diff --git a/Network Medicine/Data/Nodes/pat.tsv b/Network Medicine/Data/Nodes/pat.tsv new file mode 100644 index 0000000000000000000000000000000000000000..700c88c499bcd7d11943a6760eb2f4ed9b7cef4e --- /dev/null +++ b/Network Medicine/Data/Nodes/pat.tsv @@ -0,0 +1,1106 @@ +id name +WP100 Glutathione metabolism +WP106 Alanine and aspartate metabolism +WP107 Translation Factors +WP111 Electron Transport Chain (OXPHOS system in mitochondria) +WP117 GPCRs, Other +WP12 Osteoclast Signaling +WP127 IL-5 Signaling Pathway +WP129 Matrix Metalloproteinases +WP134 Pentose Phosphate Metabolism +WP136 Phase I biotransformations, non P450 +WP138 Androgen receptor signaling pathway +WP1403 AMP-activated Protein Kinase (AMPK) Signaling +WP1422 Sphingolipid pathway +WP1423 Ganglio Sphingolipid Metabolism +WP1424 Globo Sphingolipid Metabolism +WP1425 Bone Morphogenic Protein (BMP) Signalling and Regulation +WP143 Fatty Acid Beta Oxidation +WP1433 Nucleotide-binding Oligomerization Domain (NOD) pathway +WP1434 Osteopontin Signaling +WP1438 Influenza A virus infection +WP1449 Regulation of toll-like receptor signaling pathway +WP1455 Serotonin Transporter Activity +WP1471 Target Of Rapamycin (TOR) Signaling +WP1495 Glycine Metabolism +WP15 Selenium Micronutrient Network +WP1528 Physiological and Pathological Hypertrophy of the Heart +WP1530 miRNA Regulation of DNA Damage Response +WP1531 Vitamin D Metabolism +WP1533 Vitamin B12 Metabolism +WP1539 Angiogenesis +WP1541 Energy Metabolism +WP1544 MicroRNAs in cardiomyocyte hypertrophy +WP1545 miRNAs involved in DNA damage response +WP1559 TFs Regulate miRNAs related to cardiac hypertrophy +WP1584 Type II diabetes mellitus +WP1589 Folate-Alcohol and Cancer Pathway Hypotheses +WP1591 Heart Development +WP1600 Nicotine Metabolism +WP1601 Fluoropyrimidine Activity +WP1602 Nicotine Activity on Dopaminergic Neurons +WP1603 Nicotine Activity on Chromaffin Cells +WP1604 Codeine and Morphine Metabolism +WP167 Eicosanoid Synthesis +WP170 Nuclear Receptors +WP1742 TP53 Network +WP176 Folate Metabolism +WP1772 Apoptosis Modulation and Signaling +WP1775 Cell Cycle Checkpoints +WP1780 ABC-family proteins mediated transport +WP1781 Advanced glycosylation endproduct receptor signaling +WP1784 Apoptotic execution phase +WP1785 Asparagine N-linked glycosylation +WP1788 Bile acid and bile salt metabolism +WP1789 Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA +WP179 Cell Cycle +WP1793 Cell junction organization +WP1794 Cell surface interactions at the vascular wall +WP1795 Cholesterol biosynthesis +WP1797 Circadian Clock +WP1798 Complement cascade +WP1799 Costimulation by the CD28 family +WP1800 Presynaptic depolarization and calcium channel opening +WP1802 Dissolution of Fibrin Clot +WP1803 DNA Damage Bypass +WP1804 DNA Damage Reversal +WP1809 Effects of PIP2 hydrolysis +WP1811 Eukaryotic Translation Elongation +WP1812 Eukaryotic Translation Initiation +WP1813 Eukaryotic Translation Termination +WP1815 Factors involved in megakaryocyte development and platelet production +WP1818 Formation of Fibrin Clot (Clotting Cascade) +WP1820 Gap junction trafficking and regulation +WP1822 Generic Transcription Pathway +WP1823 GP1b-IX-V activation signalling +WP1826 GPVI-mediated activation cascade +WP1829 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell +WP183 Proteasome Degradation +WP1831 Integration of energy metabolism +WP1833 Integrin cell surface interactions +WP1835 Interferon alpha/beta signaling +WP1836 Interferon gamma signaling +WP1838 Interleukin-1 processing +WP1839 Interleukin-1 family signaling +WP1840 Interleukin-3, Interleukin-5 and GM-CSF signaling +WP1841 Intrinsic Pathway for Apoptosis +WP1842 Kinesins +WP1843 L1CAM interactions +WP1845 MAPK targets/ Nuclear events mediated by MAP kinases +WP185 Integrin-mediated Cell Adhesion +WP1850 Metabolism of nitric oxide +WP1852 Metabolism of porphyrins +WP1857 Metabolism of water-soluble vitamins and cofactors +WP1858 Mitotic G1-G1/S phases +WP1859 Mitotic G2-G2/M phases +WP186 Homologous recombination +WP1861 mRNA Capping +WP1862 mRNA Editing +WP1865 Myogenesis +WP1866 NCAM signaling for neurite out-growth +WP1867 Nephrin family interactions +WP1868 Netrin-1 signaling +WP1870 Neurotransmitter clearance +WP1871 Neurotransmitter release cycle +WP1872 Neurotransmitter uptake and metabolism In glial cells +WP1873 Signaling by NTRK1 (TRKA) +WP1874 Nucleosome assembly +WP1877 Passive transport by Aquaporins +WP1878 Peroxisomal lipid metabolism +WP1883 Platelet Adhesion to exposed collagen +WP1884 Platelet Aggregation (Plug Formation) +WP1885 Platelet homeostasis +WP1887 Post-translational modification: synthesis of GPI-anchored proteins +WP1889 Processing of Capped Intron-Containing Pre-mRNA +WP1890 Processing of Capped Intronless Pre-mRNA +WP1892 Protein folding +WP1895 Rap1 signalling +WP1896 Regulation of Apoptosis +WP1898 Regulation of DNA replication +WP1902 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. +WP1903 Response to elevated platelet cytosolic Ca2+ +WP1904 DDX58/IFIH1-mediated induction of interferon-alpha/beta +WP1906 RNA Polymerase II Transcription +WP1907 Semaphorin interactions +WP1908 Signal amplification +WP1909 Signal regulatory protein family interactions +WP1910 Signaling by EGFR +WP1913 Signaling by Insulin receptor +WP1916 Signaling by PDGF +WP1917 Signaling by Rho GTPases +WP1918 Signaling by ROBO receptors +WP1919 Signaling by VEGF +WP1925 Synthesis of DNA +WP1926 Transport of glycerol from adipocytes to the liver by Aquaporins +WP1927 TCR signaling +WP1928 Telomere Maintenance +WP1929 Thrombin signalling through proteinase activated receptors (PARs) +WP1934 Transmission across Electrical Synapses +WP1935 Transport of bile salts and organic acids, metal ions and amine compounds +WP1936 Transport of inorganic cations/anions and amino acids/oligopeptides +WP1937 Transport of vitamins, nucleosides, and related molecules +WP1938 tRNA Aminoacylation +WP1939 Unfolded Protein Response (UPR) +WP1941 Peroxisomal beta-oxidation of tetracosanoyl-CoA +WP1946 Cori Cycle +WP195 IL-1 signaling pathway +WP197 Cholesterol Biosynthesis Pathway +WP1971 