back to ToC or Data Property ToC
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#type
-
-
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#geneSequence
-
-
- - has domain
- -
- Gene
- c
-
- - has range
- -
- string
-
-
-
-
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#geo
-
-
-
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#inchiKey
-
-
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#rnaCategory
-
-
-
-
Protein sequence for given ChEMBL entitydp
- back to ToC or Data Property ToC
-
-
-
Protein sequence for given ChEMBL entitydp
- back to ToC or Data Property ToC
-
-
-
- IRI: http://rdf.ebi.ac.uk/terms/chembl#proteinSequence
-
- Protein sequence for given ChEMBL entity
-
-
-
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#sample
-
-
-
-
Sequence end positiondp
- back to ToC or Data Property ToC
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#seqEnd
-
-
- - has domain
- -
- Gene
- c
-
- - has range
- -
- integer
-
-
-
-
-
-
Sequence start positiondp
- back to ToC or Data Property ToC
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#seqStart
-
-
- - has domain
- -
- Gene
- c
-
- - has range
- -
- integer
-
-
-
-
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#strand
-
-
- - has domain
- -
- Gene
- c
-
- - has range
- -
- integer
-
-
-
-
-
-
-
- IRI: https://w3id.org/eboca/sem-disnet#synonymous
-
-
-
-
The ChEMBL ID for a given entitydp
- back to ToC or Data Property ToC
-
-
-
The ChEMBL ID for a given entitydp
- back to ToC or Data Property ToC
-
-
-
- IRI: http://rdf.ebi.ac.uk/terms/chembl#chemblId
-
-
-
-
Legend back to ToC
-
-c: Classes
-op: Object Properties
-dp: Data Properties
-
-
-
-
-
-
-
-
References back to ToC
-
-Add your references here. It is recommended to have them as a list.
-
-
-
-
Acknowledgments back to ToC
-
-The authors would like to thank Silvio Peroni for developing LODE, a Live OWL Documentation Environment, which is used for representing the Cross Referencing Section of this document and Daniel Garijo for developing Widoco, the program used to create the template used in this documentation.
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-