Axiom
Term Source: NCI
annotated property: FULL_SYN
annotated source: DesignNote
annotated target: DesignNote

Axiom
database_cross_reference: HPO:probinson
annotated property: definition
annotated source: Phenotypic abnormality
annotated target: A phenotypic abnormality.

Axiom
database_cross_reference: SO:ke
annotated property: definition
annotated source: sequence_variant
annotated target: A sequence_variant is a non exact copy of a sequence_feature or genome exhibiting one or more sequence_alteration.

Axiom
database_cross_reference: http://doc-openbio.readthedocs.org/projects/jannovar/en/master/var_effects.html
has_synonym_type: VAR
annotated property: has_exact_synonym
annotated source: sequence_variant
annotated target: Jannovar:sequence_variant

Axiom
has_synonym_type: VAR
annotated property: has_exact_synonym
annotated source: sequence_variant
annotated target: VAAST:sequence_variant

Axiom
database_cross_reference: http://www.openbioinformatics.org/annovar/annovar_download.html
has_synonym_type: VAR
annotated property: has_related_synonym
annotated source: sequence_variant
annotated target: ANNOVAR:unknown

Axiom
Term Source: NCI
annotated property: FULL_SYN
annotated source: Gene_Mutant_Encodes_Gene_Product_Sequence_Variation
annotated target: Gene_Mutant_Encodes_Gene_Product_Sequence_Variation

Axiom
Term Source: NCI
annotated property: FULL_SYN
annotated source: Gene_Found_In_Organism
annotated target: Gene_Found_In_Organism

Axiom
Term Source: NCI
annotated property: FULL_SYN
annotated source: Gene_Product_Has_Organism_Source
annotated target: Gene_Product_Has_Organism_Source

A CTD association between a chemical and a disease
type: Class
bio2rdf vocabulary:identifier: Chemical-Disease-Association
bio2rdf vocabulary:namespace: ctd_vocabulary
in dataset: ctd resource:bio2rdf.dataset.ctd.R3
label: A CTD association between a chemical and a disease [ctd_vocabulary:Chemical-Disease-Association]
Disnet Label: Drug Disease Associaton

Congenital Abnormality
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T019] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Congenital Abnormality [umls:T019]
subclass of: concept

Acquired Abnormality
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T020] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Acquired Abnormality [umls:T020]
subclass of: concept

Cell Component
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T026] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Cell Component [umls:T026]
subclass of: concept

Body Substance
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T031] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Body Substance [umls:T031]
subclass of: concept

Organism Attribute
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T032] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Organism Attribute [umls:T032]
subclass of: concept

Finding
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T033] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Finding [umls:T033]
subclass of: concept

Laboratory or Test Result
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T034] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Laboratory or Test Result [umls:T034]
subclass of: concept

Injury or Poisoning
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T037] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Injury or Poisoning [umls:T037]
subclass of: concept

Physiologic Function
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T039] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Physiologic Function [umls:T039]
subclass of: concept

Organism Function
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T040] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Organism Function [umls:T040]
subclass of: concept

Mental Process
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T041] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Mental Process [umls:T041]
subclass of: concept

Organ or Tissue Function
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T042] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Organ or Tissue Function [umls:T042]
subclass of: concept

Cell Function
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T043] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Cell Function [umls:T043]
subclass of: concept

Molecular Function
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T044] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Molecular Function [umls:T044]
subclass of: concept

Pathologic Function
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T046] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Pathologic Function [umls:T046]
subclass of: concept

Disease or Syndrome
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T047] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Disease or Syndrome [umls:T047]
subclass of: concept

Mental or Behavioral Dysfunction
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T048] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Mental or Behavioral Dysfunction [umls:T048]
subclass of: concept

Cell or Molecular Dysfunction
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T049] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Cell or Molecular Dysfunction [umls:T049]
subclass of: concept

Experimental Model of Disease
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T050] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Experimental Model of Disease [umls:T050]
subclass of: concept

Social Behavior
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T054] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Social Behavior [umls:T054]
subclass of: concept

Individual Behavior
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T055] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Individual Behavior [umls:T055]
subclass of: concept

Laboratory Procedure
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T059] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Laboratory Procedure [umls:T059]
subclass of: concept

Diagnostic Procedure
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T060] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Diagnostic Procedure [umls:T060]
subclass of: concept

Temporal Concept
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T079] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Temporal Concept [umls:T079]
subclass of: concept

Amino Acid, Peptide, or Protein
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T116] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Amino Acid, Peptide, or Protein [umls:T116]
subclass of: concept

Immunologic Factor
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T129] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Immunologic Factor [umls:T129]
subclass of: concept

Sign or Symptom
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T184] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Sign or Symptom [umls:T184]
subclass of: concept

Classification
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T185] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Classification [umls:T185]
subclass of: concept

Anatomical Abnormality
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T190] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Anatomical Abnormality [umls:T190]
subclass of: concept

Neoplastic Process
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T191] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Neoplastic Process [umls:T191]
subclass of: concept

Clinical Attribute
type: Class
in dataset: umlsSTY
comment: UMLS Semantic Type (STY) [umls:T201] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI.
label: Clinical Attribute [umls:T201]
subclass of: concept

Organism
type: Class
code: C14250
Semantic_Type: Organism
Preferred_Name: Organism
Contributing_Source: BRIDG
Contributing_Source: NICHD
ALT_DEFINITION: A living thing, such as an animal, a plant, a bacterium, or a fungus.
ALT_DEFINITION: Any individual living (or previously living) being. EXAMPLE(S): animal, human being
FULL_SYN: BiologicEntity
FULL_SYN: Organism
FULL_SYN: Organismal
FULL_SYN: Organisms
FULL_SYN: Taxon
FULL_SYN: organism
DEFINITION: A living entity.
Disnet Label: Organism