Integrated Cancer Pathway +WP1978 Opioid Signalling +WP1980 Nucleotide Excision Repair +WP1981 Thyroxine (Thyroid Hormone) Production +WP1982 Sterol Regulatory Element-Binding Proteins (SREBP) signalling +WP1984 Integrated Breast Cancer Pathway +WP1991 SRF and miRs in Smooth Muscle Differentiation and Proliferation +WP1992 Genes targeted by miRNAs in adipocytes +WP1995 Effects of Nitric Oxide +WP2007 Iron metabolism in placenta +WP2011 SREBF and miR33 in cholesterol and lipid homeostasis +WP2018 RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway +WP2023 Cell Differentiation - Index expanded +WP2029 Cell Differentiation - Index +WP2032 Human Thyroid Stimulating Hormone (TSH) signaling pathway +WP2034 Leptin signaling pathway +WP2035 Follicle Stimulating Hormone (FSH) signaling pathway +WP2036 TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway +WP2037 Prolactin Signaling Pathway +WP2038 Regulation of Microtubule Cytoskeleton +WP205 IL-7 Signaling Pathway +WP2059 Alzheimers Disease +WP206 Fatty Acid Omega Oxidation +WP2064 Neural Crest Differentiation +WP2112 IL17 signaling pathway +WP2113 Type III interferon signaling +WP2118 Arrhythmogenic Right Ventricular Cardiomyopathy +WP2197 Endothelin Pathways +WP22 IL-9 Signaling Pathway +WP2203 Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway +WP2249 Metastatic brain tumor +WP2261 Signaling Pathways in Glioblastoma +WP2267 Synaptic Vesicle Pathway +WP2272 Pathogenic Escherichia coli infection +WP2276 Glial Cell Differentiation +WP2289 Drug Induction of Bile Acid Pathway +WP229 Irinotecan Pathway +WP2290 RalA downstream regulated genes +WP2291 Deregulation of Rab and Rab Effector Genes in Bladder Cancer +WP23 B Cell Receptor Signaling Pathway +WP231 TNF alpha Signaling Pathway +WP2324 AGE/RAGE pathway +WP2328 Allograft Rejection +WP2332 Interleukin-11 Signaling Pathway +WP2333 Trans-sulfuration pathway +WP2338 miRNA Biogenesis +WP2355 Corticotropin-releasing hormone signaling pathway +WP2359 Parkin-Ubiquitin Proteasomal System pathway +WP236 Adipogenesis +WP2361 Gastric Cancer Network 1 +WP2363 Gastric Cancer Network 2 +WP2366 Butyrate-induced histone acetylation +WP2369 Histone Modifications +WP237 Glucocorticoid and Mineralcorticoid Metabolism +WP2371 Parkinsons Disease Pathway +WP2374 Oncostatin M Signaling Pathway +WP2380 Brain-Derived Neurotrophic Factor (BDNF) signaling pathway +WP24 Peptide GPCRs +WP2406 Cardiac Progenitor Differentiation +WP241 One Carbon Metabolism +WP2431 Spinal Cord Injury +WP2436 Dopamine metabolism +WP244 Alpha 6 Beta 4 signaling pathway +WP2446 Retinoblastoma Gene in Cancer +WP2447 Amyotrophic lateral sclerosis (ALS) +WP2453 TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc) +WP2456 HIF1A and PPARG regulation of glycolysis +WP247 Small Ligand GPCRs +WP2485 NAD Biosynthesis II (from tryptophan) +WP2491 Diclofenac Metabolic Pathway +WP2507 Nanomaterial induced apoptosis +WP2509 Nanoparticle triggered autophagic cell death +WP2513 Nanoparticle triggered regulated necrosis +WP2516 ATM Signaling Pathway +WP2525 Trans-sulfuration and one carbon metabolism +WP2526 PDGF Pathway +WP2533 Glycerophospholipid Biosynthetic Pathway +WP2536 Colchicine Metabolic Pathway +WP254 Apoptosis +WP2542 Sulindac Metabolic Pathway +WP2572 Primary Focal Segmental Glomerulosclerosis FSGS +WP2583 T-Cell Receptor and Co-stimulatory Signaling +WP2586 Aryl Hydrocarbon Receptor Netpath +WP2596 Gastric acid production +WP2597 Secretion of Hydrochloric Acid in Parietal Cells +WP26 Signal Transduction of S1P Receptor +WP262 EBV LMP1 signaling +WP2636 Common Pathways Underlying Drug Addiction +WP2637 Structural Pathway of Interleukin 1 (IL-1) +WP2640 Aripiprazole Metabolic Pathway +WP2643 Nanoparticle-mediated activation of receptor signaling +WP2645 Heroin metabolism +WP2646 Lidocaine metabolism +WP2650 Arachidonic acid metabolism +WP2652 Mitotic Prometaphase +WP2653 PIP3 activates AKT signaling +WP2654 Mitotic Prophase +WP2655 ATF6 (ATF6-alpha) activates chaperone genes +WP2656 TAK1 activates NFkB by phosphorylation and activation of IKKs complex +WP2657 Growth hormone receptor signaling +WP2658 HIV Life Cycle +WP2659 Deadenylation-dependent mRNA decay +WP2662 Vasopressin regulates renal water homeostasis via Aquaporins +WP2664 Gastrin-CREB signalling pathway via PKC and MAPK +WP2665 Neurotoxicity of clostridium toxins +WP2666 Elastic fibre formation +WP2669 Potassium Channels +WP2670 Iron uptake and transport +WP2671 Defensins +WP2672 ISG15 antiviral mechanism +WP2673 Interleukin-7 signaling +WP2675 Signaling by NODAL +WP2677 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) +WP2678 Prolactin receptor signaling +WP2679 MHC class II antigen presentation +WP268 Notch Signaling +WP2681 Erythrocytes take up oxygen and release carbon dioxide +WP2683 Influenza Life Cycle +WP2684 Host Interactions of HIV factors +WP2685 GABA synthesis, release, reuptake and degradation +WP2686 Regulation of cholesterol biosynthesis by SREBP (SREBF) +WP2688 DAG and IP3 signaling +WP2690 Cytosolic iron-sulfur cluster assembly +WP2691 Peptide hormone biosynthesis +WP2694 DAP12 interactions +WP2697 Fertilization +WP2698 Meiotic recombination +WP2700 Latent infection of Homo sapiens with Mycobacterium tuberculosis +WP2702 Mitochondrial iron-sulfur cluster biogenesis +WP2703 Extracellular matrix organization +WP2706 Activation of gene expression by SREBF (SREBP) +WP2708 Collagen degradation +WP2709 Trafficking and processing of endosomal TLR +WP2710 Nonsense-Mediated Decay (NMD) +WP2712 Abacavir transport and metabolism +WP2713 Signaling by SCF-KIT +WP2714 Signaling by Hippo +WP2715 Metabolism of non-coding RNA +WP2717 Mitochondrial protein import +WP2718 Signaling by NOTCH2 +WP2719 Fcgamma receptor (FCGR) dependent phagocytosis +WP272 Blood Clotting Cascade +WP2720 Signaling by NOTCH1 +WP2721 Signaling by NOTCH4 +WP2722 Signaling by NOTCH3 +WP2724 alpha-linolenic (omega3) and linoleic (omega6) acid metabolism +WP2725 Collagen biosynthesis and modifying enzymes +WP2727 Regulation of Hypoxia-inducible Factor (HIF) by oxygen +WP2728 Incretin synthesis, secretion, and inactivation +WP2729 Metabolism