@prefix : . @prefix owl: . @prefix rdf: . @prefix xml: . @prefix xsd: . @prefix rdfs: . @base . rdf:type owl:Ontology ; """Andrea Álvarez Pérez (MEDAL) Ana Iglesias Molina (OEG) Lucía Prieto Santamaría (MEDAL) Alejandro Rodríguez González (MEDAL)""" ; "2022-03-30" ; """MEDAL: https://medal.ctb.upm.es/ OEG: https://oeg.fi.upm.es/""" ; """SEM-DISNET ontology provides a integrated ontology used to describe the define entities, which appear in the DISNET database. It is an ontology aimed at facilitating the analysis of biomedical data, allowing the discovery of new patterns and associations between genes, drugs and their targets to be applied in cases of drug repositioning. This project has been carried out within the DISNET project of MEDAL Laboratory (Medical Data Analytics) at the CTB-UPM, together with DRUGS4COVID, developed by the OEG-UPM (Ontology Engineering Group). DISNET website: https://disnet.ctb.upm.es/ OEG website: https://oeg.fi.upm.es/""" ; ; "SEM-DISNET" ; "disnet" ; . ################################################################# # Annotation properties ################################################################# ### http://bio2rdf.org/bio2rdf_vocabulary:identifier rdf:type owl:AnnotationProperty . ### http://bio2rdf.org/bio2rdf_vocabulary:namespace rdf:type owl:AnnotationProperty . ### http://bio2rdf.org/bio2rdf_vocabulary:uri rdf:type owl:AnnotationProperty . ### http://data.bioontology.org/metadata/treeView rdf:type owl:AnnotationProperty . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl rdf:type owl:AnnotationProperty . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#NHC0 rdf:type owl:AnnotationProperty ; "NHC0" ; "Conceptual Entity" ; "code" ; "code" ; "A property representing a concept unique identifier within the NCI Enterprise Vocabulary Service's NCI Thesaurus." ; "true" ; rdfs:label "code" ; :disnetLabel "Code" ; rdfs:range xsd:string . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P106 rdf:type owl:AnnotationProperty ; "P106" ; "Conceptual Entity" ; "Semantic Type" ; "Semantic_Type" ; "Semantic_Type" ; "A property that represents a description of the sort of thing or category to which a concept belongs in the context of the UMLS semantic network." ; "In general, applying semantic types aids in allowing users (or computer programs) to draw conclusions about concepts by virtue of the categories to which they have been assigned. We use a set of semantic types developed for the UMLS Metathesaurus. There are currently 134 semantic types in the UMLS." ; rdfs:label "Semantic_Type" ; :disnetLabel "Semantic Type" . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P107 rdf:type owl:AnnotationProperty ; "P107" ; "Conceptual Entity" ; "Display Name" ; "Display_Name" ; "Display Name" , "Display_Name" ; "A property representing an alternative Preferred Name for use in some NCI systems." ; rdfs:label "Display_Name" ; :disnetLabel "Display Name" ; rdfs:range xsd:string . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P108 rdf:type owl:AnnotationProperty ; "P108" ; "Conceptual Entity" ; "Preferred Name" ; "Preferred_Name" ; "Preferred Name" , "Preferred Term" , "Preferred_Name" ; "A property representing the word or phrase that NCI uses by preference to refer to the concept." ; rdfs:label "Preferred_Name" ; :disnetLabel "Preferred Name" ; rdfs:range xsd:string . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P322 rdf:type owl:AnnotationProperty ; "P322" ; "Conceptual Entity" ; "Contributing Source" ; "Contributing_Source" ; "Contributing_Source" ; "A property is used to indicate when a non-EVS entity has contributed to, and has a stake in, a concept. This is used where such entities, within or outside NCI, have indicated the need to be able to track their own concepts. A single concept can have multiple instances of this property if multiple entities have such a defined stake." ; rdfs:label "Contributing_Source" ; :disnetLabel "Contributing Source" . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P325 rdf:type owl:AnnotationProperty ; "P325" ; "Conceptual Entity" ; "[source] Definition" ; "ALT_DEFINITION" ; "ALT_DEFINITION" ; "A property representing the English language definition of a concept from a source other than NCI." ; rdfs:label "ALT_DEFINITION" ; :disnetLabel "Alternative Definition" . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P384 rdf:type owl:AnnotationProperty ; "P384" ; "Conceptual Entity" ; "term-source" ; "A property representing the organization that is the supplier or owner of each FULL_SYN term." ; "true"^^xsd:boolean ; rdfs:label "Term Source" ; :disnetLabel "Term Source" . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P90 rdf:type owl:AnnotationProperty ; "P90" ; "Conceptual Entity" ; "Term & Source Data" ; "FULL_SYN" ; "FULL_SYN" , "Synonym with Source Data" ; "A property representing a fully qualified synonym, contains the string, term type, source, and an optional source code if appropriate. Each subfield is deliniated to facilitate interpretation by software." ; rdfs:label "FULL_SYN" ; :disnetLabel "Full Synonym" . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P97 rdf:type owl:AnnotationProperty ; "P97" ; "Conceptual Entity" ; "Definition" ; "DEFINITION" ; "DEFINITION" ; "A property representing the English language definitions of what NCI means by the concept. They may also include information about the definition's source and attribution in a form that can easily be interpreted by software." ; rdfs:label "DEFINITION" ; :disnetLabel "Definition" . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#P98 rdf:type owl:AnnotationProperty ; "P98" ; "Conceptual Entity" ; "DesignNote" ; "DesignNote" ; "DesignNote" ; "A property representing notations made by NCI vocabulary curators. They are intended to provide supplemental, unstructured information to the user or additional insight about the concept." ; rdfs:label "DesignNote" ; :disnetLabel "Design Note" ; rdfs:range xsd:string . [ rdf:type owl:Axiom ; owl:annotatedSource ; owl:annotatedProperty ; owl:annotatedTarget "DesignNote" ; "NCI" ] . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#default rdf:type owl:AnnotationProperty ; :disnetLabel "Default" ; rdfs:range xsd:string . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#required rdf:type owl:AnnotationProperty ; rdfs:range xsd:boolean . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#xref-source rdf:type owl:AnnotationProperty ; "A property representing the name of the organization to which an NCI Thesaurus concept is being linked to by cross reference." ; rdfs:label "xRef Source" ; :disnetLabel "XRef Source" . ### http://protege.stanford.edu/plugins/owl/protege#defaultLanguage rdf:type owl:AnnotationProperty . ### http://protege.stanford.edu/plugins/owl/protege#readOnly rdf:type owl:AnnotationProperty ; rdfs:range xsd:boolean . ### http://purl.obolibrary.org/obo/IAO_0000115 rdf:type owl:AnnotationProperty ; rdfs:label "definition" ; :disnetLabel "OBO Definition" . ### http://purl.org/dc/elements/1.1/date rdf:type owl:AnnotationProperty . ### http://purl.org/dc/elements/1.1/description rdf:type owl:AnnotationProperty . ### http://purl.org/dc/elements/1.1/identifier rdf:type owl:AnnotationProperty . ### http://purl.org/dc/terms/alternative rdf:type owl:AnnotationProperty . ### http://purl.org/dc/terms/contributor rdf:type owl:AnnotationProperty . ### http://purl.org/dc/terms/created rdf:type owl:AnnotationProperty . ### http://purl.org/dc/terms/creator rdf:type owl:AnnotationProperty . ### http://purl.org/dc/terms/description rdf:type owl:AnnotationProperty . ### http://purl.org/dc/terms/identifier rdf:type owl:AnnotationProperty . ### http://purl.org/dc/terms/license rdf:type owl:AnnotationProperty . ### http://purl.org/dc/terms/title rdf:type owl:AnnotationProperty . ### http://purl.org/vocab/vann/preferredNamespacePrefix rdf:type owl:AnnotationProperty . ### http://purl.org/vocab/vann/preferredNamespaceUri rdf:type owl:AnnotationProperty . ### http://rdfs.org/ns/void#inDataset rdf:type owl:AnnotationProperty . ### http://semanticscience.org/resource/equivalentTo rdf:type owl:AnnotationProperty ; :disnetLabel "Equivalent To" . ### http://semanticscience.org/resource/subset rdf:type owl:AnnotationProperty . ### http://www.ebi.ac.uk/efo/definition rdf:type owl:AnnotationProperty . ### http://www.geneontology.org/formats/oboInOwl#hasDbXref rdf:type owl:AnnotationProperty ; "A property representing a reference to an identical or very similar object in another database." ; rdfs:label "database_cross_reference" , "xRef" ; :disnetLabel "Database Cross Reference" . ### http://www.geneontology.org/formats/oboInOwl#hasExactSynonym rdf:type owl:AnnotationProperty ; rdfs:label "has_exact_synonym" ; :disnetLabel "Has Exact Synonym" . ### http://www.geneontology.org/formats/oboInOwl#hasOBONamespace rdf:type owl:AnnotationProperty ; rdfs:label "has_obo_namespace" ; :disnetLabel "Has OBO Namespace" . ### http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym rdf:type owl:AnnotationProperty ; rdfs:label "has_related_synonym" ; :disnetLabel "Has Related Synonym" . ### http://www.geneontology.org/formats/oboInOwl#hasSynonymType rdf:type owl:AnnotationProperty ; rdfs:label "has_synonym_type" ; :disnetLabel "Has Synonym Type" . ### http://www.geneontology.org/formats/oboInOwl#id rdf:type owl:AnnotationProperty ; :disnetLabel "OBO ID" . ### http://www.w3.org/2000/01/rdf-schema#label rdfs:label rdfs:label "label" . ### http://www.w3.org/2002/07/owl#versionIRI owl:versionIRI rdf:type owl:AnnotationProperty . ### http://www.w3.org/2004/02/skos/core#altLabel rdf:type owl:AnnotationProperty . ### http://www.w3.org/2004/02/skos/core#definition rdf:type owl:AnnotationProperty . ### http://www.w3.org/2004/02/skos/core#exactMatch rdf:type owl:AnnotationProperty . ### http://www.w3.org/2004/02/skos/core#example rdf:type owl:AnnotationProperty . ### http://www.w3.org/2004/02/skos/core#inScheme rdf:type owl:AnnotationProperty . ### http://www.w3.org/2004/02/skos/core#notation rdf:type owl:AnnotationProperty . ### http://www.w3.org/2004/02/skos/core#prefLabel rdf:type owl:AnnotationProperty ; rdfs:comment "A resource has no more than one value of skos:prefLabel per language tag, and no more than one value of skos:prefLabel without language tag."@en , "The range of skos:prefLabel is the class of RDF plain literals."@en , """skos:prefLabel, skos:altLabel and skos:hiddenLabel are pairwise disjoint properties."""@en ; rdfs:isDefinedBy ; rdfs:label "preferred label"@en ; "The preferred lexical label for a resource, in a given language."@en ; rdfs:subPropertyOf rdfs:label . ### http://xmlns.com/foaf/0.1/homepage rdf:type owl:AnnotationProperty . ### https://w3id.org/eboca/sem-disnet#disnetLabel :disnetLabel rdf:type owl:AnnotationProperty ; rdfs:label "Disnet Label" ; :disnetLabel "Disnet Label" . ################################################################# # Object Properties ################################################################# ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#R178 rdf:type owl:ObjectProperty ; owl:inverseOf ; rdfs:domain ; rdfs:range ; "R178" ; "Conceptual Entity" ; "Gene_Mutant_Encodes_Gene_Product_Sequence_Variation" ; "Gene_Mutant_Encodes_Gene_Product_Sequence_Variation" ; "A role used to indicate that a specific molecular variation or mutation in a gene encodes a gene product sequence variant. The domain and range for this role are 'Gene Mutant' and 'Gene Product Sequence Variation', respectively." ; rdfs:label "Gene_Mutant_Encodes_Gene_Product_Sequence_Variation" ; :disnetLabel "Gene Associated With Variant" . [ rdf:type owl:Axiom ; owl:annotatedSource ; owl:annotatedProperty ; owl:annotatedTarget "Gene_Mutant_Encodes_Gene_Product_Sequence_Variation" ; "NCI" ] . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#R41 rdf:type owl:ObjectProperty ; rdfs:domain ; rdfs:range ; "R41" ; "Conceptual Entity" ; "Found In Organism" ; "Gene_Found_In_Organism" ; "Gene_Found_In_Organism" ; "A role used to specify the organism of origin for a gene. It may be used to differentiate genes with the same name and functions that originate from different organisms. The domain and range for this role are 'Gene' and 'Organism', respectively." ; "Currently, we only model human genes, but this role has obvious utility in future, if other organisms are modeled as well." ; rdfs:label "Gene_Found_In_Organism" ; :disnetLabel "Gene In Organism" . [ rdf:type owl:Axiom ; owl:annotatedSource ; owl:annotatedProperty ; owl:annotatedTarget "Gene_Found_In_Organism" ; "NCI" ] . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#R45 rdf:type owl:ObjectProperty ; rdfs:domain ; rdfs:range ; "R45" ; "Conceptual Entity" ; "Has Organism Source" ; "Gene_Product_Has_Organism_Source" ; "Gene_Product_Has_Organism_Source" ; "A role used to differentiate homologous proteins from different organisms. The domain and range for this role are 'Gene Product' and 'Organism', respectively." ; rdfs:label "Gene_Product_Has_Organism_Source" ; :disnetLabel "Protein In Organism" . [ rdf:type owl:Axiom ; owl:annotatedSource ; owl:annotatedProperty ; owl:annotatedTarget "Gene_Product_Has_Organism_Source" ; "NCI" ] . ### http://purl.bioontology.org/ontology/SNOMEDCT/causative_agent_of rdf:type owl:ObjectProperty ; owl:inverseOf ; rdfs:label "Causative agent of" ; :disnetLabel "Causative agent of" . ### http://purl.bioontology.org/ontology/SNOMEDCT/cause_of rdf:type owl:ObjectProperty ; owl:inverseOf ; rdfs:label "Cause of" ; :disnetLabel "Cause Of" . ### http://purl.bioontology.org/ontology/SNOMEDCT/due_to rdf:type owl:ObjectProperty ; rdfs:label "Due to" ; :disnetLabel "Due To" . ### http://purl.bioontology.org/ontology/SNOMEDCT/has_causative_agent rdf:type owl:ObjectProperty ; rdfs:label "Has causative agent" ; :disnetLabel "Has causative agent" . ### http://rdf.ebi.ac.uk/terms/chembl#hasDrugIndication rdf:type owl:ObjectProperty ; "Association between the entity and a ChEMBL Drug Indication" ; rdfs:label "ChEMBL Drug Indication Association" ; "ChEMBL Drug Indication Association" ; :disnetLabel "ChEMBL Has Drug Indication" . ### http://rdf.ebi.ac.uk/terms/chembl#hasMechanism rdf:type owl:ObjectProperty ; owl:inverseOf ; "Association between the entity and a ChEMBL Mechanism of Action" ; rdfs:label "ChEMBL Mechanism Association" ; "ChEMBL Mechanism Association" ; :disnetLabel "ChEMBL Has Drug Target" . ### http://rdf.ebi.ac.uk/terms/chembl#hasMolecule rdf:type owl:ObjectProperty ; "Association between the entity and a ChEMBL Molecule" ; rdfs:label "ChEMBL Molecule Association" ; "ChEMBL Molecule Association" ; :disnetLabel "ChEMBL Has Drug" . ### http://rdf.ebi.ac.uk/terms/chembl#hasTarget rdf:type owl:ObjectProperty ; owl:inverseOf ; "Association between the entity and a ChEMBL Target" ; rdfs:label "ChEMBL Target Association" ; "ChEMBL Target Association" ; :disnetLabel "ChEMBL Has Target" . ### http://rdf.ebi.ac.uk/terms/chembl#isTargetForMechanism rdf:type owl:ObjectProperty ; "" ; rdfs:label "Association between ChEMBL Target and Mechanism " ; "Association between ChEMBL Target and Mechanism " ; :disnetLabel "Is Target" . ### http://semanticscience.org/resource/SIO_000008 rdf:type owl:ObjectProperty ; owl:inverseOf ; rdfs:domain [ rdf:type owl:Class ; owl:unionOf ( :Phenotype ) ] ; rdfs:range [ rdf:type owl:Class ; owl:unionOf ( ) ] ; "SIO_000008" ; "has attribute is a relation that associates a entity with an attribute where an attribute is an intrinsic characteristic such as a quality, capability, disposition, function, or is an externally derived attribute determined from some descriptor (e.g. a quantity, position, label/identifier) either directly or indirectly through generalization of entities of the same type."@en ; "core" ; rdfs:isDefinedBy ; rdfs:label "has attribute"@en ; :disnetLabel "Has Attribute" . ### http://semanticscience.org/resource/SIO_000011 rdf:type owl:ObjectProperty ; rdfs:domain [ rdf:type owl:Class ; owl:unionOf ( ) ] ; rdfs:range [ rdf:type owl:Class ; owl:unionOf ( :Phenotype ) ] ; "SIO_000011" ; "is attribute of is a relation that associates an attribute with an entity where an attribute is an intrinsic characteristic such as a quality, capability, disposition, function, or is an externally derived attribute determined from some descriptor (e.g. a quantity, position, label/identifier) either directly or indirectly through generalization of entities of the same type."