From 3355e2c386bfc5de1f6281f150797545c98ac2f1 Mon Sep 17 00:00:00 2001 From: Laura Masa Date: Tue, 9 Jul 2024 17:56:19 +0200 Subject: [PATCH] Add README file --- README.md | 10 +++++++++- 1 file changed, 9 insertions(+), 1 deletion(-) diff --git a/README.md b/README.md index 487063d..b2fa2f6 100644 --- a/README.md +++ b/README.md @@ -1 +1,9 @@ -Work created by Laura Masa +This repository documents the work conducted for my master’s thesis titled "Analyzing Gene Expression Datasets for Disease Annotation Modeling." + +The principal objective of this thesis was to design and implement an automated system for the extraction, processing, and analysis of gene-disease association data. This system was developed to generate a detailed gene-disease annotation model, including gene identifiers, gene expression profiles, and comprehensive metadata. The automation of these processes was intended to provide a structured and efficient platform to support biomedical research efforts and the identification of novel therapeutic targets. + +In addition to the main objective, the thesis aimed to achieve several secondary goals: + +Differential Gene Expression Analysis: To create a Personalized Perturbation Profile (PEEP) that captures gene expression variations for individual and group-level comparisons. +Advancing Personalized Medicine: To leverage PEEP profiles for discovering tailored therapeutic interventions and exploring opportunities for drug repositioning for novel therapeutic applications. +Modeling Disease-Gene Associations: To enhance the semantic understanding and predictive accuracy of gene-disease relationships through advanced modeling techniques. -- 2.24.1