of Angiotensinogen to Angiotensins +WP2731 Meiotic synapsis +WP2732 Interleukin-2 family signaling +WP2733 Regulation of mRNA stability by proteins that bind AU-rich elements +WP2734 Ubiquinol biosynthesis +WP2735 RAF/MAP kinase cascade +WP2736 Insulin processing +WP2737 SRP-dependent cotranslational protein targeting to membrane +WP2738 YAP1- and WWTR1 (TAZ)-stimulated gene expression +WP2740 Glycerophospholipid biosynthesis +WP2741 Inositol phosphate metabolism +WP2742 Signaling by TGF-beta Receptor Complex +WP2743 Glycosaminoglycan metabolism +WP2744 Erythrocytes take up carbon dioxide and release oxygen +WP2746 Signaling by the B Cell Receptor (BCR) +WP2747 PI Metabolism +WP2748 Energy dependent regulation of mTOR by LKB1-AMPK +WP2749 Metabolism of steroid hormones +WP2751 Transcriptional regulation of white adipocyte differentiation +WP2752 MyD88-independent TLR4 cascade +WP2753 ATF4 activates genes +WP2754 Neurotransmitter receptors and postsynaptic signal transmission +WP2755 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer +WP2757 Mitotic Metaphase and Anaphase +WP2759 Fc epsilon receptor (FCERI) signaling +WP2760 Signaling by BMP +WP2761 MyD88:MAL(TIRAP) cascade initiated on plasma membrane +WP2762 Gamma carboxylation, hypusine formation and arylsulfatase activation +WP2763 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways +WP2765 Mitotic Telophase/Cytokinesis +WP2766 The citric acid (TCA) cycle and respiratory electron transport +WP2768 MyD88 dependent cascade initiated on endosome +WP2769 Activation of Matrix Metalloproteinases +WP2770 Reversible hydration of carbon dioxide +WP2771 Host Interactions with Influenza Factors +WP2772 S Phase +WP2773 Degradation of beta-catenin by the destruction complex +WP2774 Degradation of the extracellular matrix +WP2775 Toll-like Receptor Cascades +WP2776 Visual phototransduction +WP2777 Translocation of SLC2A4 (GLUT4) to the plasma membrane +WP2778 SUMOylation +WP2780 Signaling by ERBB2 +WP2781 Signaling by ERBB4 +WP2784 Binding and Uptake of Ligands by Scavenger Receptors +WP2785 M/G1 Transition +WP2786 Pre-NOTCH Expression and Processing +WP2787 Syndecan interactions +WP2788 Sphingolipid metabolism +WP2790 WNT ligand biogenesis and trafficking +WP2791 Signaling by Activin +WP2792 MAP kinase activation +WP2794 Cytosolic sensors of pathogen-associated DNA +WP2795 Cardiac Hypertrophic Response +WP2797 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) +WP2798 Assembly of collagen fibrils and other multimeric structures +WP2799 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) +WP2801 MyD88 cascade initiated on plasma membrane +WP2805 exRNA mechanism of action and biogenesis +WP2806 Human Complement System +WP2813 Mammary gland development pathway - Embryonic development (Stage 1 of 4) +WP2814 Mammary gland development pathway - Puberty (Stage 2 of 4) +WP2815 Mammary gland development pathway - Involution (Stage 4 of 4) +WP2816 Felbamate Metabolism +WP2817 Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4) +WP2821 Transcriptional regulation of pluripotent stem cells +WP2824 Detoxification of Reactive Oxygen Species +WP2826 Cocaine metabolism +WP2828 Bladder Cancer +WP2840 Hair Follicle Development: Cytodifferentiation (Part 3 of 3) +WP2846 Proprotein convertase subtilisin/kexin type 9 (PCSK9) mediated LDL receptor degradation +WP2848 Differentiation Pathway +WP2849 Hematopoietic Stem Cell Differentiation +WP2853 Endoderm Differentiation +WP2854 Gene regulatory network modelling somitogenesis +WP2855 Dopaminergic Neurogenesis +WP2857 Mesodermal Commitment Pathway +WP2858 Ectoderm Differentiation +WP286 IL-3 Signaling Pathway +WP2864 Apoptosis-related network due to altered Notch3 in ovarian cancer +WP2865 IL1 and megakaryocytes in obesity +WP2868 TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer +WP2870 Extracellular vesicle-mediated signaling in recipient cells +WP2873 Aryl Hydrocarbon Receptor Pathway +WP2874 Liver X Receptor Pathway +WP2875 Constitutive Androstane Receptor Pathway +WP2876 Pregnane X Receptor pathway +WP2877 Vitamin D Receptor Pathway +WP2878 PPAR Alpha Pathway +WP2879 Farnesoid X Receptor Pathway +WP288 NLR Proteins +WP2881 Estrogen Receptor Pathway +WP2882 Nuclear Receptors Meta-Pathway +WP2884 NRF2 pathway +WP2889 Oxytocin signaling +WP289 Myometrial Relaxation and Contraction Pathways +WP2895 Differentiation of white and brown adipocyte +WP2911 miRNA targets in ECM and membrane receptors +WP2916 Interactome of polycomb repressive complex 2 (PRC2) +WP2942 DDX1 as a regulatory component of the Drosha microprocessor +WP2943 Hypoxia-mediated EMT and Stemness +WP299 Nuclear Receptors in Lipid Metabolism and Toxicity +WP3 Phytochemical activity on NRF2 transcriptional activation +WP304 Kit receptor signaling pathway +WP306 Focal Adhesion +WP311 Synthesis and Degradation of Ketone Bodies +WP313 Signaling of Hepatocyte Growth Factor Receptor +WP314 Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation +WP322 Osteoblast Signaling +WP325 Triacylglyceride Synthesis +WP3286 Copper homeostasis +WP3287 Overview of nanoparticle effects +WP3297 EV release from cardiac cells and their functional effects +WP3298 Melatonin metabolism and effects +WP3299 let-7 inhibition of ES cell reprogramming +WP3300 Dual hijack model of Vif in HIV infection +WP3301 MFAP5-mediated ovarian cancer cell motility and invasiveness +WP3302 eIF5A regulation in response to inhibition of the nuclear export system +WP3303 RAC1/PAK1/p38/MMP2 Pathway +WP3305 NoRC negatively regulates rRNA expression +WP3306 Aflatoxin activation and detoxification +WP3307 MAPK6/MAPK4 signaling +WP3308 Oncogene Induced Senescence +WP3309 EPH-Ephrin signaling +WP3310 Mitochondrial translation +WP3312 PRC2 methylates histones and DNA +WP3313 Hedgehog 'on' state +WP3315 O-linked glycosylation +WP3316 Hedgehog 'off' state +WP3317 Caspase activation via Dependence Receptors in the absence of ligand +WP3318 mTOR signalling +WP3320 Miscellaneous transport and binding events +WP3322 RHO GTPases regulate CFTR trafficking +WP3327 SUMOylation of DNA damage response and repair proteins +WP3330 RHO GTPases