Prompts added

Prompt 1/Prompt 1.txt

+Extract and list all the phenotypic manifestations of the condition found in the “text to analyze”. Classify each extracted term according to its corresponding TUI code and semantic type.
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+                "TUI_Code": "TUI Code 1",
+                "Semantic_Type": "Semantic Type 1"
+            },
+            {
+                "Entity": "Entity Name 2",
+                "TUI_Code": "TUI Code 2",
+                "Semantic_Type": "Semantic Type 2"
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity", "TUI_Code", and "Semantic_Type".

Prompt 1/Prompt 1_guided.txt

+Extract and list the terms found in the “text to analyze” that are phenotypic manifestations of {condition_name}.
+Classify each extracted term according to its corresponding TUI code and Semantic type.
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+                "TUI_Code": "TUI Code 1",
+                "Semantic_Type": "Semantic Type 1"
+            },
+            {
+                "Entity": "Entity Name 2",
+                "TUI_Code": "TUI Code 2",
+                "Semantic_Type": "Semantic Type 2"
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity", "TUI_Code", and "Semantic_Type".

Prompt 2/Prompt 2.txt

+Extract and list all the terms that can be classified into any of the categories in the “TUI code and Semantic type description text” and are related to the condition found in the “text to analyze”. Classify each extracted term into one of the categories in the “TUI code and Semantic type description text.
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+                "TUI_Code": "TUI Code 1",
+                "Semantic_Type": "Semantic Type 1"
+            },
+            {
+                "Entity": "Entity Name 2",
+                "TUI_Code": "TUI Code 2",
+                "Semantic_Type": "Semantic Type 2"
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity", "TUI_Code", and "Semantic_Type".
+
+
+TUI code and Semantic type description text:
+
+1. T019: Congenital Abnormality
+   Description: Abnormal physical or functional conditions present at birth, often due to genetic or developmental factors.
+   Examples:
+   - Cleft lip and palate
+   - Down syndrome (Trisomy 21)
+   - Congenital heart defects
+ 
+2. T020: Acquired Abnormality
+   Description: Abnormal physical or functional conditions that develop after birth, typically as a result of environmental factors, injury, or disease.
+   Examples:
+   - Type 2 diabetes mellitus
+   - Chronic obstructive pulmonary disease (COPD)
+   - Traumatic brain injury
+ 
+3. T033: Finding
+   Description: Observable or measurable manifestations of a condition or disease, including symptoms, signs, and laboratory results.
+   Examples:
+   - Fever (symptom)
+   - Elevated blood pressure (sign)
+   - High blood glucose level (laboratory result)
+ 
+4. T034: Laboratory or Test Result
+   Description: Specific findings obtained through laboratory tests or diagnostic procedures.
+   Examples:
+   - White blood cell count
+   - Serum cholesterol level
+   - Hemoglobin A1c level
+ 
+5. T041: Mental Process
+   Description: Cognitive or psychological activities of the mind, such as perception, reasoning, or memory.
+   Examples:
+   - Decision-making
+   - Problem-solving
+   - Learning
+ 
+6. T046: Pathologic Function
+   Description: Abnormal physiological or biological functions within the body, often associated with disease processes.
+   Examples:
+   - Impaired glucose metabolism
+   - Altered blood flow
+   - Dysregulated immune response
+ 
+7. T047: Disease or Syndrome
+   Description: Pathological conditions characterized by a set of signs, symptoms, or clinical manifestations.