Gene
type: Class
code: C16612
Semantic_Type: Gene or Genome
Preferred_Name: Gene
Contributing_Source: BRIDG
ALT_DEFINITION: A functional unit of heredity that occupies a specific position (locus) on a particular chromosome, is capable of reproducing itself exactly at each cell division, and directs the formation of a protein or other product. Comment Requested: In interest of re-using existing standards, should the above definition of Gene be replaced by the following from the NLM - The basic physical and functional unit of heredity. It is made up of DNA and act as instructions to make molecules called proteins. [Source: http://ghr.nlm.nih.gov/handbook/basics/gene] EXAMPLE(S): BRCA1 gene OTHER NAME(S): NOTE(S):
ALT_DEFINITION: The functional and physical unit of heredity passed from parent to offspring. Genes are pieces of DNA, and most genes contain the information for making a specific protein.
FULL_SYN: Gene
FULL_SYN: Genes
FULL_SYN: gene
DEFINITION: A functional unit of heredity which occupies a specific position on a particular chromosome and serves as the template for a product that contributes to a phenotype or a biological function.
DesignNote: The gene as a functional unit consists of a discrete segment of a giant DNA molecule containing the purine (adenine and guanine) and pyrimidine (cytosine and thymine) bases in the ordered and correct sequence that encodes a specific functional product (i.e., a protein or RNA molecule).
disjoint with: Score
disjoint with: Disease, Disorder or Finding
Disnet Label: Gene

Protein
type: Class
code: C17021
Semantic_Type: Amino Acid, Peptide, or Protein
Preferred_Name: Protein
Contributing_Source: BRIDG
Contributing_Source: GDC
ALT_DEFINITION: A molecule made up of amino acids that are needed for the body to function properly. Proteins are the basis of body structures such as skin and hair and of substances such as enzymes, cytokines, and antibodies.
ALT_DEFINITION: A representation of an organic macromolecule in public resources (e.g., UniProt or NCBI RefSeq) composed of one or more chains (linear polymers) of alpha-L-amino acids linked by peptide bonds and ranging in size from a few thousand to over 1 million Daltons. Comment Requested: In interest of re-using existing standards, should the above definition of Protein be replaced by the following from the NLM -- : A molecule made up of amino acids that are needed for the body to function properly. Proteins are the basis of body structures such as skin and hair and of substances such as enzymes, cytokines, and antibodies. [Source: http://ghr.nlm.nih.gov/glossary=protein] EXAMPLE(S): A protein record from UniProt Knowledgebase: http://www.uniprot.org/uniprot/P38398 OTHER NAME(S): NOTE(S):
FULL_SYN: Protein
FULL_SYN: Protein (NOS)
FULL_SYN: Proteins
FULL_SYN: protein
DEFINITION: A group of complex organic macromolecules composed of one or more chains (linear polymers) of alpha-L-amino acids linked by peptide bonds and ranging in size from a few thousand to over 1 million Daltons. Proteins are fundamental genetically encoded components of living cells with specific structures and functions dictated by amino acid sequence.
disjoint with: Phenotypic abnormality
Disnet Label: Protein

Disease Marker
type: Class
code: C18329
Semantic_Type: Indicator, Reagent, or Diagnostic Aid
Preferred_Name: Disease Marker
FULL_SYN: Disease Marker
FULL_SYN: Marker, Disease
FULL_SYN: Markers, Disease
DEFINITION: Specific molecular signature of disease, physiological measurement, genotype structural or functional characteristic, metabolic changes, or other determinant that may simplify the diagnostic process, make diagnoses more accurate, distinguish different causes of disease, or enable physicians to make diagnoses before symptoms appear and to track disease progression.
Disnet Label: Disease Marker

Protein-Protein Interaction
type: Class
code: C18469
Semantic_Type: Molecular Function
Preferred_Name: Protein-Protein Interaction
FULL_SYN: Protein-Protein Interaction
DEFINITION: Temporary, non-covalent binding between protein molecules. Protein-protein interactions occur as a result of intermolecular physical forces and spatial complementation between domains or motifs. This interaction can be either homotypic or heterotypic and effect protein structure, conformation, and function.
Disnet Label: PPI

Score
type: Class
code: C25338
Semantic_Type: Quantitative Concept
Preferred_Name: Score
Contributing_Source: CDISC
ALT_DEFINITION: A number or range of numeric values that assess and order a result or response for purposes of comparison.
FULL_SYN: SCORE
FULL_SYN: Score
DEFINITION: A number or range of numeric values measuring performance, function, quality, or ability.
disjoint with: Disease, Disorder or Finding
disjoint with: sequence_variant
Disnet Label: Score

Untranslated RNA
type: Class
code: C26549
Semantic_Type: Nucleic Acid, Nucleoside, or Nucleotide
Preferred_Name: Untranslated RNA
FULL_SYN: Functional RNA
FULL_SYN: Non-Coding RNA
FULL_SYN: Noncoding RNA
FULL_SYN: Untranslated RNA
FULL_SYN: ncRNA
DEFINITION: The product of so-called RNA genes; a functional RNA represents the final product of a gene rather than a transient molecule that will be translated into protein.
disjoint with: Disease, Disorder or Finding
Disnet Label: ncRNA