activate IQGAPs +WP3331 Mitochondrial biogenesis +WP3332 RAF-independent MAPK1/3 activation +WP3333 POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation +WP3334 Signaling by FGFR4 +WP3335 Signaling by FGFR1 +WP3336 Signaling by FGFR3 +WP3337 RHO GTPases activate KTN1 +WP3338 Signaling by FGFR2 +WP3339 TCF dependent signaling in response to WNT +WP334 GPCRs, Class B Secretin-like +WP3345 Resolution of Abasic Sites (AP sites) +WP3348 Macroautophagy +WP3349 TP53 Regulates Metabolic Genes +WP3350 TNFs bind their physiological receptors +WP3351 RHO GTPases activate PAKs +WP3352 Toll Like Receptor 3 (TLR3) Cascade +WP3354 C-type lectin receptors (CLRs) +WP3355 BMAL1:CLOCK,NPAS2 activates circadian gene expression +WP3357 RHO GTPases activate PKNs +WP3358 Caspase activation via Death Receptors in the presence of ligand +WP3359 DNA methylation +WP3360 Uptake and function of diphtheria toxin +WP3363 Sialic acid metabolism +WP3364 SIRT1 negatively regulates rRNA expression +WP3365 RHO GTPases Activate ROCKs +WP3370 RORA activates gene expression +WP3372 TET1,2,3 and TDG demethylate DNA +WP3374 Signaling by Leptin +WP3376 RHO GTPases activate CIT +WP3377 Melanin biosynthesis +WP3379 RHO GTPases Activate Formins +WP3380 TNF signaling +WP3381 Mismatch Repair +WP3382 POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation +WP3383 Regulated Necrosis +WP3384 RHO GTPases Activate Rhotekin and Rhophilins +WP3388 RHO GTPases Activate WASPs and WAVEs +WP3390 Uptake and function of anthrax toxins +WP3391 Senescence-Associated Secretory Phenotype (SASP) +WP3392 LGI-ADAM interactions +WP3394 NR1D1 (REV-ERBA) represses gene expression +WP3395 Cellular response to heat stress +WP3396 RHO GTPases Activate NADPH Oxidases +WP3397 Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 +WP3398 TNFR2 non-canonical NF-kB pathway +WP3399 Base-Excision Repair, AP Site Formation +WP34 Ovarian Infertility Genes +WP3400 TRAIL signaling +WP3401 Hedgehog ligand biogenesis +WP3404 Oxidative Stress Induced Senescence +WP3407 FTO Obesity Variant Mechanism +WP3408 Evolocumab Mechanism +WP3413 NOTCH1 regulation of human endothelial cell calcification +WP3414 Initiation of transcription and translation elongation at the HIV-1 LTR +WP3436 Synthesis, secretion, and deacylation of Ghrelin +WP3472 XBP1(S) activates chaperone genes +WP3486 Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate +WP3498 Assembly of the primary cilium +WP35 G Protein Signaling Pathways +WP3513 Regulation of beta-cell development +WP3527 Preimplantation Embryo +WP3529 Zinc homeostasis +WP3543 DNA Double Strand Break Response +WP3545 NIK-->noncanonical NF-kB signaling +WP3547 Amyloid fiber formation +WP3548 Amine-derived hormones +WP3549 Mitophagy +WP3550 Nonhomologous End-Joining (NHEJ) +WP3551 ROS, RNS production in phagocytes +WP3552 tRNA processing in the nucleus +WP3553 Synthesis of wybutosine at G37 of tRNA(Phe) +WP3555 Metabolism of polyamines +WP3556 Branched-chain amino acid catabolism +WP3558 Beta-catenin independent WNT signaling +WP3560 Cargo concentration in the ER +WP3561 tRNA modification in the nucleus and cytosol +WP3562 Glyoxylate metabolism and glycine degradation +WP3564 Amino acid synthesis and interconversion (transamination) +WP3565 DNA Damage/Telomere Stress Induced Senescence +WP3567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) +WP3568 FasL/ CD95L signaling +WP3569 Fanconi Anemia Pathway +WP357 Fatty Acid Biosynthesis +WP3570 HDR through MMEJ (alt-NHEJ) +WP3571 Gene Silencing by RNA +WP3573 Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism +WP3574 Sulfur amino acid metabolism +WP3575 Endosomal Sorting Complex Required For Transport (ESCRT) +WP3577 Class I MHC mediated antigen processing & presentation +WP3578 trans-Golgi Network Vesicle Budding +WP3579 Surfactant metabolism +WP3580 Methionine De Novo and Salvage Pathway +WP3584 MECP2 and Associated Rett Syndrome +WP3585 Cytosine methylation +WP3591 Sleep regulation +WP3593 MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma +WP3594 Circadian rhythm related genes +WP3595 mir-124 predicted interactions with cell cycle and differentiation +WP3596 miR-517 relationship with ARCN1 and USP1 +WP3599 Transcription factor regulation in adipogenesis +WP3601 Composition of Lipid Particles +WP3602 Human metabolism overview +WP3604 Biochemical Pathways Part I +WP3611 Photodynamic therapy-induced AP-1 survival signaling. +WP3612 Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling +WP3613 Photodynamic therapy-induced unfolded protein response +WP3614 Photodynamic therapy-induced HIF-1 survival signaling +WP3617 Photodynamic therapy-induced NF-kB survival signaling +WP3624 Lung fibrosis +WP3627 Gut-Liver Indole Metabolism +WP363 Wnt Signaling Pathway (Netpath) +WP3630 NAD metabolism, sirtuins and aging +WP3633 Caffeine and Theobromine metabolism +WP3634 Insulin signalling in human adipocytes (normal condition) +WP3635 Insulin signalling in human adipocytes (diabetic condition) +WP364 IL-6 signaling pathway +WP3640 Imatinib and Chronic Myeloid Leukemia +WP3644 NAD+ metabolism +WP3645 NAD+ biosynthetic pathways +WP3646 Hepatitis C and Hepatocellular Carcinoma +WP3651 Pathways Affected in Adenoid Cystic Carcinoma +WP3655 Hypothetical Craniofacial Development Pathway +WP3656 Interleukin-1 Induced Activation of NF-kappa-B +WP3657 Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex +WP3658 Wnt/beta-catenin Signaling Pathway in Leukemia +WP366 TGF-beta Signaling Pathway +WP3664 Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds +WP3666 Metabolism of Dichloroethylene by CYP450 +WP3668 Hypothesized Pathways in Pathogenesis of Cardiovascular Disease +WP3670 Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway +WP3672 LncRNA-mediated mechanisms of therapeutic resistance +WP3674 Tgif disruption of Shh signaling +WP3676 BDNF-TrkB Signaling +WP3678 Amplification and Expansion of Oncogenic Pathways as Metastatic Traits +WP3679 Cell-type Dependent Selectivity of CCK2R Signaling +WP368 Mitochondrial LC-Fatty Acid Beta-Oxidation +WP3680 Association Between Physico-Chemical Features and Toxicity Associated