diff --git a/README.md b/README.md index afa8cb3596fcaeb829d8ce361374878a6d1eebd3..2837c52fa84b6e2f620b79b146c9caa189efe5ac 100644 --- a/README.md +++ b/README.md @@ -4,24 +4,45 @@ Additional `data.xlsx` descriptionExcel file with different sheets that contain - **DR cases – repoDB** ”Drug repurposing cases extracted from the repoDB database. We excluded those caseswhere the disease and the drug shared the drug target protein. The GDA score wasdepicted too. + + - **DR cases – Literature** -”Drug repurposing cases selected from the Literature1 . We excluded those cases wherethe disease and the drug shared the drug target protein. Moreover, we only consideredthe new disease for which the drug was repositioned and not the original one for whichit was indicated. Cases where the disease and the drug shared the target protein wereexcluded. The GDA score was depicted too. + +Drug repurposing cases selected from the Literature1 . We excluded those cases wherethe disease and the drug shared the drug target protein. Moreover, we only consideredthe new disease for which the drug was repositioned and not the original one for whichit was indicated. Cases where the disease and the drug shared the target protein wereexcluded. The GDA score was depicted too. + + - **PP – repoDB** + Unique protein pairs from the drug repurposing repoDB cases. + + - **PP – Literature** + Unique protein pairs from the drug repurposing literature cases. + + - **PP by class – repoDB** + Protein pairs filtered by PANTHERdb class from the drug repurposing repoDB cases. We made sure the pairs did not share class or classes. + + - **PP by class – Literature** + Protein pairs filtered by PANTHERdb class from the drug repurposong literature cases.We made sure the pairs did not share class or classes. + + - **PP – Distances** + The distance value for each protein pair is included for every embedding method. We indicated if the protein pair belonged to repoDB, Literature or both datasets. + + - **PP by class – Distances** + The distance value for each protein pair filtered by PANTHERdb class is included forevery embedding method. We indicated if the protein pair belongede to repoDB,Literature or both datasets. \ No newline at end of file