Gene Symbol
type: Class
code: C43568
Semantic_Type: Intellectual Product
Preferred_Name: Gene Symbol
Contributing_Source: BRIDG
Contributing_Source: CTDC
ALT_DEFINITION: A conventional sign used for representing the gene, based on the identified source. EXAMPLE(S): As a string with an optional code, an example of Gene.symbol is as follows: the value "BRCA1" is both the string and the code and the code system name is "HGNC". OTHER NAME(S): NOTE(S):
FULL_SYN: Gene Name
FULL_SYN: Gene Symbol
FULL_SYN: Gene.symbol
FULL_SYN: Official Gene Name
FULL_SYN: gene
DEFINITION: A unique gene name approved by an organism specific nomenclature committee.
Disnet Label: Gene Symbol

Disease, Disorder or Finding
type: Class
code: C7057
Semantic_Type: Conceptual Entity
Preferred_Name: Disease, Disorder or Finding
FULL_SYN: Disease, Disorder or Finding
DEFINITION: A condition that is relevant to human neoplasms and non-neoplastic disorders. This includes observations, test results, history and other concepts relevant to the characterization of human pathologic conditions.
disjoint with: sequence_variant
disjoint with: ChEMBL Substance Class
Disnet Label: Disease

code
type: AnnotationProperty
code: NHC0
Semantic_Type: Conceptual Entity
Preferred_Name: code
FULL_SYN: code
DEFINITION: A property representing a concept unique identifier within the NCI Enterprise Vocabulary Service's NCI Thesaurus.
read only: true
range: string
Disnet Label: Code

Semantic_Type
type: AnnotationProperty
code: P106
Semantic_Type: Conceptual Entity
Display_Name: Semantic Type
Preferred_Name: Semantic_Type
FULL_SYN: Semantic_Type
DEFINITION: A property that represents a description of the sort of thing or category to which a concept belongs in the context of the UMLS semantic network.
DesignNote: In general, applying semantic types aids in allowing users (or computer programs) to draw conclusions about concepts by virtue of the categories to which they have been assigned. We use a set of semantic types developed for the UMLS Metathesaurus. There are currently 134 semantic types in the UMLS.
Disnet Label: Semantic Type

Display_Name
type: AnnotationProperty
code: P107
Semantic_Type: Conceptual Entity
Display_Name: Display Name
Preferred_Name: Display_Name
FULL_SYN: Display Name
FULL_SYN: Display_Name
DEFINITION: A property representing an alternative Preferred Name for use in some NCI systems.
range: string
Disnet Label: Display Name

Preferred_Name
type: AnnotationProperty
code: P108
Semantic_Type: Conceptual Entity
Display_Name: Preferred Name
Preferred_Name: Preferred_Name
FULL_SYN: Preferred Name
FULL_SYN: Preferred Term
FULL_SYN: Preferred_Name
DEFINITION: A property representing the word or phrase that NCI uses by preference to refer to the concept.
range: string
Disnet Label: Preferred Name

Contributing_Source
type: AnnotationProperty
code: P322
Semantic_Type: Conceptual Entity
Display_Name: Contributing Source
Preferred_Name: Contributing_Source
FULL_SYN: Contributing_Source
DEFINITION: A property is used to indicate when a non-EVS entity has contributed to, and has a stake in, a concept. This is used where such entities, within or outside NCI, have indicated the need to be able to track their own concepts. A single concept can have multiple instances of this property if multiple entities have such a defined stake.
Disnet Label: Contributing Source

ALT_DEFINITION
type: AnnotationProperty
code: P325
Semantic_Type: Conceptual Entity
Display_Name: [source] Definition
Preferred_Name: ALT_DEFINITION
FULL_SYN: ALT_DEFINITION
DEFINITION: A property representing the English language definition of a concept from a source other than NCI.
Disnet Label: Alternative Definition

Term Source
type: AnnotationProperty
code: P384
Semantic_Type: Conceptual Entity
Preferred_Name: term-source
DEFINITION: A property representing the organization that is the supplier or owner of each FULL_SYN term.
required: true
Disnet Label: Term Source

FULL_SYN
type: AnnotationProperty
code: P90
Semantic_Type: Conceptual Entity
Display_Name: Term & Source Data
Preferred_Name: FULL_SYN
FULL_SYN: FULL_SYN
FULL_SYN: Synonym with Source Data
DEFINITION: A property representing a fully qualified synonym, contains the string, term type, source, and an optional source code if appropriate. Each subfield is deliniated to facilitate interpretation by software.
Disnet Label: Full Synonym

DEFINITION
type: AnnotationProperty
code: P97
Semantic_Type: Conceptual Entity
Display_Name: Definition
Preferred_Name: DEFINITION
FULL_SYN: DEFINITION
DEFINITION: A property representing the English language definitions of what NCI means by the concept. They may also include information about the definition's source and attribution in a form that can easily be interpreted by software.
Disnet Label: Definition

DesignNote
type: AnnotationProperty
code: P98
Semantic_Type: Conceptual Entity
Display_Name: DesignNote
Preferred_Name: DesignNote
FULL_SYN: DesignNote
DEFINITION: A property representing notations made by NCI vocabulary curators. They are intended to provide supplemental, unstructured information to the user or additional insight about the concept.
range: string
Disnet Label: Design Note

Gene_Mutant_Encodes_Gene_Product_Sequence_Variation
type: ObjectProperty
code: R178
Semantic_Type: Conceptual Entity
Preferred_Name: Gene_Mutant_Encodes_Gene_Product_Sequence_Variation
FULL_SYN: Gene_Mutant_Encodes_Gene_Product_Sequence_Variation
DEFINITION: A role used to indicate that a specific molecular variation or mutation in a gene encodes a gene product sequence variant. The domain and range for this role are 'Gene Mutant' and 'Gene Product Sequence Variation', respectively.
domain: Gene
range: sequence_variant
inverse of: is associated with
Disnet Label: Gene Associated With Variant