Pathways +WP3684 tRNA modification in the mitochondrion +WP3685 Vitamin D (calciferol) metabolism +WP3790 Wax biosynthesis +WP3791 Selenoamino acid metabolism +WP3793 Lysosomal oligosaccharide catabolism +WP3794 SUMOylation of RNA binding proteins +WP3795 Striated Muscle Contraction +WP3797 Major pathway of rRNA processing in the nucleolus and cytosol +WP3798 Regulation of TP53 Activity through Association with Co-factors +WP3799 SUMOylation of chromatin organization proteins +WP3800 Protein repair +WP3801 ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression +WP3802 TP53 Regulates Transcription of Cell Death Genes +WP3803 Threonine catabolism +WP3804 TP53 Regulates Transcription of Cell Cycle Genes +WP3805 SUMOylation of DNA replication proteins +WP3806 Metabolism of folate and pterines +WP3807 Regulation of TP53 Expression and Degradation +WP3808 TP53 Regulates Transcription of DNA Repair Genes +WP3809 tRNA processing in the mitochondrion +WP3810 Cardiac conduction +WP3811 Smooth Muscle Contraction +WP3812 SALM protein interactions at the synapse +WP3813 Activation of anterior HOX genes in hindbrain development during early embryogenesis +WP3814 Metallothioneins bind metals +WP3816 Regulation of TP53 Activity through Acetylation +WP3817 Interleukin-20 family signaling +WP3818 Signaling by MST1 +WP3819 B-WICH complex positively regulates rRNA expression +WP382 MAPK Signaling Pathway +WP3820 Interleukin-17 signaling +WP3822 Metabolism of vitamin K +WP3823 Regulation of TP53 Activity through Methylation +WP3824 SUMOylation of transcription factors +WP3827 RNA polymerase II transcribes snRNA genes +WP3828 rRNA modification in the nucleus and cytosol +WP3829 rRNA processing +WP383 Striated Muscle Contraction Pathway +WP3838 Regulation of TP53 Activity through Phosphorylation +WP3839 Retinoid metabolism and transport +WP384 Apoptosis Modulation by HSP70 +WP3842 Intra-Golgi and retrograde Golgi-to-ER traffic +WP3844 PI3K-AKT-mTOR signaling pathway and therapeutic opportunities +WP3845 Canonical and Non-canonical Notch signaling +WP3849 MAPK and NFkB Signalling Pathways Inhibited by Yersinia YopJ +WP3850 Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling +WP3851 TLR4 Signaling and Tolerance +WP3853 ERK Pathway in Huntington's Disease +WP3858 Toll-like Receptor Signaling related to MyD88 +WP3859 TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition +WP3863 T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection +WP3865 Novel intracellular components of RIG-I-like receptor (RLR) pathway +WP3869 Cannabinoid receptor signaling +WP3871 Valproic acid pathway +WP3872 Regulation of Apoptosis by Parathyroid Hormone-related Protein +WP3874 Canonical and Non-Canonical TGF-B signaling +WP3875 ATR Signaling +WP3876 BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation +WP3877 Simplified Depiction of MYD88 Distinct Input-Output Pathway +WP3878 ATM Signaling Network in Development and Disease +WP3879 4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression +WP3888 VEGFA-VEGFR2 Signaling Pathway +WP3890 Nanomaterial-induced Inflammasome Activation +WP3891 Benzene metabolism +WP3892 Development of pulmonary dendritic cells and macrophage subsets +WP3893 Development and heterogeneity of the ILC family +WP391 Mitochondrial Gene Expression +WP3915 Angiopoietin Like Protein 8 Regulatory Pathway +WP3924 Hfe effect on hepcidin production +WP3925 Amino Acid metabolism +WP3926 ApoE and miR-146 in inflammation and atherosclerosis +WP3927 BMP Signaling Pathway in Eyelid Development +WP3929 Chemokine signaling pathway +WP3930 EDA Signalling in Hair Follicle Development +WP3931 ESC Pluripotency Pathways +WP3932 Focal Adhesion-PI3K-Akt-mTOR-signaling pathway +WP3933 Kennedy pathway from Sphingolipids +WP3934 Leptin and adiponectin +WP3935 Leptin Insulin Overlap +WP3937 Microglia Pathogen Phagocytosis Pathway +WP3938 miR-222 in Exercise-Induced Cardiac Growth +WP3940 One carbon metabolism and related pathways +WP3941 Oxidative Damage +WP3942 PPAR signaling pathway +WP3943 Robo4 and VEGF Signaling Pathways Crosstalk +WP3944 Serotonin and anxiety-related events +WP3945 TYROBP Causal Network +WP3947 Serotonin and anxiety +WP395 IL-4 Signaling Pathway +WP3958 GPR40 Pathway +WP3959 DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM +WP3963 Mevalonate pathway +WP3965 Lipid Metabolism Pathway +WP3967 miR-509-3p alteration of YAP1/ECM axis +WP3969 H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity +WP3971 Role of Osx and miRNAs in tooth development +WP3972 PDGFR-beta pathway +WP3981 miRNA regulation of prostate cancer signaling pathways +WP3982 miRNA regulation of p53 pathway in prostate cancer +WP399 Wnt Signaling Pathway and Pluripotency +WP3995 Prion disease pathway +WP3996 Ethanol effects on histone modifications +WP3998 Prader-Willi and Angelman Syndrome +WP400 p38 MAPK Signaling Pathway +WP4008 NO/cGMP/PKG mediated Neuroprotection +WP4016 DNA IR-damage and cellular response via ATR +WP4018 Pathways in clear cell renal cell carcinoma +WP4022 Pyrimidine metabolism +WP4030 SCFA and skeletal muscle substrate metabolism +WP4034 Mitochondrial Fatty Acid Beta-Oxidation +WP4035 Intestinal absorption +WP4036 MTF1 activates gene expression +WP4037 Pyrophosphate hydrolysis +WP4038 Transcription from mitochondrial promoters +WP4039 Fructose metabolism +WP404 Nucleotide Metabolism +WP4041 Other interleukin signaling +WP4042 Nucleobase catabolism +WP4043 Cellular hexose transport +WP4046 Receptor-type tyrosine-protein phosphatases +WP4047 PTEN Regulation +WP4048 NADPH regeneration +WP4049 Neutrophil degranulation +WP405 Eukaryotic Transcription Initiation +WP4050 Pentose phosphate pathway +WP4051 Lipid particle organization +WP4052 Interleukin-12 family signaling +WP4053 TBC/RABGAPs +WP4054 Synaptic adhesion-like molecules +WP4055 E3 ubiquitin ligases ubiquitinate target proteins +WP4058 HSP90 chaperone cycle for steroid hormone receptors (SHR) +WP4059 Interconversion of nucleotide di- and triphosphates +WP4061 Import of palmitoyl-CoA into the mitochondrial matrix +WP4063 Interleukin-10 signaling +WP4064 Intracellular oxygen transport +WP4065 