@en ; rdfs:isDefinedBy ; rdfs:label "is attribute of"@en ; :disnetLabel "Is Attribute Of" . ### http://semanticscience.org/resource/SIO_000028 rdf:type owl:ObjectProperty ; rdfs:subPropertyOf ; owl:inverseOf ; rdfs:domain [ rdf:type owl:Class ; owl:unionOf ( ) ] ; rdfs:range [ rdf:type owl:Class ; owl:unionOf ( ) ] ; "SIO_000028" ; "has part is a transitive, reflexive and antisymmetric relation between a whole and itself or a whole and its part."@en ; rdfs:isDefinedBy ; rdfs:label "has part"@en ; "a collection of cars has as a car as a part;a car has an engine as a part; a car has a piston as a part;"@en ; :disnetLabel "Has Part" . ### http://semanticscience.org/resource/SIO_000059 rdf:type owl:ObjectProperty ; rdfs:subPropertyOf ; owl:inverseOf ; rdf:type owl:IrreflexiveProperty ; rdfs:domain [ rdf:type owl:Class ; owl:unionOf ( ) ] ; rdfs:range [ rdf:type owl:Class ; owl:unionOf ( ) ] ; "SIO_000059" ; "has member is a mereological relation between a collection and an item."@en ; "core" ; rdfs:isDefinedBy ; rdfs:label "has member"@en ; "a collection of cars has as a car as a member"@en ; :disnetLabel "Has Member" . ### http://semanticscience.org/resource/SIO_000061 rdf:type owl:ObjectProperty ; owl:inverseOf ; rdfs:domain ; rdfs:range [ rdf:type owl:Class ; owl:unionOf ( ) ] ; "SIO_000061" ; "A is located in B iff the spatialtemporial region occupied by A is part of the spatialtemporal region occupied by B. [T][R]"@en ; "OBO_REL:located_in" ; "core" ; rdfs:isDefinedBy ; rdfs:label "is located in"@en ; "A parasite in the interior of a person's intestine is located in their intestinal lumen."@en ; :disnetLabel "Is Located In" . ### http://semanticscience.org/resource/SIO_000062 rdf:type owl:ObjectProperty ; owl:inverseOf ; rdfs:domain [ rdf:type owl:Class ; owl:unionOf ( ) ] ; rdfs:range [ rdf:type owl:Class ; owl:unionOf ( ) ] ; "SIO_000062" ; "is participant in is a relation that describes the participation of the subject in the (processual) object."@en ; rdfs:isDefinedBy ; rdfs:label "is participant in"@en ; "a car is a participant in a car race; glucose is a participant in glycolysis"@en ; :disnetLabel "Is Participant In" . ### http://semanticscience.org/resource/SIO_000068 rdf:type owl:ObjectProperty ; rdfs:subPropertyOf ; rdfs:domain [ rdf:type owl:Class ; owl:unionOf ( ) ] ; rdfs:range [ rdf:type owl:Class ; owl:unionOf ( ) ] ; "SIO_000068" ; "is part of is a transitive, reflexive and anti-symmetric mereological relation between a whole and itself or a part and its whole."@en ; "OBO_REL:part_of" ; "core" ; rdfs:isDefinedBy ; rdfs:label "is part of"@en ; :disnetLabel "Is Part Of" . ### http://semanticscience.org/resource/SIO_000095 rdf:type owl:ObjectProperty ; rdfs:subPropertyOf ; rdfs:domain [ rdf:type owl:Class ; owl:unionOf ( ) ] ; rdfs:range [ rdf:type owl:Class ; owl:unionOf ( ) ] ; "SIO_000095" ; "is member of is a mereological relation between a item and a collection."@en ; rdfs:isDefinedBy ; rdfs:label "is member of"@en ; :disnetLabel "Is Member Of" . ### http://semanticscience.org/resource/SIO_000132 rdf:type owl:ObjectProperty ; rdfs:domain [ rdf:type owl:Class ; owl:unionOf ( ) ] ; rdfs:range [ rdf:type owl:Class ; owl:unionOf ( ) ] ; "SIO_000132" ; "has participant is a relation that describes the participation of the object in the (processual) subject."@en ; "OBO_REL:has_participant" ; "core" ; rdfs:isDefinedBy ; rdfs:label "has participant"@en ; :disnetLabel "Has Participant" . ### http://semanticscience.org/resource/SIO_000145 rdf:type owl:ObjectProperty ; rdfs:domain [ rdf:type owl:Class ; owl:unionOf ( ) ] ; rdfs:range ; "SIO_000145" ; "A is location of B iff the spatialtemporal region occupied by A has the spatialtemporal region occupied by B as a part. [T][R]"@en ; "nlp+" ; rdfs:isDefinedBy ; rdfs:label "is location of"@en ; :disnetLabel "Is Location Of" . ### http://semanticscience.org/resource/SIO_000205 rdf:type owl:ObjectProperty ; rdfs:subPropertyOf ; owl:inverseOf ; rdfs:domain ; rdfs:range ; "SIO_000205" ; "is represented by: a relation between an entity and some symbol."@en ; rdfs:isDefinedBy ; rdfs:label "is represented by"@en ; :disnetLabel "Is Represented By" . ### http://semanticscience.org/resource/SIO_000210 rdf:type owl:ObjectProperty ; rdfs:subPropertyOf ; rdfs:domain ; rdfs:range ; "SIO_000210" ; "a represents b when a serves as a sign, symbol or model of b."@en ; "core" ; rdfs:isDefinedBy ; rdfs:label "represents"@en ; :disnetLabel "Represents" . ### http://semanticscience.org/resource/SIO_000212 rdf:type owl:ObjectProperty ; owl:inverseOf ; rdfs:domain [ rdf:type owl:Class ; owl:unionOf ( :Phenotype ) ] ; rdfs:range [ rdf:type owl:Class ; owl:unionOf ( :DiseaseNcrna :DiseasePhenotype :DrugDisease :Prevalence ) ] ; "SIO_000212" ; "A is referred to by B iff B is an informational entity that makes reference to A."@en ; rdfs:isDefinedBy ; rdfs:label "is referred to by"@en ; :disnetLabel "Is Referred To By" . ### http://semanticscience.org/resource/SIO_000215 rdf:type owl:ObjectProperty ; rdfs:subPropertyOf ; owl:inverseOf ; rdfs:domain [ rdf:type owl:Class ; owl:unionOf ( ) ] ; rdfs:range [ rdf:type owl:Class ; owl:unionOf ( ) ] ; "SIO_000215" ; "is measurement value of is a relation between a value and the entity that it is a measurement of."@en ; rdfs:isDefinedBy ; rdfs:label "is measurement value of"@en ; :disnetLabel "Is Measurement Value Of" . ### http://semanticscience.org/resource/SIO_000216 rdf:type owl:ObjectProperty ; rdfs:subPropertyOf ; rdfs:domain [ rdf:type owl:Class ; owl:unionOf ( ) ] ; rdfs:range [ rdf:type owl:Class ; owl:unionOf ( ) ] ; "SIO_000216" ; "has measurement value is a relation between a quality/realizable and a measurement value."@en ; "core" ; rdfs:isDefinedBy ; rdfs:label "has measurement value"@en ; :disnetLabel "Has Measurement Value" . ### http://semanticscience.org/resource/SIO_000291 rdf:type owl:ObjectProperty ; owl:inverseOf ; rdfs:domain [ rdf:type owl:Class ; owl:unionOf ( ) ] ; rdfs:range ; "SIO_000291" ; "has target is a relation between a process and an entity, where the entity is present at the beginning of the process and undergoes a change or transformation in the process."@en ; rdfs:isDefinedBy ; rdfs:label "has target"@en ; :disnetLabel "Has Target" . ### http://semanticscience.org/resource/SIO_000292 rdf:type owl:ObjectProperty ; rdfs:domain ; rdfs:range [ rdf:type owl:Class ; owl:unionOf ( ) ] ; "SIO_000292" ; "is target in is a relation between an entity and a process, where the entity is present at the beginning of the process and undergoes a change or transformation in the process."@en ; rdfs:isDefinedBy ; rdfs:label "is target in"@en ; "glucose is a target in the hexokinase-mediated conversion of glucose to glucose-6-phosphate."@en ; :disnetLabel "Is Target In" . ### http://semanticscience.org/resource/SIO_000628 rdf:type owl:ObjectProperty ; rdfs:domain [ rdf:type owl:Class ; owl:unionOf ( :DiseaseNcrna :DiseasePhenotype :DrugDisease :Prevalence ) ] ; rdfs:range [ rdf:type owl:Class ; owl:unionOf ( :Phenotype ) ] ; "SIO_000628" ; "refers to is a relation between one entity and the entity that it makes reference to."@en ; "core" , "nlp+" ; rdfs:isDefinedBy ; rdfs:label "refers to"@en ; :disnetLabel "Refers To" . ### http://semanticscience.org/resource/SIO_001403 rdf:type owl:ObjectProperty ; rdfs:domain ; rdfs:range ; "x is associated with y when x and y are logically or statistically related to one another."@en ; "SIO_001403" ; rdfs:isDefinedBy ; rdfs:label "is associated with"@en ; :disnetLabel "Is Associated With" . ### http://semanticscience.org/resource/SIO_010078 rdf:type owl:ObjectProperty ; owl:inverseOf ; rdfs:domain ; rdfs:range ; "SIO_010078" ; "A relation between two objects, in which the first object contains information that is used to produce the second object."