Gene_Found_In_Organism
type: ObjectProperty
code: R41
Semantic_Type: Conceptual Entity
Display_Name: Found In Organism
Preferred_Name: Gene_Found_In_Organism
FULL_SYN: Gene_Found_In_Organism
DEFINITION: A role used to specify the organism of origin for a gene. It may be used to differentiate genes with the same name and functions that originate from different organisms. The domain and range for this role are 'Gene' and 'Organism', respectively.
DesignNote: Currently, we only model human genes, but this role has obvious utility in future, if other organisms are modeled as well.
domain: Gene
range: Organism
Disnet Label: Gene In Organism

Gene_Product_Has_Organism_Source
type: ObjectProperty
code: R45
Semantic_Type: Conceptual Entity
Display_Name: Has Organism Source
Preferred_Name: Gene_Product_Has_Organism_Source
FULL_SYN: Gene_Product_Has_Organism_Source
DEFINITION: A role used to differentiate homologous proteins from different organisms. The domain and range for this role are 'Gene Product' and 'Organism', respectively.
domain: Protein
range: Organism
Disnet Label: Protein In Organism

default
type: AnnotationProperty
range: string
Disnet Label: Default

xRef Source
type: AnnotationProperty
DEFINITION: A property representing the name of the organization to which an NCI Thesaurus concept is being linked to by cross reference.
Disnet Label: XRef Source

Adverse reaction to drug
type: Class
Preferred_Name: Adverse reaction to drug
definition: All noxious and unintended responses to a medicinal product related to any dose should be considered adverse drug reactions (from US FDA 'Guideline for Industry, Clinical Safety Data Management: Definitions and Standards for Expedited Reporting'). All noxious and unintended responses to a medicinal product related to any dose should be considered adverse drug reactions (from US FDA Guideline for Industry, Clinical Safety Data Management: Definitions and Standards for Expedited Reporting).
alternative label: Drug reaction Adverse reaction caused by drug (disorder) ADR - Adverse drug reaction Adverse reaction to medication Adverse reaction caused by drug Adverse drug effect Adverse drug reaction
Disnet Label: Drug Phenotype Side Effect

Causative agent of
type: ObjectProperty
inverse of: Has causative agent
Disnet Label: Causative agent of

Cause of
type: ObjectProperty
inverse of: Due to
Disnet Label: Cause Of

Due to
type: ObjectProperty
Disnet Label: Due To

Has causative agent
type: ObjectProperty
Disnet Label: Has causative agent

Phenotypic abnormality
type: Class
tree view: HP_0000001
definition: A phenotypic abnormality.
database_cross_reference: UMLS:C4021819
has_exact_synonym: Organ abnormality
has_obo_namespace: human_phenotype
id: HP:0000118
comment: This is the root of the phenotypic abnormality subontology of the HPO.
notation: HP:0000118
Disnet Label: Disease class

definition
type: AnnotationProperty
Disnet Label: OBO Definition

ProteinClass
type: Class
Disnet Label: Protein class

sequence_variant
type: Class
definition: A sequence_variant is a non exact copy of a sequence_feature or genome exhibiting one or more sequence_alteration.
has_exact_synonym: Jannovar:sequence_variant
has_exact_synonym: VAAST:sequence_variant
has_exact_synonym: sequence variant
has_obo_namespace: sequence
has_related_synonym: ANNOVAR:unknown
id: SO:0001060
Disnet Label: Variant

ChEMBL Drug Indication Class
type: Class
Disnet Label: Drug Phenotype Indication

ChEMBL Mechanism Class
type: Class
Disnet Label: Drug Target Association

ChEMBL Substance Class
type: Class
disjoint with: ChEMBL Target Class
disjoint with: Phenotype
Disnet Label: Drug

ChEMBL Target Class
type: Class
Disnet Label: Target

ATC Code
type: DatatypeProperty
description: ATC Classification Code
domain: ChEMBL Substance Class
range: string
Disnet Label: ATC Code

The ChEMBL ID for a given entity
type: DatatypeProperty
domain: Class
  union of: Drug-Phenotype Indication
  union of: Drug-Phenotype Side Effect
range: string
Disnet Label: CHEMBL ID

ChEMBL Drug Indication Association
type: ObjectProperty
description: Association between the entity and a ChEMBL Drug Indication
Disnet Label: ChEMBL Has Drug Indication

ChEMBL Mechanism Association
type: ObjectProperty
description: Association between the entity and a ChEMBL Mechanism of Action
inverse of: ChEMBL Molecule Association
Disnet Label: ChEMBL Has Drug Target

ChEMBL Molecule Association
type: ObjectProperty
description: Association between the entity and a ChEMBL Molecule
Disnet Label: ChEMBL Has Drug

ChEMBL Target Association
type: ObjectProperty
description: Association between the entity and a ChEMBL Target
inverse of: Association between ChEMBL Target and Mechanism
Disnet Label: ChEMBL Has Target

ChEMBL Molecule Development Phase
type: DatatypeProperty
description: The highest phase the molecule has reached in drug approval process (4 = approved)
domain: Class
  union of: Drug-Phenotype Indication
  union of: Drug-Phenotype Side Effect
range: integer
Disnet Label: Highest Development Phase

Association between ChEMBL Target and Mechanism
type: ObjectProperty
Disnet Label: Is Target

ChEMBL Mechanism Action Type
type: DatatypeProperty
description: Type of action of the drug on the target e.g., agonist/antagonist etc (foreign key to action_type table)
domain: Drug-Target Association
range: string
Disnet Label: Drug Target Action Type