Clathrin-mediated endocytosis +WP4066 Interleukin-4 and Interleukin-13 signaling +WP4068 Formation of xylulose-5-phosphate +WP4069 Regulation of TLR by endogenous ligand +WP4070 RAB GEFs exchange GTP for GDP on RABs +WP4071 RAB geranylgeranylation +WP4072 Glycogen metabolism +WP4073 Protein methylation +WP4074 RNA Polymerase I Transcription +WP4075 Carboxyterminal post-translational modifications of tubulin +WP4079 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) +WP408 Oxidative Stress +WP4080 Cargo recognition for clathrin-mediated endocytosis +WP4082 Nucleotide salvage +WP4083 Reelin signalling pathway +WP4084 Nucleobase biosynthesis +WP4085 Phase I - Functionalization of compounds +WP4086 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors +WP4087 Keratinization +WP4088 Mitochondrial calcium ion transport +WP4089 Plasmalogen biosynthesis +WP4090 Choline catabolism +WP4091 Butyrophilin (BTN) family interactions +WP4093 Glucose metabolism +WP4094 Collagen chain trimerization +WP4095 RET signaling +WP4096 Chromatin organization +WP4097 Nicotinate metabolism +WP4098 Ion channel transport +WP4099 rRNA modification in the mitochondrion +WP410 Exercise-induced Circadian Regulation +WP4100 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation +WP4101 Antimicrobial peptides +WP4102 Deubiquitination +WP4103 Intestinal infectious diseases +WP4104 Digestion +WP4105 Transcriptional regulation by RUNX1 +WP4106 Cristae formation +WP4107 Transcriptional regulation by RUNX3 +WP4108 Aryl hydrocarbon receptor signalling +WP4109 Regulation of mitotic cell cycle +WP411 mRNA Processing +WP4110 Post-translational protein phosphorylation +WP4111 Phase II - Conjugation of compounds +WP4112 Vitamin E +WP4113 Ketone body metabolism +WP4114 Fatty acyl-CoA biosynthesis +WP4115 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models +WP4116 Lactose synthesis +WP4117 Regulation of RUNX1 Expression and Activity +WP4119 Listeria monocytogenes entry into host cells +WP4120 Signaling by MET +WP4121 Neddylation +WP4122 Interleukin-6 family signaling +WP4124 Cilium Assembly +WP4125 Protein ubiquitination +WP4126 Galactose catabolism +WP4129 Plasma lipoprotein assembly, remodeling, and clearance +WP4131 Triglyceride metabolism +WP4132 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function +WP4133 Neurexins and neuroligins +WP4134 Processing of SMDT1 +WP4135 RNA Polymerase III Transcription +WP4136 Fibrin Complement Receptor 3 Signaling Pathway +WP4141 PI3K/AKT/mTOR - VitD3 Signalling +WP4142 Metabolism of Spingolipids in ER and Golgi apparatus +WP4146 Macrophage markers +WP4147 PTF1A related regulatory pathway +WP4148 Splicing factor NOVA regulated synaptic proteins +WP4149 White fat cell differentiation +WP4150 Wnt Signaling in Kidney Disease +WP4153 Degradation pathway of sphingolipids, including diseases +WP4155 Endometrial cancer +WP4156 Biosynthesis and regeneration of tetrahydrobiopterin (BH4) and catabolism of phenylalanine, including diseases +WP4157 GHB metabolic pathway +WP4159 GABA receptor Signaling +WP4172 PI3K-Akt Signaling Pathway +WP4174 Metabolism of Tetrahydrocannabinol (THC) +WP4186 Somatroph axis (GH) and its relationship to dietary restriction and aging +WP4189 Mevalonate arm of cholesterol biosynthesis pathway with inhibitors +WP4190 Mevalonate arm of cholesterol biosynthesis pathway +WP4191 Caloric restriction and aging +WP4194 Hormonal control of Pubertal Growth Spurt +WP4195 Phosphatidylcholine catabolism +WP4197 The human immune response to tuberculosis +WP4204 Tumor suppressor activity of SMARCB1 +WP4205 MET in type 1 papillary renal cell carcinoma +WP4206 Hereditary leiomyomatosis and renal cell carcinoma pathway +WP4210 Tryptophan catabolism leading to NAD+ production +WP4211 Transcriptional cascade regulating adipogenesis +WP4216 Chromosomal and microsatellite instability in colorectal cancer +WP4217 Ebola Virus Pathway on Host +WP422 MAPK Cascade +WP4220 Neurotransmitter Disorders +WP4222 Phosphodiesterases in neuronal function +WP4223 Ras Signaling +WP4224 Purine metabolism and related disorders +WP4225 Pyrimidine metabolism and related diseases +WP4228 Vitamin B6-dependent and responsive disorders +WP4233 Acrylamide Biotransformation and Exposure Biomarkers +WP4236 Disorders of the Krebs cycle +WP4239 Epithelial to mesenchymal transition in colorectal cancer +WP4240 Regulation of sister chromatid separation at the metaphase-anaphase transition +WP4241 Type 2 papillary renal cell carcinoma +WP4249 Hedgehog Signaling Pathway +WP4255 Non-small cell lung cancer +WP4258 LncRNA involvement in canonical Wnt signaling and colorectal cancer +WP4259 Disorders of Folate Metabolism and Transport +WP4262 Breast cancer pathway +WP4263 Pancreatic adenocarcinoma pathway +WP4269 Ethanol metabolism resulting in production of ROS by CYP2E1 +WP4271 Vitamin B12 Disorders +WP428 Wnt Signaling +WP4284 Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer +WP4286 Genotoxicity pathway +WP4288 MTHFR deficiency +WP4290 Metabolic reprogramming in colon cancer +WP4292 Methionine metabolism leading to Sulphur Amino Acids and related disorders +WP4297 Thiamine metabolic pathways +WP4298 Viral Acute Myocarditis +WP4299 Lamin A-processing pathway +WP43 Oxidation by Cytochrome P450 +WP430 Statin Pathway +WP4300 Extracellular vesicles in the crosstalk of cardiac cells +WP4301 Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells +WP4304 Oligodendrocyte Specification and differentiation(including remyelination), leading to Myelin Components for CNS +WP4312 Rett syndrome causing genes +WP4313 Ferroptosis +WP4320 The effect of progerin on the involved genes in Hutchinson-Gilford Progeria Syndrome +WP4321 Thermogenesis +WP4324 Mitochondrial complex I assembly model OXPHOS system +WP4329 miRNAs involvement in the immune response in sepsis +WP4331 Neovascularisation processes +WP4336 ncRNAs involved in Wnt signaling in hepatocellular carcinoma +WP4337 ncRNAs involved in STAT3 signaling in hepatocellular carcinoma +WP4341 Non-genomic actions of 1,25 dihydroxyvitamin D3 +WP4342 Vitamins A and D - action mechanisms +WP4352 Ciliary landscape +WP4357 