+   Examples:
+   - Hypertension
+   - Diabetes mellitus
+   - Asthma
+ 
+8. T048: Mental or Behavioral Dysfunction
+   Description: Abnormalities or impairments in mental or behavioral functions, such as mood disorders, anxiety, or cognitive deficits.
+   Examples:
+   - Major depressive disorder
+   - Generalized anxiety disorder
+   - Attention-deficit/hyperactivity disorder (ADHD)
+ 
+9. T049: Cell or Molecular Dysfunction
+   Description: Abnormalities or dysfunctions at the cellular or molecular level, including genetic mutations, metabolic disorders, or molecular signaling defects.
+   Examples:
+   - Mutation in the BRCA1 gene (associated with breast cancer)
+   - Deficiency of insulin production in type 1 diabetes mellitus
+   - Dysregulation of neurotransmitter release in Parkinson's disease
+ 
+10. T050: Experimental Model of Disease
+    Description: Experimental models of disease created in laboratory settings to simulate or study specific pathological conditions in biological systems.
+    Examples:
+    - Mouse model of Alzheimer's disease
+    - Zebrafish model of heart failure
+    - Cell culture model of cancer metastasis
+ 
+11. T059: Laboratory Procedure
+    Description: Techniques or methods used in laboratory settings to analyze or study biological specimens, such as blood tests or tissue analyses.
+    Examples:
+    - Polymerase chain reaction (PCR)
+    - Enzyme-linked immunosorbent assay (ELISA)
+    - Western blotting
+ 
+12. T060: Diagnostic Procedure
+    Description: Medical tests or examinations used to identify or confirm the presence of a disease or condition in a patient.
+    Examples:
+    - X-ray imaging
+    - Magnetic resonance imaging (MRI)
+    - Electrocardiogram (ECG)
+ 
+13. T063: Molecular Biology Research Technique
+    Description: Experimental techniques or methods used in molecular biology research, such as polymerase chain reaction (PCR) or gene sequencing.
+    Examples:
+    - CRISPR-Cas9 gene editing
+    - RNA sequencing (RNA-seq)
+    - Chromatin immunoprecipitation (ChIP)
+ 
+14. T073: Manufactured Object
+    Description: Tangible items produced or created through human manufacturing processes, such as medical devices or laboratory equipment.
+    Examples:
+    - Stethoscope
+    - Microscope
+    - Artificial joint prosthesis
+ 
+15. T170: Intellectual Product
+    Description: Abstract or intangible creations of the human intellect, including scientific theories, algorithms, or research findings.
+    Examples:
+    - Newton's laws of motion
+    - Theory of relativity
+    - Computational model of protein folding
+ 
+16. T184: Sign or Symptom
+    Description: Subjective or objective manifestations of a disease or condition experienced or observed by the patient or healthcare provider.
+    Examples:
+    - Headache
+    - Rash
+    - Cough
+ 
+17. T190: Anatomical Abnormality
+    Description: Structural deviations or irregularities in the body's anatomy, including congenital malformations or acquired injuries.
+    Examples:
+    - Spina bifida
+    - Fractured femur
+    - Aortic aneurysm
+ 
+18. T191: Neoplastic Process
+    Description: Abnormal growth or proliferation of cells leading to the formation of tumors or cancerous lesions.
+    Examples:
+    - Breast carcinoma
+    - Lung adenocarcinoma
+    - Melanoma
+ 
+19. T201: Clinical Attribute
+    Description: Characteristics or properties associated with a disease or medical condition, including severity, duration, or response to treatment.
+    Examples:
+    - Severity of pain (mild, moderate, severe)
+    - Duration of symptoms (acute, chronic)
+    - Response to medication (improved, unchanged, worsened)
+