Protein sequence for given ChEMBL entity
type: DatatypeProperty
description: Protein sequence for given ChEMBL entity
domain: Protein
range: string
Disnet Label: Protein Sequence

ChEMBL Substance Entity Type
type: DatatypeProperty
description: ChEMBL Substance Entity Type
domain: ChEMBL Substance Class
range: string

ChEMBL Target Entity Type
type: DatatypeProperty
description: Describes whether target is a protein, an organism, a tissue etc.
domain: ChEMBL Target Class
range: string

has attribute
type: ObjectProperty
description: has attribute is a relation that associates a entity with an attribute where an attribute is an intrinsic characteristic such as a quality, capability, disposition, function, or is an externally derived attribute determined from some descriptor (e.g. a quantity, position, label/identifier) either directly or indirectly through generalization of entities of the same type.
subset: core
domain: Class
  union of: Disease, Disorder or Finding
  union of: Phenotype
range: Class
  union of: Disease Marker
  union of: concept
inverse of: is attribute of
Disnet Label: Has Attribute

is attribute of
type: ObjectProperty
description: is attribute of is a relation that associates an attribute with an entity where an attribute is an intrinsic characteristic such as a quality, capability, disposition, function, or is an externally derived attribute determined from some descriptor (e.g. a quantity, position, label/identifier) either directly or indirectly through generalization of entities of the same type.
domain: Class
  union of: Disease Marker
  union of: concept
range: Class
  union of: Disease, Disorder or Finding
  union of: Phenotype
Disnet Label: Is Attribute Of

has part
type: ObjectProperty
description: has part is a transitive, reflexive and antisymmetric relation between a whole and itself or a whole and its part.
domain: Class
  union of: Pathway
  union of: group of disorders
range: Class
  union of: Gene
  union of: Disease, Disorder or Finding
sub property of: is location of
inverse of: is part of
example: a collection of cars has as a car as a part;a car has an engine as a part; a car has a piston as a part;
Disnet Label: Has Part

has member
type: ObjectProperty
type: IrreflexiveProperty
description: has member is a mereological relation between a collection and an item.
subset: core
domain: Class
  union of: Phenotypic abnormality
  union of: ProteinClass
range: Class
  union of: Protein
  union of: Disease, Disorder or Finding
sub property of: has attribute
inverse of: is member of
example: a collection of cars has as a car as a member
Disnet Label: Has Member

is located in
type: ObjectProperty
description: A is located in B iff the spatialtemporial region occupied by A is part of the spatialtemporal region occupied by B. [T][R]
equivalent to: OBO_REL:located_in
subset: core
domain: sequence_variant
range: Class
  union of: sequence start position
  union of: chromosome
inverse of: is location of
example: A parasite in the interior of a person's intestine is located in their intestinal lumen.
Disnet Label: Is Located In

is participant in
type: ObjectProperty
description: is participant in is a relation that describes the participation of the subject in the (processual) object.
domain: Class
  union of: Protein
  union of: ChEMBL Substance Class
range: Class
  union of: Protein-Protein Interaction
  union of: drug drug interaction
inverse of: has participant
example: a car is a participant in a car race; glucose is a participant in glycolysis
Disnet Label: Is Participant In

is part of
type: ObjectProperty
description: is part of is a transitive, reflexive and anti-symmetric mereological relation between a whole and itself or a part and its whole.
equivalent to: OBO_REL:part_of
subset: core
domain: Class
  union of: Gene
  union of: Disease, Disorder or Finding
range: Class
  union of: Pathway
  union of: group of disorders
sub property of: is located in
Disnet Label: Is Part Of

is member of
type: ObjectProperty
description: is member of is a mereological relation between a item and a collection.
domain: Class
  union of: Protein
  union of: Disease, Disorder or Finding
range: Class
  union of: Phenotypic abnormality
  union of: ProteinClass
sub property of: is attribute of
Disnet Label: Is Member Of

has participant
type: ObjectProperty
description: has participant is a relation that describes the participation of the object in the (processual) subject.
equivalent to: OBO_REL:has_participant
subset: core
domain: Class
  union of: Protein-Protein Interaction
  union of: drug drug interaction
range: Class
  union of: Protein
  union of: ChEMBL Substance Class
Disnet Label: Has Participant

is location of
type: ObjectProperty
description: A is location of B iff the spatialtemporal region occupied by A has the spatialtemporal region occupied by B as a part. [T][R]
subset: nlp+
domain: Class
  union of: sequence start position
  union of: chromosome
range: sequence_variant
Disnet Label: Is Location Of

is represented by
type: ObjectProperty
description: is represented by: a relation between an entity and some symbol.
domain: Gene
range: Gene Symbol
sub property of: is referred to by
inverse of: represents
Disnet Label: Is Represented By

represents
type: ObjectProperty
description: a represents b when a serves as a sign, symbol or model of b.
subset: core
domain: Gene Symbol
range: Gene
sub property of: refers to
Disnet Label: Represents

is referred to by
type: ObjectProperty
description: A is referred to by B iff B is an informational entity that makes reference to A.
domain: Class
  union of: Gene
  union of: Untranslated RNA
  union of: Disease, Disorder or Finding
  union of: sequence_variant
  union of: ChEMBL Substance Class
  union of: annual incidence
  union of: group of disorders
  union of: Phenotype
range: Class
  union of: association
  union of: gene-disease association
  union of: Disease-ncRNA Association
  union of: Disease-Phenotype Association
  union of: Drug-Disease Association
  union of: Prevalence
inverse of: refers to
Disnet Label: Is Referred To By