NRF2-ARE regulation +WP437 EGF/EGFR Signaling Pathway +WP438 Non-homologous end joining +WP4389 Bile Acids synthesis and enterohepatic circulation +WP4396 Nonalcoholic fatty liver disease +WP4397 Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors +WP4399 MicroRNA network associated with chronic lymphocytic leukemia +WP4400 FABP4 in ovarian cancer +WP4404 Interleukin-15 signaling +WP4409 Interleukin-9 signaling +WP4413 Transcriptional Regulation by E2F6 +WP4414 Regulation of RUNX2 expression and activity +WP4415 Transcriptional regulation by RUNX2 +WP4418 Class C/3 (Metabotropic glutamate/pheromone receptors) +WP4419 Class A/1 (Rhodopsin-like receptors) +WP4420 Class B/2 (Secretin family receptors) +WP4421 Signaling by Retinoic Acid +WP4422 G alpha (z) signalling events +WP4423 G alpha (i) signalling events +WP4424 G alpha (q) signalling events +WP4425 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation +WP4426 G alpha (12/13) signalling events +WP4427 G alpha (s) signalling events +WP4428 G-protein beta:gamma signalling +WP4429 NGF processing +WP4430 COPII-mediated vesicle transport +WP4431 Integrin alphaIIb beta3 signaling +WP4432 ESR-mediated signaling +WP4433 TYSND1 cleaves peroxisomal proteins +WP4434 Synthesis of Lipoxins (LX) +WP4435 Serine biosynthesis +WP4436 Signaling by NTRK2 (TRKB) +WP4437 Signaling by PTK6 +WP4438 Biosynthesis of DPA-derived SPMs +WP4439 Biosynthesis of DHA-derived SPMs +WP4440 Biosynthesis of EPA-derived SPMs +WP4441 COPI-mediated anterograde transport +WP4442 Peroxisomal protein import +WP4443 p75 NTR receptor-mediated signalling +WP4444 Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives +WP4445 SUMOylation of transcription cofactors +WP4446 SUMOylation of DNA methylation proteins +WP4447 SUMOylation of intracellular receptors +WP4448 PI3K Cascade +WP4449 SUMOylation of immune response proteins +WP4450 SUMOylation of ubiquitinylation proteins +WP4451 SUMOylation of SUMOylation proteins +WP4452 Signaling by NTRK3 (TRKC) +WP4453 Transcriptional Regulation by MECP2 +WP4454 Acetylcholine binding and downstream events +WP4455 Activation of NMDA receptors and postsynaptic events +WP4456 Activation of kainate receptors upon glutamate binding +WP4457 GABA receptor activation +WP4458 Signaling by Erythropoietin +WP4459 Glutamate binding, activation of AMPA receptors and synaptic plasticity +WP4460 OAS antiviral response +WP4461 DNA Replication Pre-Initiation +WP4462 Platelet-mediated interactions with vascular and circulating cells +WP4478 LTF danger signal response pathway +WP4479 Supression of HMGB1 mediated inflammation by THBD +WP4480 Role of Altered Glycolysation of MUC1 in Tumour Microenvironment +WP4481 Resistin as a regulator of inflammation +WP4482 Vitamin D in inflammatory diseases +WP4483 Relationship between inflammation, COX-2 and EGFR +WP4484 Control of immune tolerance by vasoactive intestinal peptide +WP4485 Modified nucleosides derived from t-RNA as urinary cancer markers +WP4486 Carnosine's role in muscle contraction +WP4487 Ophthalmate biosynthesis in hepatocytes +WP4493 Cells and Molecules involved in local acute inflammatory response +WP4494 Selective expression of chemokine receptors during T-cell polarization +WP4495 IL-10 Anti-inflammatory Signaling Pathway +WP4496 Signal transduction through IL1R +WP45 G1 to S cell cycle control +WP4504 Cysteine and methionine catabolism +WP4506 Tyrosine Metabolism +WP4507 Molybdenum cofactor (Moco) biosynthesis +WP4518 Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases +WP4519 Cerebral Organic Acidurias, including diseases +WP4521 Glycosylation and related congenital defects +WP4522 Metabolic pathway of LDL, HDL and TG, including diseases +WP4523 Classical pathway of steroidogenesis, including diseases +WP4524 The alternative pathway of fetal androgen synthesis +WP453 Inflammatory Response Pathway +WP4532 Intraflagellar transport proteins binding to dynein +WP4533 Transcription co-factors SKI and SKIL protein partners +WP4534 Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms +WP4535 Envelope proteins and their potential roles in EDMD physiopathology +WP4536 Genes related to primary cilium development (based on CRISPR) +WP4537 Hippo-Yap signaling pathway +WP4538 Regulatory circuits of the STAT3 signaling pathway +WP4539 Synaptic signaling pathways associated with autism spectrum disorder +WP4540 Pathways Regulating Hippo Signaling +WP4541 Hippo-Merlin Signaling Dysregulation +WP4542 Overview of leukocyte-intrinsic Hippo pathway functions +WP4545 Oxysterols derived from cholesterol +WP4549 Fragile X Syndrome +WP455 GPCRs, Class A Rhodopsin-like +WP4553 FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma +WP4558 Overview of interferons-mediated signaling pathway +WP4559 Interactions between immune cells and microRNAs in tumor microenvironment +WP4560 MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement +WP4561 Cell migration and invasion through p75NTR +WP4562 Canonical NF-KB pathway +WP4564 Neural Crest Cell Migration during Development +WP4565 Neural Crest Cell Migration in Cancer +WP4566 Translation inhibitors in chronically activated PDGFRA cells +WP4571 Urea cycle and related diseases +WP4577 Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway +WP4580 Blood clotting and drug effects +WP4582 Cancer immunotherapy by CTLA4 blockade +WP4583 Biomarkers for urea cycle disorders +WP4584 Biomarkers for pyrimidine metabolism disorders +WP4585 Cancer immunotherapy by PD-1 blockade +WP4586 Metabolism of alpha-linolenic acid +WP4589 Major receptors targeted by epinephrine and norepinephrine +WP4595 Urea cycle and associated pathways +WP4629 Computational Model of Aerobic Glycolysis +WP465 Tryptophan metabolism +WP4655 Cytosolic DNA-sensing pathway +WP4656 Joubert Syndrome +WP4657 22q11.2 Deletion Syndrome +WP4658 Small cell lung cancer +WP4659 Gastrin Signaling Pathway +WP466 DNA Replication +WP4661 Amino Acid Metabolism Pathway Excerpt (Histidine catabolism extension) +WP4666 Hepatitis B infection +WP4673 Genes involved in male infertility +WP4674 Head and Neck Squamous Cell Carcinoma +WP4685 Melanoma +WP4698 