@en ; rdfs:isDefinedBy ; rdfs:label "encodes"@en ; "an open reading frame encodes a protein (it contains information that specifies the amino acid composition and topology)"@en ; :disnetLabel "Encodes" . ### http://semanticscience.org/resource/SIO_010079 rdf:type owl:ObjectProperty ; rdfs:domain ; rdfs:range ; "SIO_010079" ; "A relation between two objects, in which the first object is produced from the information contained in the second object."@en ; rdfs:isDefinedBy ; rdfs:label "is encoded by"@en ; :disnetLabel "Is Encoded By" . ### https://w3id.org/eboca/sem-disnet#drugForDrugIndication :drugForDrugIndication rdf:type owl:ObjectProperty ; rdfs:subPropertyOf , ; owl:inverseOf :indicationHasMolecule ; rdfs:domain ; rdfs:range :DrugPhenotypeIndication ; rdfs:label "Drug For Drug-Phenotype Indication" ; :disnetLabel "Drug For Drug Phenotype Indication" . ### https://w3id.org/eboca/sem-disnet#drugForMechanism :drugForMechanism rdf:type owl:ObjectProperty ; rdfs:subPropertyOf , ; owl:inverseOf :mechanismHasMolecule ; rdfs:domain ; rdfs:range :DrugTarget ; rdfs:label "Drug For Drug-Target Association" ; :disnetLabel "Drug For Drug Target Association" . ### https://w3id.org/eboca/sem-disnet#drugForSideEffect :drugForSideEffect rdf:type owl:ObjectProperty ; rdfs:subPropertyOf , ; owl:inverseOf :sideEffectHasMolecule ; rdfs:domain ; rdfs:range :DrugPhenotypeSideEffect ; rdfs:label "Drug For Drug-Phenotype Side Effect" ; :disnetLabel "Drug For Drug-Phenotype Side Effect" . ### https://w3id.org/eboca/sem-disnet#hasPhenotype :hasPhenotype rdf:type owl:ObjectProperty ; rdfs:subPropertyOf , ; owl:inverseOf :phenotypeForSideEffect ; rdfs:domain :DrugPhenotypeSideEffect ; rdfs:range :Phenotype ; rdfs:label "Drug-Phenotype Side Effect Has Phenotype" ; :disnetLabel "Drug-Phenotype Side Effect Has Phenotype" . ### https://w3id.org/eboca/sem-disnet#hasSideEffect :hasSideEffect rdf:type owl:ObjectProperty ; owl:inverseOf :isSideEffect ; rdfs:domain ; rdfs:range :Phenotype ; rdfs:label "DDI Has Side Effect" ; :disnetLabel "DDI Has Side Effect" . ### https://w3id.org/eboca/sem-disnet#hasTarget :hasTarget rdf:type owl:ObjectProperty ; rdfs:subPropertyOf , ; owl:inverseOf :targetForMechanism ; rdfs:domain :DrugTarget ; rdfs:range ; rdfs:label "Drug-Target Has Target" ; :disnetLabel "Drug-Target Has Target" . ### https://w3id.org/eboca/sem-disnet#indicationHasMolecule :indicationHasMolecule rdf:type owl:ObjectProperty ; rdfs:subPropertyOf , ; rdfs:domain :DrugPhenotypeIndication ; rdfs:range ; rdfs:label "Indication Has Drug" ; :disnetLabel "Indication Has Drug" . ### https://w3id.org/eboca/sem-disnet#isSideEffect :isSideEffect rdf:type owl:ObjectProperty ; rdfs:domain :Phenotype ; rdfs:range ; rdfs:label "Phenotype Side Effect Due To DDI" ; :disnetLabel "Phenotype Side Effect Due To DDI" . ### https://w3id.org/eboca/sem-disnet#mechanismHasMolecule :mechanismHasMolecule rdf:type owl:ObjectProperty ; rdfs:subPropertyOf , ; rdfs:domain :DrugTarget ; rdfs:range ; rdfs:label "Drug-Target Association Has Drug" ; :disnetLabel "Drug-Target Association Has Drug" . ### https://w3id.org/eboca/sem-disnet#phenotypeForSideEffect :phenotypeForSideEffect rdf:type owl:ObjectProperty ; rdfs:subPropertyOf , ; rdfs:domain :Phenotype ; rdfs:range :DrugPhenotypeSideEffect ; rdfs:label "Phenotype For Drug-Phenotype Side Effect" ; :disnetLabel "Phenotype For Drug-Phenotype Side Effect" . ### https://w3id.org/eboca/sem-disnet#sideEffectHasMolecule :sideEffectHasMolecule rdf:type owl:ObjectProperty ; rdfs:subPropertyOf , ; rdfs:domain :DrugPhenotypeSideEffect ; rdfs:range ; rdfs:label "Side Effect Has Drug" ; :disnetLabel "Side Effect Has Drug" . ### https://w3id.org/eboca/sem-disnet#targetForMechanism :targetForMechanism rdf:type owl:ObjectProperty ; rdfs:subPropertyOf , ; rdfs:domain ; rdfs:range :DrugTarget ; rdfs:label "Target For Drug-Target Association" ; :disnetLabel "Is Target For Drug Target Association" . ################################################################# # Data properties ################################################################# ### http://rdf.ebi.ac.uk/terms/chembl#atcClassification rdf:type owl:DatatypeProperty ; rdfs:domain ; rdfs:range xsd:string ; "ATC Classification Code" ; rdfs:label "ATC Code" ; "ATC Code" ; :disnetLabel "ATC Code" . ### http://rdf.ebi.ac.uk/terms/chembl#chemblId rdf:type owl:DatatypeProperty ; rdfs:domain [ rdf:type owl:Class ; owl:unionOf ( :DrugPhenotypeIndication :DrugPhenotypeSideEffect ) ] ; rdfs:range xsd:string ; "" ; rdfs:label "The ChEMBL ID for a given entity" ; "The ChEMBL ID for a given entity" ; :disnetLabel "CHEMBL ID" . ### http://rdf.ebi.ac.uk/terms/chembl#highestDevelopmentPhase rdf:type owl:DatatypeProperty ; rdfs:domain [ rdf:type owl:Class ; owl:unionOf ( :DrugPhenotypeIndication :DrugPhenotypeSideEffect ) ] ; rdfs:range xsd:integer ; "The highest phase the molecule has reached in drug approval process (4 = approved)" ; rdfs:label "ChEMBL Molecule Development Phase" ; "ChEMBL Molecule Development Phase" ; :disnetLabel "Highest Development Phase" . ### http://rdf.ebi.ac.uk/terms/chembl#mechanismActionType rdf:type owl:DatatypeProperty ; rdfs:domain :DrugTarget ; rdfs:range xsd:string ; "Type of action of the drug on the target e.g., agonist/antagonist etc (foreign key to action_type table)" ; rdfs:label "ChEMBL Mechanism Action Type" ; "ChEMBL Mechanism Action Type" ; :disnetLabel "Drug Target Action Type" . ### http://rdf.ebi.ac.uk/terms/chembl#proteinSequence rdf:type owl:DatatypeProperty ; rdfs:domain ; rdfs:range xsd:string ; "Protein sequence for given ChEMBL entity" ; rdfs:label "Protein sequence for given ChEMBL entity" ; "Protein sequence for given ChEMBL entity" ; :disnetLabel "Protein Sequence" . ### http://rdf.ebi.ac.uk/terms/chembl#substanceType rdf:type owl:DatatypeProperty ; rdfs:domain ; rdfs:range xsd:string ; "ChEMBL Substance Entity Type" ; rdfs:label "ChEMBL Substance Entity Type" ; "ChEMBL Substance Entity Type" . ### http://rdf.ebi.ac.uk/terms/chembl#targetType rdf:type owl:DatatypeProperty ; rdfs:domain ; rdfs:range xsd:string ; "Describes whether target is a protein, an organism, a tissue etc." ; rdfs:label "ChEMBL Target Entity Type" ; "ChEMBL Target Entity Type" . ### http://semanticscience.org/resource/SIO_000300 rdf:type owl:DatatypeProperty , owl:FunctionalProperty ; rdfs:domain [ rdf:type owl:Class ; owl:unionOf ( :DrugDisease ) ] ; rdfs:range [ rdf:type rdfs:Datatype ; owl:unionOf ( xsd:double xsd:integer xsd:string ) ] ; "SIO_000300" ; "A relation between a informational entity and its actual value (numeric, date, text, etc)."@en ; "sadi"@en , "core" , "nlp" , "relations" ; rdfs:isDefinedBy ; rdfs:label "has value"@en ; :disnetLabel "Has Value" . ### https://w3id.org/eboca/sem-disnet#category :category rdf:type owl:DatatypeProperty ; rdfs:domain :DiseaseNcrna ; rdfs:range xsd:string ; rdfs:label "Category" ; :disnetLabel "Category" . ### https://w3id.org/eboca/sem-disnet#causality :causality rdf:type owl:DatatypeProperty ; rdfs:domain :DiseaseNcrna ; rdfs:range xsd:string ; rdfs:label "Causality" ; :disnetLabel "Causality" . ### https://w3id.org/eboca/sem-disnet#chemicalStructure :chemicalStructure rdf:type owl:DatatypeProperty ; rdfs:domain ; rdfs:range xsd:string ; rdfs:label "Chemical Structure" ; :disnetLabel "Chemical Structure" . ### https://w3id.org/eboca/sem-disnet#chrVersion :chrVersion rdf:type owl:DatatypeProperty ; rdfs:domain ; rdfs:range xsd:string ; rdfs:label "Chromosome No Version" ; :disnetLabel "Chromosome Version" . ### https://w3id.org/eboca/sem-disnet#concentration :concentration rdf:type owl:DatatypeProperty ; rdfs:domain ; rdfs:range xsd:string ; rdfs:label "Concentration" ; :disnetLabel "Marker Concentration" . ### https://w3id.org/eboca/sem-disnet#confidenceValue :confidenceValue rdf:type owl:DatatypeProperty ; rdfs:domain :Ppi ; rdfs:range xsd:string ; rdfs:label "Confidence Value" ; :disnetLabel "PPI Confidence Value" . ### https://w3id.org/eboca/sem-disnet#consequence :consequence rdf:type owl:DatatypeProperty ; rdfs:domain ; rdfs:range xsd:string ; rdfs:label "Consequence" ; :disnetLabel "Variant Consequence" . ### https://w3id.org/eboca/sem-disnet#geneSequence :geneSequence rdf:type owl:DatatypeProperty ; rdfs:domain ; rdfs:range xsd:string ; rdfs:label "Gene Sequence" ; :disnetLabel "Gene Sequence" . ### https://w3id.org/eboca/sem-disnet#geo :geo rdf:type owl:DatatypeProperty ; rdfs:domain :Prevalence ; rdfs:range xsd:string ; rdfs:label "Geography" ; :disnetLabel "Geography" . ### https://w3id.org/eboca/sem-disnet#inchiKey :inchiKey rdf:type owl:DatatypeProperty ; rdfs:domain ; rdfs:range xsd:string ; rdfs:label "Inchi Key" ; :disnetLabel "Inchi Key" . ### https://w3id.org/eboca/sem-disnet#rnaCategory :rnaCategory rdf:type owl:DatatypeProperty ; rdfs:domain ; rdfs:range xsd:string ; rdfs:label "ncRNA Category" ; :disnetLabel "ncRNA Category" . ### https://w3id.org/eboca/sem-disnet#sample :sample rdf:type owl:DatatypeProperty ; rdfs:domain ; rdfs:range xsd:string ; rdfs:label "Sample" ; :disnetLabel "Marker Sample" . ### https://w3id.org/eboca/sem-disnet#seqEnd :seqEnd rdf:type owl:DatatypeProperty ; rdfs:domain ; rdfs:range xsd:integer ; rdfs:label "Sequence end position" ; :disnetLabel "Sequence End Position" . ### https://w3id.org/eboca/sem-disnet#seqStart :seqStart rdf:type owl:DatatypeProperty ; rdfs:domain ; rdfs:range xsd:integer ; rdfs:label "Sequence start position" ; :disnetLabel "Sequence Start Position" . ### https://w3id.org/eboca/sem-disnet#strand :strand rdf:type owl:DatatypeProperty ; rdfs:domain ; rdfs:range xsd:integer ; rdfs:label "Strand" ; :disnetLabel "Strand" . ### https://w3id.org/eboca/sem-disnet#synonymous :synonymous rdf:type owl:DatatypeProperty ; rdfs:domain ; rdfs:range xsd:string ; rdfs:label "Synonymous" . ### https://w3id.org/eboca/sem-disnet#type :type rdf:type owl:DatatypeProperty ; rdfs:domain :DiseaseNcrna ; rdfs:range xsd:string ; rdfs:label "Disease-ncRNA Association type" . ################################################################# # Classes ################################################################# ### http://bio2rdf.org/ctd_vocabulary:Chemical-Disease-Association rdf:type owl:Class ; "Chemical-Disease-Association" ; "ctd_vocabulary" ; "http://bio2rdf.org/ctd_vocabulary:Chemical-Disease-Association" ; "ctd_vocabulary:Chemical-Disease-Association" ; "A CTD association between a chemical and a disease"@en ; ; rdfs:label "A CTD association between a chemical and a disease [ctd_vocabulary:Chemical-Disease-Association]"@en , "A CTD association between a chemical and a disease [ctd_vocabulary:Chemical-Disease-Association]" ; :disnetLabel "Drug Disease Associaton" . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T019 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T019" ; "Congenital Abnormality"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T019] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Congenital Abnormality [umls:T019]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T020 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T020" ; "Acquired Abnormality"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T020] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Acquired Abnormality [umls:T020]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T026 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T026" ; "Cell Component"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T026] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Cell Component [umls:T026]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T031 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T031" ; "Body Substance"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T031] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Body Substance [umls:T031]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T032 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T032" ; "Organism Attribute"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T032] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Organism Attribute [umls:T032]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T033 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T033" ; "Finding"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T033] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Finding [umls:T033]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T034 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T034" ; "Laboratory or Test Result"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T034] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Laboratory or Test Result [umls:T034]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T037 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T037" ; "Injury or Poisoning"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T037] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Injury or Poisoning [umls:T037]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T039 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T039" ; "Physiologic Function"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T039] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Physiologic Function [umls:T039]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T040 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T040" ; "Organism Function"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T040] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Organism Function [umls:T040]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T041 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T041" ; "Mental Process"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T041] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Mental Process [umls:T041]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T042 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T042" ; "Organ or Tissue Function"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T042] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Organ or Tissue Function [umls:T042]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T043 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T043" ; "Cell Function"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T043] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Cell Function [umls:T043]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T044 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T044" ; "Molecular Function"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T044] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Molecular Function [umls:T044]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T046 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T046" ; "Pathologic Function"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T046] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Pathologic Function [umls:T046]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T047 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T047" ; "Disease or Syndrome"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T047] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Disease or Syndrome [umls:T047]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T048 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T048" ; "Mental or Behavioral Dysfunction"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T048] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Mental or Behavioral Dysfunction [umls:T048]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T049 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T049" ; "Cell or Molecular Dysfunction"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T049] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Cell or Molecular Dysfunction [umls:T049]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T050 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T050" ; "Experimental Model of Disease"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T050] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Experimental Model of Disease [umls:T050]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T054 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T054" ; "Social Behavior"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T054] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Social Behavior [umls:T054]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T055 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T055" ; "Individual