is measurement value of
type: ObjectProperty
description: is measurement value of is a relation between a value and the entity that it is a measurement of.
domain: Class
  union of: Score
  union of: DisGeNET disease specificity
  union of: DisGeNET Pleiotropy Index
range: Class
  union of: Disease, Disorder or Finding
  union of: sequence_variant
  union of: association
  union of: gene-disease association
sub property of: is attribute of
inverse of: has measurement value
Disnet Label: Is Measurement Value Of

has measurement value
type: ObjectProperty
description: has measurement value is a relation between a quality/realizable and a measurement value.
subset: core
domain: Class
  union of: Disease, Disorder or Finding
  union of: sequence_variant
  union of: association
  union of: gene-disease association
range: Class
  union of: Score
  union of: DisGeNET disease specificity
  union of: DisGeNET Pleiotropy Index
sub property of: has attribute
Disnet Label: Has Measurement Value

has target
type: ObjectProperty
description: has target is a relation between a process and an entity, where the entity is present at the beginning of the process and undergoes a change or transformation in the process.
domain: Class
  union of: Organism
  union of: Protein
range: ChEMBL Target Class
inverse of: is target in
Disnet Label: Has Target

is target in
type: ObjectProperty
description: is target in is a relation between an entity and a process, where the entity is present at the beginning of the process and undergoes a change or transformation in the process.
domain: ChEMBL Target Class
range: Class
  union of: Organism
  union of: Protein
example: glucose is a target in the hexokinase-mediated conversion of glucose to glucose-6-phosphate.
Disnet Label: Is Target In

has value
type: DatatypeProperty
type: FunctionalProperty
description: A relation between a informational entity and its actual value (numeric, date, text, etc).
subset: sadi
subset: core
subset: nlp
subset: relations
domain: Class
  union of: Score
  union of: Gene Symbol
  union of: sequence start position
  union of: chromosome
  union of: DisGeNET disease specificity
  union of: DisGeNET Pleiotropy Index
  union of: annual incidence
  union of: Drug-Disease Association
range: Datatype
  union of: double
  union of: integer
  union of: string
Disnet Label: Has Value

concept
type: Class
description: A concept is term that refers to a generalization of a set of attributes or entities.
Disnet Label: Semantic Type

refers to
type: ObjectProperty
description: refers to is a relation between one entity and the entity that it makes reference to.
subset: core
subset: nlp+
domain: Class
  union of: association
  union of: gene-disease association
  union of: Disease-ncRNA Association
  union of: Disease-Phenotype Association
  union of: Drug-Disease Association
  union of: Prevalence
range: Class
  union of: Gene
  union of: Untranslated RNA
  union of: Disease, Disorder or Finding
  union of: sequence_variant
  union of: ChEMBL Substance Class
  union of: annual incidence
  union of: group of disorders
  union of: Phenotype
Disnet Label: Refers To

sequence start position
type: Class
description: A sequence start position is the start position for a sequence of characters.
Disnet Label: Chromosome position

association
type: Class
description: An assocation is a relationship between two or more entities derived by some informational analysis.
disjoint with: gene-disease association
disjoint with: Disease-ncRNA Association
disjoint with: Drug-Disease Association
Disnet Label: Association

chromosome
type: Class
description: A chromosome is a molecular complex of circular or linear DNA and bound proteins.
Disnet Label: Chromosome

gene-disease association
type: Class
description: A gene-disease association is an association between a gene and a disease.
subclass of: association
disjoint with: Disease-ncRNA Association
disjoint with: Drug-Disease Association
Disnet Label: Gene Disease Association

drug drug interaction
type: Class
description: A drug-drug interaction is an interaction in which two drugs interact in such a way to produce a non-additive biological response.
subclass of: association
disjoint with: Drug-Disease Association
disjoint with: Drug-Phenotype Indication
disjoint with: Drug-Phenotype Side Effect
disjoint with: Drug-Target Association
Disnet Label: DDI

DisGeNET disease specificity
type: Class
description: DisGeNET Disease specificity is a measure of disease coverage. It is calculated from the negative base 2 log of the ratio of number of diseases associated to the total number of diseases. The measure is described here: http://www.disgenet.org/web/DisGeNET/menu/dbinfo#specificity
Disnet Label: Disease Specificity

DisGeNET Pleiotropy Index
type: Class
description: The DisGeNET pleiotropy index is a measure of specificity as it pertains to classes of disease. The disease pleotropy index is computed from the ratio of the number of disease classes associated with an entity over the total number of disease classes multplied by 100. The measure is defined here: http://www.disgenet.org/web/DisGeNET/menu/dbinfo#pleiotropy
Disnet Label: Disease Pleiotropy

is associated with
type: ObjectProperty
description: x is associated with y when x and y are logically or statistically related to one another.
domain: sequence_variant
range: Gene
Disnet Label: Is Associated With

encodes
type: ObjectProperty
description: A relation between two objects, in which the first object contains information that is used to produce the second object.
domain: Gene
range: Protein
inverse of: is encoded by
example: an open reading frame encodes a protein (it contains information that specifies the amino acid composition and topology)
Disnet Label: Encodes

is encoded by
type: ObjectProperty
description: A relation between two objects, in which the first object is produced from the information contained in the second object.
domain: Protein
range: Gene
Disnet Label: Is Encoded By

equivalentTo
type: AnnotationProperty
Disnet Label: Equivalent To

Pathway
type: Class
comment: A biological process representing a set of interactions and relationships among genes, proteins, metabolites, and other factors in the context of cellular compartments, tissues and organisms.
in scheme: wp#
Disnet Label: Pathway