Prompt 2/Prompt 2_guided.txt

+Extract and list all the terms from the “text to analyze” that can be classified into any of the categories in the
+“TUI code and Semantic type description text” and are related to {condition_name}. Classify each extracted 
+term into one of the categories in the “TUI code and Semantic type description text.
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+                "TUI_Code": "TUI Code 1",
+                "Semantic_Type": "Semantic Type 1"
+            },
+            {
+                "Entity": "Entity Name 2",
+                "TUI_Code": "TUI Code 2",
+                "Semantic_Type": "Semantic Type 2"
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity", "TUI_Code", and "Semantic_Type".
+
+
+TUI code and Semantic type description text:
+
+1. T019: Congenital Abnormality
+   Description: Abnormal physical or functional conditions present at birth, often due to genetic or developmental factors.
+   Examples:
+   - Cleft lip and palate
+   - Down syndrome (Trisomy 21)
+   - Congenital heart defects
+ 
+2. T020: Acquired Abnormality
+   Description: Abnormal physical or functional conditions that develop after birth, typically as a result of environmental factors, injury, or disease.
+   Examples:
+   - Type 2 diabetes mellitus
+   - Chronic obstructive pulmonary disease (COPD)
+   - Traumatic brain injury
+ 
+3. T033: Finding
+   Description: Observable or measurable manifestations of a condition or disease, including symptoms, signs, and laboratory results.
+   Examples:
+   - Fever (symptom)
+   - Elevated blood pressure (sign)
+   - High blood glucose level (laboratory result)
+ 
+4. T034: Laboratory or Test Result
+   Description: Specific findings obtained through laboratory tests or diagnostic procedures.
+   Examples:
+   - White blood cell count
+   - Serum cholesterol level
+   - Hemoglobin A1c level
+ 
+5. T041: Mental Process
+   Description: Cognitive or psychological activities of the mind, such as perception, reasoning, or memory.
+   Examples:
+   - Decision-making
+   - Problem-solving
+   - Learning
+ 
+6. T046: Pathologic Function
+   Description: Abnormal physiological or biological functions within the body, often associated with disease processes.
+   Examples:
+   - Impaired glucose metabolism
+   - Altered blood flow
+   - Dysregulated immune response
+ 
+7. T047: Disease or Syndrome
+   Description: Pathological conditions characterized by a set of signs, symptoms, or clinical manifestations.
+   Examples:
+   - Hypertension
+   - Diabetes mellitus
+   - Asthma
+ 
+8. T048: Mental or Behavioral Dysfunction
+   Description: Abnormalities or impairments in mental or behavioral functions, such as mood disorders, anxiety, or cognitive deficits.
+   Examples:
+   - Major depressive disorder
+   - Generalized anxiety disorder
+   - Attention-deficit/hyperactivity disorder (ADHD)
+ 
+9. T049: Cell or Molecular Dysfunction
+   Description: Abnormalities or dysfunctions at the cellular or molecular level, including genetic mutations, metabolic disorders, or molecular signaling defects.
+   Examples:
+   - Mutation in the BRCA1 gene (associated with breast cancer)
+   - Deficiency of insulin production in type 1 diabetes mellitus
+   - Dysregulation of neurotransmitter release in Parkinson's disease
+ 
+10. T050: Experimental Model of Disease
+    Description: Experimental models of disease created in laboratory settings to simulate or study specific pathological conditions in biological systems.
+    Examples:
+    - Mouse model of Alzheimer's disease
+    - Zebrafish model of heart failure
+    - Cell culture model of cancer metastasis
+ 
+11. T059: Laboratory Procedure
+    Description: Techniques or methods used in laboratory settings to analyze or study biological specimens, such as blood tests or tissue analyses.
+    Examples:
+    - Polymerase chain reaction (PCR)
+    - Enzyme-linked immunosorbent assay (ELISA)
+    - Western blotting
+ 
+12. T060: Diagnostic Procedure
+    Description: Medical tests or examinations used to identify or confirm the presence of a disease or condition in a patient.
+    Examples:
+    - X-ray imaging
+    - Magnetic resonance imaging (MRI)
+    - Electrocardiogram (ECG)
+ 
+13. T063: Molecular Biology Research Technique
+    Description: Experimental techniques or methods used in molecular biology research, such as polymerase chain reaction (PCR) or gene sequencing.
+    Examples:
+    - CRISPR-Cas9 gene editing
+    - RNA sequencing (RNA-seq)
+    - Chromatin immunoprecipitation (ChIP)
+ 
+14. T073: Manufactured Object
+    Description: Tangible items produced or created through human manufacturing processes, such as medical devices or laboratory equipment.
+    Examples:
+    - Stethoscope
+    - Microscope
+    - Artificial joint prosthesis
+ 
+15. T170: Intellectual Product
+    Description: Abstract or intangible creations of the human intellect, including scientific theories, algorithms, or research findings.
+    Examples:
+    - Newton's laws of motion
+    - Theory of relativity
+    - Computational model of protein folding
+ 
+16. T184: Sign or Symptom
+    Description: Subjective or objective manifestations of a disease or condition experienced or observed by the patient or healthcare provider.
+    Examples:
+    - Headache
+    - Rash
+    - Cough
+ 
+17. T190: Anatomical Abnormality
+    Description: Structural deviations or irregularities in the body's anatomy, including congenital malformations or acquired injuries.
+    Examples:
+    - Spina bifida
+    - Fractured femur
+    - Aortic aneurysm
+ 
+18. T191: Neoplastic Process
+    Description: Abnormal growth or proliferation of cells leading to the formation of tumors or cancerous lesions.
+    Examples:
+    - Breast carcinoma
+    - Lung adenocarcinoma
+    - Melanoma
+ 
+19. T201: Clinical Attribute
+    Description: Characteristics or properties associated with a disease or medical condition, including severity, duration, or response to treatment.
+    Examples:
+    - Severity of pain (mild, moderate, severe)
+    - Duration of symptoms (acute, chronic)
+    - Response to medication (improved, unchanged, worsened)
+