Behavior"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T055] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Individual Behavior [umls:T055]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T059 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T059" ; "Laboratory Procedure"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T059] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Laboratory Procedure [umls:T059]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T060 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T060" ; "Diagnostic Procedure"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T060] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Diagnostic Procedure [umls:T060]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T079 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T079" ; "Temporal Concept"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T079] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Temporal Concept [umls:T079]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T116 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T116" ; "Amino Acid, Peptide, or Protein"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T116] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Amino Acid, Peptide, or Protein [umls:T116]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T129 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T129" ; "Immunologic Factor"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T129] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Immunologic Factor [umls:T129]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T184 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T184" ; "Sign or Symptom"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T184] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Sign or Symptom [umls:T184]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T185 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T185" ; "Classification"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T185] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Classification [umls:T185]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T190 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T190" ; "Anatomical Abnormality"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T190] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Anatomical Abnormality [umls:T190]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T191 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T191" ; "Neoplastic Process"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T191] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Neoplastic Process [umls:T191]"@en ; , , ; . ### http://biotop.googlecode.com/svn/trunk/umlssn.owl#T201 rdf:type owl:Class ; rdfs:subClassOf ; "umls:T201" ; "Clinical Attribute"@en ; ; rdfs:comment "UMLS Semantic Type (STY) [umls:T201] annotated to at least one disease in DisGeNET. STYs are identified by the UMLS TUI."@en ; rdfs:isDefinedBy ; rdfs:label "Clinical Attribute [umls:T201]"@en ; , , ; . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C14250 rdf:type owl:Class ; "C14250" ; "Organism" ; "Organism" ; "BRIDG" , "NICHD" ; "A living thing, such as an animal, a plant, a bacterium, or a fungus." , "Any individual living (or previously living) being. EXAMPLE(S): animal, human being" ; "BiologicEntity" , "Organism" , "Organismal" , "Organisms" , "Taxon" , "organism" ; "A living entity." ; rdfs:label "Organism" ; :disnetLabel "Organism" . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16612 rdf:type owl:Class ; owl:disjointWith , ; "C16612" ; "Gene or Genome" ; "Gene" ; "BRIDG" ; "A functional unit of heredity that occupies a specific position (locus) on a particular chromosome, is capable of reproducing itself exactly at each cell division, and directs the formation of a protein or other product. Comment Requested: In interest of re-using existing standards, should the above definition of Gene be replaced by the following from the NLM - The basic physical and functional unit of heredity. It is made up of DNA and act as instructions to make molecules called proteins. [Source: http://ghr.nlm.nih.gov/handbook/basics/gene] EXAMPLE(S): BRCA1 gene OTHER NAME(S): NOTE(S):" , "The functional and physical unit of heredity passed from parent to offspring. Genes are pieces of DNA, and most genes contain the information for making a specific protein." ; "Gene" , "Genes" , "gene" ; "A functional unit of heredity which occupies a specific position on a particular chromosome and serves as the template for a product that contributes to a phenotype or a biological function." ; "The gene as a functional unit consists of a discrete segment of a giant DNA molecule containing the purine (adenine and guanine) and pyrimidine (cytosine and thymine) bases in the ordered and correct sequence that encodes a specific functional product (i.e., a protein or RNA molecule)." ; rdfs:label "Gene" ; :disnetLabel "Gene" . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17021 rdf:type owl:Class ; owl:disjointWith ; "C17021" ; "Amino Acid, Peptide, or Protein" ; "Protein" ; "BRIDG" , "GDC" ; "A molecule made up of amino acids that are needed for the body to function properly. Proteins are the basis of body structures such as skin and hair and of substances such as enzymes, cytokines, and antibodies." , "A representation of an organic macromolecule in public resources (e.g., UniProt or NCBI RefSeq) composed of one or more chains (linear polymers) of alpha-L-amino acids linked by peptide bonds and ranging in size from a few thousand to over 1 million Daltons. Comment Requested: In interest of re-using existing standards, should the above definition of Protein be replaced by the following from the NLM -- : A molecule made up of amino acids that are needed for the body to function properly. Proteins are the basis of body structures such as skin and hair and of substances such as enzymes, cytokines, and antibodies. [Source: http://ghr.nlm.nih.gov/glossary=protein] EXAMPLE(S): A protein record from UniProt Knowledgebase: http://www.uniprot.org/uniprot/P38398 OTHER NAME(S): NOTE(S):" ; "Protein" , "Protein (NOS)" , "Proteins" , "protein" ; "A group of complex organic macromolecules composed of one or more chains (linear polymers) of alpha-L-amino acids linked by peptide bonds and ranging in size from a few thousand to over 1 million Daltons. Proteins are fundamental genetically encoded components of living cells with specific structures and functions dictated by amino acid sequence." ; rdfs:label "Protein" ; :disnetLabel "Protein" . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18329 rdf:type owl:Class ; "C18329" ; "Indicator, Reagent, or Diagnostic Aid" ; "Disease Marker" ; "Disease Marker" , "Marker, Disease" , "Markers, Disease" ; "Specific molecular signature of disease, physiological measurement, genotype structural or functional characteristic, metabolic changes, or other determinant that may simplify the diagnostic process, make diagnoses more accurate, distinguish different causes of disease, or enable physicians to make diagnoses before symptoms appear and to track disease progression." ; rdfs:label "Disease Marker" ; :disnetLabel "Disease Marker" . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C18469 rdf:type owl:Class ; "C18469" ; "Molecular Function" ; "Protein-Protein Interaction" ; "Protein-Protein Interaction" ; "Temporary, non-covalent binding between protein molecules. Protein-protein interactions occur as a result of intermolecular physical forces and spatial complementation between domains or motifs. This interaction can be either homotypic or heterotypic and effect protein structure, conformation, and function." ; rdfs:label "Protein-Protein Interaction" ; :disnetLabel "PPI" . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C25338 rdf:type owl:Class ; owl:disjointWith , ; "C25338" ; "Quantitative Concept" ; "Score" ; "CDISC" ; "A number or range of numeric values that assess and order a result or response for purposes of comparison." ; "SCORE" , "Score" ; "A number or range of numeric values measuring performance, function, quality, or ability." ; rdfs:label "Score" ; :disnetLabel "Score" . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26549 rdf:type owl:Class ; owl:disjointWith ; "C26549" ; "Nucleic Acid, Nucleoside, or Nucleotide" ; "Untranslated RNA" ; "Functional RNA" , "Non-Coding RNA" , "Noncoding RNA" , "Untranslated RNA" , "ncRNA" ; "The product of so-called RNA genes; a functional RNA represents the final product of a gene rather than a transient molecule that will be translated into protein." ; rdfs:label "Untranslated RNA" ; :disnetLabel "ncRNA" . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C43568 rdf:type owl:Class ; "C43568" ; "Intellectual Product" ; "Gene Symbol" ; "BRIDG" , "CTDC" ; "A conventional sign used for representing the gene, based on the identified source. EXAMPLE(S): As a string with an optional code, an example of Gene.symbol is as follows: the value \"BRCA1\" is both the string and the code and the code system name is \"HGNC\". OTHER NAME(S): NOTE(S):" ; "Gene Name" , "Gene Symbol" , "Gene.symbol" , "Official Gene Name" , "gene" ; "A unique gene name approved by an organism specific nomenclature committee." ; rdfs:label "Gene Symbol" ; :disnetLabel "Gene Symbol" . ### http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7057 rdf:type owl:Class ; owl:disjointWith , ; "C7057" ; "Conceptual Entity" ; "Disease, Disorder or Finding" ; "Disease, Disorder or Finding" ; "A condition that is relevant to human neoplasms and non-neoplastic disorders. This includes observations, test results, history and other concepts relevant to the characterization of human pathologic conditions." ; rdfs:label "Disease, Disorder or Finding" ; :disnetLabel "Disease" . ### http://purl.bioontology.org/ontology/SNOMEDCT/62014003 rdf:type owl:Class ; "Adverse reaction to drug" ; """All noxious and unintended responses to a medicinal product related to any dose should be considered adverse drug reactions (from US FDA 'Guideline for Industry, Clinical Safety Data Management: Definitions and Standards for Expedited Reporting'). All noxious and unintended responses to a medicinal product related to any dose should be considered adverse drug reactions (from US FDA Guideline for Industry, Clinical Safety Data Management: Definitions and Standards for Expedited Reporting).""" ; ; rdfs:label "Adverse reaction to drug" ; """Drug reaction Adverse reaction caused by drug (disorder) ADR - Adverse drug reaction Adverse reaction to medication Adverse reaction caused by drug Adverse drug effect Adverse drug reaction""" ; :disnetLabel "Drug Phenotype Side Effect" . ### http://purl.obolibrary.org/obo/HP_0000118 rdf:type owl:Class ; ; "A phenotypic abnormality." ; "UMLS:C4021819" ; "Organ abnormality" ; "human_phenotype" ; "HP:0000118" ; rdfs:comment "This is the root of the phenotypic abnormality subontology of the HPO." ; rdfs:label "Phenotypic abnormality" ; "HP:0000118" ; :disnetLabel "Disease class" . [ rdf:type owl:Axiom ; owl:annotatedSource ; owl:annotatedProperty ; owl:annotatedTarget "A phenotypic abnormality." ; "HPO:probinson" ] . ### http://purl.obolibrary.org/obo/PR_000000001 rdf:type owl:Class ; rdfs:label "ProteinClass" ; :disnetLabel "Protein class" . ### http://purl.obolibrary.org/obo/SO_0001060 rdf:type owl:Class ; "A sequence_variant is a non exact copy of a sequence_feature or genome exhibiting one or more sequence_alteration." ; "Jannovar:sequence_variant" , "VAAST:sequence_variant" , "sequence variant" ; "sequence" ; "ANNOVAR:unknown" ; "SO:0001060" ; rdfs:label "sequence_variant" ; :disnetLabel "Variant" . [ rdf:type owl:Axiom ; owl:annotatedSource ; owl:annotatedProperty ; owl:annotatedTarget "A sequence_variant is a non exact copy of a sequence_feature or genome exhibiting one or more sequence_alteration." ; "SO:ke" ] . [ rdf:type owl:Axiom ; owl:annotatedSource ; owl:annotatedProperty ; owl:annotatedTarget "Jannovar:sequence_variant" ; "http://doc-openbio.readthedocs.org/projects/jannovar/en/master/var_effects.html" ; ] . [ rdf:type owl:Axiom ; owl:annotatedSource ; owl:annotatedProperty ; owl:annotatedTarget "VAAST:sequence_variant" ; ] . [ rdf:type owl:Axiom ; owl:annotatedSource ; owl:annotatedProperty ; owl:annotatedTarget "ANNOVAR:unknown" ; "http://www.openbioinformatics.org/annovar/annovar_download.html" ; ] . ### http://rdf.ebi.ac.uk/terms/chembl#DrugIndication rdf:type owl:Class ; rdfs:label "ChEMBL Drug Indication Class" ; "ChEMBL Drug Indication Class" ; :disnetLabel "Drug Phenotype Indication" . ### http://rdf.ebi.ac.uk/terms/chembl#Mechanism rdf:type owl:Class ; rdfs:label "ChEMBL Mechanism Class" ; "ChEMBL Mechanism Class" ; :disnetLabel "Drug Target Association" . ### http://rdf.ebi.ac.uk/terms/chembl#Substance rdf:type owl:Class ; owl:disjointWith , :Phenotype ; rdfs:label "ChEMBL Substance Class" ; "ChEMBL Substance Class" ; :disnetLabel "Drug" . ### http://rdf.ebi.ac.uk/terms/chembl#Target rdf:type owl:Class ; rdfs:label "ChEMBL Target Class" ; "ChEMBL Target Class" ; :disnetLabel "Target" . ### http://semanticscience.org/resource/SIO_000326 rdf:type owl:Class ; "SIO_000326" ; "A concept is term that refers to a generalization of a set of attributes or entities."@en ; rdfs:isDefinedBy ; rdfs:label "concept"@en ; :disnetLabel "Semantic Type" . ### http://semanticscience.org/resource/SIO_000791 rdf:type owl:Class ; "SIO_000791" ; "A sequence start position is the start position for a sequence of characters."@en ; rdfs:isDefinedBy ; rdfs:label "sequence start position"@en ; :disnetLabel "Chromosome position" . ### http://semanticscience.org/resource/SIO_000897 rdf:type owl:Class ; owl:disjointWith , :DiseaseNcrna , :DrugDisease ; "SIO_000897" ; "An assocation is a relationship between two or more entities derived by some informational analysis."@en ; rdfs:isDefinedBy ; rdfs:label "association"@en ; :disnetLabel "Association" . ### http://semanticscience.org/resource/SIO_000899 rdf:type owl:Class ; "SIO_000899" ; "A chromosome is a molecular complex of circular or linear DNA and bound proteins."@en ; rdfs:comment "A chromosome is a molecular complex of circular or linear DNA and bound proteins." ; rdfs:isDefinedBy ; rdfs:label "chromosome"@en ; :disnetLabel "Chromosome" . ### http://semanticscience.org/resource/SIO_000983 rdf:type owl:Class ; rdfs:subClassOf ; owl:disjointWith :DiseaseNcrna , :DrugDisease ; "SIO_000983" ; "A gene-disease association is an association between a gene and a disease."@en ; rdfs:isDefinedBy ; rdfs:label "gene-disease association"@en ; :disnetLabel "Gene Disease Association" . ### http://semanticscience.org/resource/SIO_001006 rdf:type owl:Class ; rdfs:subClassOf ; owl:disjointWith :DrugDisease , :DrugPhenotypeIndication , :DrugPhenotypeSideEffect , :DrugTarget ; "SIO_001006" ; "A drug-drug interaction is an interaction in which two drugs interact in such a way to produce a non-additive biological response."@en ; rdfs:isDefinedBy ; rdfs:label "drug drug interaction"@en ; :disnetLabel "DDI" . ### http://semanticscience.org/resource/SIO_001351 rdf:type owl:Class ; "SIO_001351" ; """DisGeNET Disease specificity is a measure of disease coverage. It is calculated from the negative base 2 log of the ratio of number of diseases associated to the total number of diseases. The measure is described here: http://www.disgenet.org/web/DisGeNET/menu/dbinfo#specificity"""@en ; rdfs:isDefinedBy ; rdfs:label "DisGeNET disease specificity"@en ; :disnetLabel "Disease Specificity" . ### http://semanticscience.org/resource/SIO_001352 rdf:type owl:Class ; "SIO_001352" ; """The DisGeNET pleiotropy index is a measure of specificity as it pertains to classes of disease. The disease pleotropy index is computed from the ratio of the number of disease classes associated with an entity over the total number of disease classes multplied by 100. The measure is defined here: http://www.disgenet.org/web/DisGeNET/menu/dbinfo#pleiotropy"""@en ; rdfs:isDefinedBy ; rdfs:label "DisGeNET Pleiotropy Index"@en ; :disnetLabel "Disease Pleiotropy" . ### http://vocabularies.wikipathways.org/wp#Pathway rdf:type owl:Class ; rdfs:comment "A biological process representing a set of interactions and relationships among genes, proteins, metabolites, and other factors in the context of cellular compartments, tissues and organisms."