DTO_00102000
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_00102000] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_01300327
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_01300327] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_02300001
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_02300001] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_03300101
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_03300101] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_05007378
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_05007378] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_05007405
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_05007405] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_05007527
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_05007527] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_05007530
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_05007530] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_05007542
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_05007542] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_05007557
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_05007557] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_05007575
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_05007575] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_05007584
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_05007584] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_05007599
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_05007599] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_05007608
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_05007608] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_05007612
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_05007612] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_05007613
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_05007613] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_05007616
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_05007616] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_05007620
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_05007620] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_05007621
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_05007621] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_05007624
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_05007624] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

DTO_05007697
type: Class
in dataset: ProteinClass
comment: DTO protein class [dto:DTO_05007697] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id.
subclass of: ProteinClass

database_cross_reference
type: AnnotationProperty
DEFINITION: A property representing a reference to an identical or very similar object in another database.
label: xRef
Disnet Label: Database Cross Reference

has_exact_synonym
type: AnnotationProperty
Disnet Label: Has Exact Synonym

has_obo_namespace
type: AnnotationProperty
Disnet Label: Has OBO Namespace

has_related_synonym
type: AnnotationProperty
Disnet Label: Has Related Synonym

has_synonym_type
type: AnnotationProperty
Disnet Label: Has Synonym Type

id
type: AnnotationProperty
Disnet Label: OBO ID

annual incidence
type: Class
definition: Number of newly diagnosed cases in a population in 1 year.
Disnet Label: Prevalence class

group of disorders
type: Class
definition: A collection of clinical entities sharing a set of common features.
Disnet Label: Orpha

geography
type: Class
definition: Refers to a country, a continent or the whole world.
Disnet Label: Prevalence

preferred label
type: AnnotationProperty
comment: A resource has no more than one value of skos:prefLabel per language tag, and no more than one value of skos:prefLabel without language tag.
comment: The range of skos:prefLabel is the class of RDF plain literals.
comment: skos:prefLabel, skos:altLabel and skos:hiddenLabel are pairwise disjoint properties.
sub property of: label
definition: The preferred lexical label for a resource, in a given language.

SEM-DISNET
type: Ontology
contributor: Andrea Álvarez Pérez (MEDAL) Ana Iglesias Molina (OEG) Lucía Prieto Santamaría (MEDAL) Alejandro Rodríguez González (MEDAL)
created: 2022-03-30
creator: MEDAL: https://medal.ctb.upm.es/ OEG: https://oeg.fi.upm.es/
description: SEM-DISNET ontology provides a integrated ontology used to describe the define entities, which appear in the DISNET database. It is an ontology aimed at facilitating the analysis of biomedical data, allowing the discovery of new patterns and associations between genes, drugs and their targets to be applied in cases of drug repositioning. This project has been carried out within the DISNET project of MEDAL Laboratory (Medical Data Analytics) at the CTB-UPM, together with DRUGS4COVID, developed by the OEG-UPM (Ontology Engineering Group). DISNET website: https://disnet.ctb.upm.es/ OEG website: https://oeg.fi.upm.es/
license: cc-by-nc-sa4.0
preferred namespace prefix: disnet
preferred namespace uri: http://w3id.org/eboca/sem-disnet

Disease-ncRNA Association
type: Class
comment: A disease-ncRNA association is an association between a disease and an untranslated RNA (ncRNA).
subclass of: association
disjoint with: Drug-Disease Association
Disnet Label: Disease ncRNA Association

Disease-Phenotype Association
type: Class
comment: A disease-phenotype association is an association between disease and a phenotype, which corresponds to a subjective evidence of disease perceived by the patient.
subclass of: association
Disnet Label: Disease Phenotype Association

Disease-Variant Association
type: Class
comment: Association between a disease and a genetic variant.
subclass of: association
Disnet Label: Disease Variant Association

Drug-Disease Association
type: Class
description: Drug-disease associations refer to the effects that can be induced by the interaction between a drug and a disease.
subclass of: A CTD association between a chemical and a disease
subclass of: association
disjoint with: Drug-Phenotype Indication
disjoint with: Drug-Phenotype Side Effect
disjoint with: Drug-Target Association
Disnet Label: Drug Disease Association

Drug Disease Inferred
type: Class
comment: Drug Disease Associations not classifed as Therapeutic or Marker which are given an associated inferred score.
subclass of: Drug-Disease Association
Disnet Label: Drug Disease Inferred

Drug Disease Marker
type: Class
comment: Drug that acts like a marker when associated with a disease. A chemical that correlates with a disease or may play a role in the etiology of a disease.
subclass of: Drug-Disease Association
Disnet Label: Drug Disease Marker

Drug Disease Therapeutic
type: Class
comment: Drug that has a therapeutic effect when associated with a disease. The drug is used to treat the disease in order to reduce or eliminate its symptoms.
subclass of: Drug-Disease Association
Disnet Label: Drug Disease Therapeutic

Drug-Phenotype Indication
type: Class
comment: Relationship between the desirable measurable effects that cause changes in a patient's phenotype and the response to treatment with a drug which is indicated to treat them.
subclass of: ChEMBL Drug Indication Class
subclass of: association
disjoint with: Drug-Phenotype Side Effect
disjoint with: Drug-Target Association
Disnet Label: Drug Phenotype Indication

Drug-Phenotype Side Effect
type: Class
comment: Secondary and undesirable measurable effects that cause patient phenotype changes in response to the treatment with a drug.
subclass of: Adverse reaction to drug
subclass of: association
disjoint with: Drug-Target Association
Disnet Label: Drug Phenotype Side Effect

Drug-Target Association
type: Class
comment: Association between a drug and a target in order to achieve disease treatment by different action types or mechanism of action.
subclass of: ChEMBL Mechanism Class
subclass of: association
Disnet Label: Drug Target Association