Vitamin D-sensitive calcium signaling in depression +WP47 Hedgehog Signaling Pathway Netpath +WP4705 Pathways of nucleic acid metabolism and innate immune sensing +WP4718 Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways) +WP4719 Eicosanoid metabolism via Cyclo Oxygenases (COX) +WP4720 Eicosanoid metabolism via Cytochrome P450 Mono-Oxygenases (CYP) pathway +WP4721 Eicosanoid metabolism via Lipo Oxygenases (LOX) +WP4722 Glycerolipids and Glycerophospholipids +WP4723 Omega-3/Omega-6 FA synthesis +WP4724 Omega-9 FA synthesis +WP4725 Sphingolipid Metabolism (general overview) +WP4726 Sphingolipid Metabolism (integrated pathway) +WP474 Endochondral Ossification +WP4742 Ketogenesis and Ketolysis +WP4746 Thyroid hormones production and their peripheral downstream signalling effects regarding congenital hypothyroidism +WP4747 Netrin-UNC5B signaling Pathway +WP4751 HIPK2 in kidney fibrosis +WP4752 Base Excision Repair +WP4753 Nucleotide Excision Repair +WP4754 IL-18 signaling pathway +WP4756 Renin Angiotensin Aldosterone System (RAAS) +WP4758 Nephrotic syndrome +WP4760 PKC-gamma calcium signaling pathway in ataxia +WP4767 FGFR3 signalling in chondrocyte proliferation and terminal differentiation +WP477 Cytoplasmic Ribosomal Proteins +WP4784 Proteoglycan biosynthesis +WP4785 Somitogenesis in the context of spondylocostal dysostosis +WP4786 Type I collagen synthesis in the context of Osteogenesis imperfecta +WP4787 Osteoblast differentiation +WP4788 Autosomal recessive Osteopetrosis pathways +WP4789 MED and Pseudoachondroplasia genes +WP4790 FGF23 signalling in Hypophosphatemic rickets +WP4792 Purine metabolism +WP4799 Downregulation of ACE2 expression by SARS-CoV infection and SARS-CoV Spike protein. +WP4803 Ciliopathies +WP4804 Cholesterol Biosynthesis with Skeletal Dysplasias +WP4808 Endochondral Ossification with Skeletal Dysplasias +WP481 Insulin Signaling +WP4814 Somatic Sex determination +WP4815 Glycosaminoglycan degradation +WP4818 Conversion of Angiotensinogen to Angiotensin II +WP4823 Genes controlling renal nephrogenesis +WP4829 mBDNF and proBDNF regulation of GABA neurotransmission +WP4830 GDNF/RET signalling axis +WP4838 Regucalcin in proximal tubule epithelial kidney cells +WP4842 Mammalian disorder of sexual development +WP4846 SARS-CoV-2 and COVID-19 Pathway +WP4853 Linoleic acid metabolism known to be affected by coronavirus infection +WP4856 Intracellular trafficking proteins involved in CMT neuropathy +WP4860 Hijack of Ubiquitination by SARS-CoV-2 +WP4861 Integrative stress response in SARS-CoV-2 infection +WP4862 Autophagy during Corona virus infection +WP4863 Host-pathogen interaction of human corona viruses - autophagy +WP4864 Host-pathogen interaction of human corona viruses - apoptosis +WP4868 Type I Interferon Induction and Signaling During SARS-CoV-2 Infection +WP4869 Host-pathogen interaction of human corona viruses - ER stress +WP4871 Kisspeptin/Kisspeptin Receptor System in the Ovary +WP4872 MAP3K1 role in promoting and blocking gonadal determination +WP4873 Peroxiredoxin 2 induced ovarian failure +WP4875 Disruption of postsynaptic signalling by CNV +WP4876 Activation of NLRP3 Inflammasome by SARS-CoV-2 +WP4877 Host-pathogen interaction of human corona viruses - MAPK signaling +WP4879 Interacting Laminopathic Pathways +WP4880 Host-pathogen interaction of human corona viruses - Interferon induction +WP4883 SARS-CoV-2 and Angiotensin-converting enzyme 2 (ACE2) receptor : Molecular mechanisms and potential therapeutic target +WP4884 Pathogenesis of SARS-CoV-2 Mediated by nsp9/nsp10 Complex +WP4891 COVID-19 AOP +WP49 IL-2 Signaling Pathway +WP4900 Purinergic signaling +WP4904 LDLRAD4 and what we know about it +WP4905 1q21.1 copy number variation syndrome +WP4912 SARS coronavirus and innate immunity +WP4917 Proximal tubule transport +WP4918 Cellular Proteostasis +WP4919 Neuroinflammation +WP4920 Mitochondrial CII Assembly +WP4921 Mitochondrial CIII assembly +WP4922 Mitochondrial CIV Assembly +WP4923 Autophagy +WP4925 Unfolded protein response +WP496 Steroid Biosynthesis +WP497 Urea cycle and metabolism of amino groups +WP500 Glycogen Synthesis and Degradation +WP501 GPCRs, Class C Metabotropic glutamate, pheromone +WP51 Regulation of Actin Cytoskeleton +WP516 Hypertrophy Model +WP521 Amino acid conjugation of benzoic acid +WP524 G13 Signaling Pathway +WP528 Acetylcholine Synthesis +WP53 ID signaling pathway +WP530 Cytokines and Inflammatory Response +WP531 DNA Mismatch Repair +WP534 Glycolysis and Gluconeogenesis +WP536 Calcium Regulation in the Cardiac Cell +WP545 Complement Activation +WP550 Biogenic Amine Synthesis +WP554 ACE Inhibitor Pathway +WP558 Complement and Coagulation Cascades +WP560 TGF-beta Receptor Signaling +WP561 Heme Biosynthesis +WP58 Monoamine GPCRs +WP581 EPO Receptor Signaling +WP585 Interferon type I signaling pathways +WP61 Notch Signaling Pathway Netpath +WP615 Senescence and Autophagy in Cancer +WP619 Type II interferon signaling (IFNG) +WP623 Oxidative phosphorylation +WP661 Glucose Homeostasis +WP673 ErbB Signaling Pathway +WP678 Arachidonate Epoxygenase / Epoxide Hydrolase +WP688 Catalytic cycle of mammalian Flavin-containing MonoOxygenases (FMOs) +WP69 T-Cell antigen Receptor (TCR) Signaling Pathway +WP690 Polyol Pathway +WP691 Tamoxifen metabolism +WP692 Sulfation Biotransformation Reaction +WP694 Arylamine metabolism +WP696 Benzo(a)pyrene metabolism +WP697 Estrogen metabolism +WP698 Glucuronidation +WP699 Aflatoxin B1 metabolism +WP702 Metapathway biotransformation Phase I and II +WP704 Methylation Pathways +WP706 Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways +WP707 DNA Damage Response +WP710 DNA Damage Response (only ATM dependent) +WP712 Estrogen signaling pathway +WP715 Amino acid conjugation +WP716 Vitamin A and Carotenoid Metabolism +WP727 Monoamine Transport +WP732 Serotonin Receptor 2 and ELK-SRF/GATA4 signaling +WP733 Serotonin Receptor 2 and STAT3 Signaling +WP734 Serotonin Receptor 4/6/7 and NR3C Signaling +WP75 Toll-like Receptor Signaling Pathway +WP78 TCA Cycle (aka Krebs or citric acid cycle) +WP80 Nucleotide GPCRs +WP98 Prostaglandin Synthesis and Regulation