@en ; rdfs:label "Pathway"@en ; ; :disnetLabel "Pathway" . ### http://www.drugtargetontology.org/dto/DTO_00102000 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_00102000] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_01300327 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_01300327] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_02300001 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_02300001] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_03300101 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_03300101] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_05007378 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_05007378] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_05007405 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_05007405] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_05007527 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_05007527] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_05007530 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_05007530] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_05007542 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_05007542] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_05007557 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_05007557] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_05007575 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_05007575] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_05007584 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_05007584] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_05007599 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_05007599] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_05007608 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_05007608] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_05007612 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_05007612] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_05007613 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_05007613] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_05007616 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_05007616] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_05007620 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_05007620] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_05007621 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_05007621] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_05007624 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_05007624] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.drugtargetontology.org/dto/DTO_05007697 rdf:type owl:Class ; rdfs:subClassOf ; ; rdfs:comment "DTO protein class [dto:DTO_05007697] in which at least one gene in DisGeNET is classified to. Protein classes are identified by the DTO id."@en ; "http://drugtargetontology.org/" . ### http://www.orpha.net/ORDO/Orphanet_409967 rdf:type owl:Class ; "Number of newly diagnosed cases in a population in 1 year."@en ; rdfs:label "annual incidence" ; :disnetLabel "Prevalence class" . ### http://www.orpha.net/ORDO/Orphanet_557492 rdf:type owl:Class ; "A collection of clinical entities sharing a set of common features."@en ; rdfs:label "group of disorders" ; :disnetLabel "Orpha" . ### http://www.orpha.net/ORDO/Orphanet_C009 rdf:type owl:Class ; "Refers to a country, a continent or the whole world."@en ; rdfs:label "geography" ; :disnetLabel "Prevalence" . ### https://w3id.org/eboca/sem-disnet#DiseaseNcrna :DiseaseNcrna rdf:type owl:Class ; rdfs:subClassOf ; owl:disjointWith :DrugDisease ; rdfs:comment "A disease-ncRNA association is an association between a disease and an untranslated RNA (ncRNA)." ; rdfs:label "Disease-ncRNA Association" ; :disnetLabel "Disease ncRNA Association" . ### https://w3id.org/eboca/sem-disnet#DiseasePhenotype :DiseasePhenotype rdf:type owl:Class ; rdfs:subClassOf ; rdfs:comment "A disease-phenotype association is an association between disease and a phenotype, which corresponds to a subjective evidence of disease perceived by the patient." ; rdfs:label "Disease-Phenotype Association" ; :disnetLabel "Disease Phenotype Association" . ### https://w3id.org/eboca/sem-disnet#DiseaseVariant :DiseaseVariant rdf:type owl:Class ; rdfs:subClassOf ; rdfs:comment "Association between a disease and a genetic variant." ; rdfs:label "Disease-Variant Association" ; :disnetLabel "Disease Variant Association" . ### https://w3id.org/eboca/sem-disnet#DrugDisease :DrugDisease rdf:type owl:Class ; rdfs:subClassOf , ; owl:disjointWith :DrugPhenotypeIndication , :DrugPhenotypeSideEffect , :DrugTarget ; "Drug-disease associations refer to the effects that can be induced by the interaction between a drug and a disease." ; rdfs:label "Drug-Disease Association" ; :disnetLabel "Drug Disease Association" . ### https://w3id.org/eboca/sem-disnet#DrugDiseaseInferred :DrugDiseaseInferred rdf:type owl:Class ; rdfs:subClassOf :DrugDisease ; rdfs:comment "Drug Disease Associations not classifed as Therapeutic or Marker which are given an associated inferred score." ; rdfs:label "Drug Disease Inferred" ; :disnetLabel "Drug Disease Inferred" . ### https://w3id.org/eboca/sem-disnet#DrugDiseaseMarker :DrugDiseaseMarker rdf:type owl:Class ; rdfs:subClassOf :DrugDisease ; rdfs:comment "Drug that acts like a marker when associated with a disease. A chemical that correlates with a disease or may play a role in the etiology of a disease." ; rdfs:label "Drug Disease Marker" ; :disnetLabel "Drug Disease Marker" . ### https://w3id.org/eboca/sem-disnet#DrugDiseaseTherapeutic :DrugDiseaseTherapeutic rdf:type owl:Class ; rdfs:subClassOf :DrugDisease ; rdfs:comment "Drug that has a therapeutic effect when associated with a disease. The drug is used to treat the disease in order to reduce or eliminate its symptoms." ; rdfs:label "Drug Disease Therapeutic" ; :disnetLabel "Drug Disease Therapeutic" . ### https://w3id.org/eboca/sem-disnet#DrugPhenotypeIndication :DrugPhenotypeIndication rdf:type owl:Class ; rdfs:subClassOf , ; owl:disjointWith :DrugPhenotypeSideEffect , :DrugTarget ; rdfs:comment "Relationship between the desirable measurable effects that cause changes in a patient's phenotype and the response to treatment with a drug which is indicated to treat them." ; rdfs:label "Drug-Phenotype Indication" ; :disnetLabel "Drug Phenotype Indication" . ### https://w3id.org/eboca/sem-disnet#DrugPhenotypeSideEffect :DrugPhenotypeSideEffect rdf:type owl:Class ; rdfs:subClassOf , ; owl:disjointWith :DrugTarget ; rdfs:comment "Secondary and undesirable measurable effects that cause patient phenotype changes in response to the treatment with a drug." ; rdfs:label "Drug-Phenotype Side Effect" ; :disnetLabel "Drug Phenotype Side Effect" . ### https://w3id.org/eboca/sem-disnet#DrugTarget :DrugTarget rdf:type owl:Class ; rdfs:subClassOf , ; rdfs:comment "Association between a drug and a target in order to achieve disease treatment by different action types or mechanism of action." ; rdfs:label "Drug-Target Association" ; :disnetLabel "Drug Target Association" . ### https://w3id.org/eboca/sem-disnet#Phenotype :Phenotype rdf:type owl:Class ; rdfs:comment "Observable and detectable signs in a patient due to the effects caused by a disease or a drug causing changes in their original appearence." ; rdfs:label "Phenotype" ; :disnetLabel "Phenotype" . ### https://w3id.org/eboca/sem-disnet#Ppi :Ppi rdf:type owl:Class ; rdfs:subClassOf , ; rdfs:comment "Association between two proteins by physical contacts of high specificity that occur in a specific molecular context with a certain confidence value." ; rdfs:label "Protein-Protein Interaction" ; :disnetLabel "PPI" . ### https://w3id.org/eboca/sem-disnet#Prevalence :Prevalence rdf:type owl:Class ; rdfs:subClassOf , ; rdfs:comment "Association between an oprhan disease and the incidence according to the geographical location." ; rdfs:label "Prevalence" ; :disnetLabel "Prevalence" . ### Generated by the OWL API (version 5.1.18) https://github.com/owlcs/owlapi/