Phenotype
type: Class
comment: Observable and detectable signs in a patient due to the effects caused by a disease or a drug causing changes in their original appearence.
Disnet Label: Phenotype

Protein-Protein Interaction
type: Class
comment: Association between two proteins by physical contacts of high specificity that occur in a specific molecular context with a certain confidence value.
subclass of: Protein-Protein Interaction
subclass of: association
Disnet Label: PPI

Prevalence
type: Class
comment: Association between an oprhan disease and the incidence according to the geographical location.
subclass of: association
subclass of: geography
Disnet Label: Prevalence

Category
type: DatatypeProperty
domain: Disease-ncRNA Association
range: string
Disnet Label: Category

Causality
type: DatatypeProperty
domain: Disease-ncRNA Association
range: string
Disnet Label: Causality

Chemical Structure
type: DatatypeProperty
domain: ChEMBL Substance Class
range: string
Disnet Label: Chemical Structure

Chromosome No Version
type: DatatypeProperty
domain: Gene
range: string
Disnet Label: Chromosome Version

Concentration
type: DatatypeProperty
domain: Disease Marker
range: string
Disnet Label: Marker Concentration

Confidence Value
type: DatatypeProperty
domain: Protein-Protein Interaction
range: string
Disnet Label: PPI Confidence Value

Consequence
type: DatatypeProperty
domain: sequence_variant
range: string
Disnet Label: Variant Consequence

Disnet Label
type: AnnotationProperty
Disnet Label: Disnet Label

Drug For Drug-Phenotype Indication
type: ObjectProperty
domain: ChEMBL Substance Class
range: Drug-Phenotype Indication
sub property of: ChEMBL Drug Indication Association
sub property of: is referred to by
inverse of: Indication Has Drug
Disnet Label: Drug For Drug Phenotype Indication

Drug For Drug-Target Association
type: ObjectProperty
domain: ChEMBL Substance Class
range: Drug-Target Association
sub property of: ChEMBL Mechanism Association
sub property of: is referred to by
inverse of: Drug-Target Association Has Drug
Disnet Label: Drug For Drug Target Association

Drug For Drug-Phenotype Side Effect
type: ObjectProperty
domain: ChEMBL Substance Class
range: Drug-Phenotype Side Effect
sub property of: Causative agent of
sub property of: is referred to by
inverse of: Side Effect Has Drug
Disnet Label: Drug For Drug-Phenotype Side Effect

Gene Sequence
type: DatatypeProperty
domain: Gene
range: string
Disnet Label: Gene Sequence

Geography
type: DatatypeProperty
domain: Prevalence
range: string
Disnet Label: Geography

Drug-Phenotype Side Effect Has Phenotype
type: ObjectProperty
domain: Drug-Phenotype Side Effect
range: Phenotype
sub property of: Due to
sub property of: refers to
inverse of: Phenotype For Drug-Phenotype Side Effect
Disnet Label: Drug-Phenotype Side Effect Has Phenotype

DDI Has Side Effect
type: ObjectProperty
domain: drug drug interaction
range: Phenotype
inverse of: Phenotype Side Effect Due To DDI
Disnet Label: DDI Has Side Effect

Drug-Target Has Target
type: ObjectProperty
domain: Drug-Target Association
range: ChEMBL Target Class
sub property of: ChEMBL Target Association
sub property of: refers to
inverse of: Target For Drug-Target Association
Disnet Label: Drug-Target Has Target

Inchi Key
type: DatatypeProperty
domain: ChEMBL Substance Class
range: string
Disnet Label: Inchi Key

Indication Has Drug
type: ObjectProperty
domain: Drug-Phenotype Indication
range: ChEMBL Substance Class
sub property of: ChEMBL Molecule Association
sub property of: refers to
Disnet Label: Indication Has Drug

Phenotype Side Effect Due To DDI
type: ObjectProperty
domain: Phenotype
range: drug drug interaction
Disnet Label: Phenotype Side Effect Due To DDI

Drug-Target Association Has Drug
type: ObjectProperty
domain: Drug-Target Association
range: ChEMBL Substance Class
sub property of: ChEMBL Molecule Association
sub property of: refers to
Disnet Label: Drug-Target Association Has Drug

Phenotype For Drug-Phenotype Side Effect
type: ObjectProperty
domain: Phenotype
range: Drug-Phenotype Side Effect
sub property of: Cause of
sub property of: is referred to by
Disnet Label: Phenotype For Drug-Phenotype Side Effect

ncRNA Category
type: DatatypeProperty
domain: Untranslated RNA
range: string
Disnet Label: ncRNA Category

Sample
type: DatatypeProperty
domain: Disease Marker
range: string
Disnet Label: Marker Sample

Sequence end position
type: DatatypeProperty
domain: Gene
range: integer
Disnet Label: Sequence End Position

Sequence start position
type: DatatypeProperty
domain: Gene
range: integer
Disnet Label: Sequence Start Position

Side Effect Has Drug
type: ObjectProperty
domain: Drug-Phenotype Side Effect
range: ChEMBL Substance Class
sub property of: Has causative agent
sub property of: refers to
Disnet Label: Side Effect Has Drug

Strand
type: DatatypeProperty
domain: Gene
range: integer
Disnet Label: Strand

Synonymous
type: DatatypeProperty
domain: ChEMBL Substance Class
range: string

Target For Drug-Target Association
type: ObjectProperty
domain: ChEMBL Target Class
range: Drug-Target Association
sub property of: Association between ChEMBL Target and Mechanism
sub property of: is referred to by
Disnet Label: Is Target For Drug Target Association

Disease-ncRNA Association type
type: DatatypeProperty
domain: Disease-ncRNA Association
range: string