Prompt 2/Prompt 2_optimizedByChatGPT.txt

+**Task Description**:
+
+Extract and list all terms from the “text to analyze” that can be classified into any of the categories listed in the “TUI code and Semantic type description text.” Classify each extracted term into one of these categories.
+
+**Instructions**:
+
+1. **Extraction**:
+   - Identify and extract all relevant terms from the “text to analyze” that relate to any condition or concept described in the “TUI code and Semantic type description text.”
+   - Ensure that each term directly correlates with one of the provided categories.
+
+2. **Classification**:
+   - For each extracted term, determine the most appropriate category based on the descriptions and examples provided in the “TUI code and Semantic type description text.”
+   - Assign the corresponding TUI code and Semantic Type to each term.
+
+3. **Output Format**:
+   - Present the extracted and classified terms in JSON format.
+   - Ensure that each entity object contains the keys: "Entity", "TUI_Code", and "Semantic_Type."
+
+**Output Structure**:
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+                "TUI_Code": "TUI Code 1",
+                "Semantic_Type": "Semantic Type 1"
+            },
+            {
+                "Entity": "Entity Name 2",
+                "TUI_Code": "TUI Code 2",
+                "Semantic_Type": "Semantic Type 2"
+            }
+        ]
+    }
+]
+
+**Example**:
+
+Given the text to analyze: "Patient exhibits symptoms of fever and high blood glucose level due to Type 2 diabetes mellitus."
+
+- Extracted and classified terms:
+  - "Fever" -> TUI Code: T033, Semantic Type: Finding
+  - "High blood glucose level" -> TUI Code: T034, Semantic Type: Laboratory or Test Result
+  - "Type 2 diabetes mellitus" -> TUI Code: T047, Semantic Type: Disease or Syndrome
+
+**Expected JSON Output**:
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Fever",
+                "TUI_Code": "T033",
+                "Semantic_Type": "Finding"
+            },
+            {
+                "Entity": "High blood glucose level",
+                "TUI_Code": "T034",
+                "Semantic_Type": "Laboratory or Test Result"
+            },
+            {
+                "Entity": "Type 2 diabetes mellitus",
+                "TUI_Code": "T047",
+                "Semantic_Type": "Disease or Syndrome"
+            }
+        ]
+    }
+]
+
+**TUI code and Semantic type description text**:
+
+1. **T019: Congenital Abnormality**
+   - **Description**: Abnormal physical or functional conditions present at birth, often due to genetic or developmental factors.
+   - **Examples**: Cleft lip and palate, Down syndrome (Trisomy 21), Congenital heart defects
+
+2. **T020: Acquired Abnormality**
+   - **Description**: Abnormal physical or functional conditions that develop after birth, typically as a result of environmental factors, injury, or disease.
+   - **Examples**: Type 2 diabetes mellitus, Chronic obstructive pulmonary disease (COPD), Traumatic brain injury
+
+3. **T033: Finding**
+   - **Description**: Observable or measurable manifestations of a condition or disease, including symptoms, signs, and laboratory results.
+   - **Examples**: Fever (symptom), Elevated blood pressure (sign), High blood glucose level (laboratory result)
+
+4. **T034: Laboratory or Test Result**
+   - **Description**: Specific findings obtained through laboratory tests or diagnostic procedures.
+   - **Examples**: White blood cell count, Serum cholesterol level, Hemoglobin A1c level
+
+5. **T041: Mental Process**
+   - **Description**: Cognitive or psychological activities of the mind, such as perception, reasoning, or memory.
+   - **Examples**: Decision-making, Problem-solving, Learning
+
+6. **T046: Pathologic Function**
+   - **Description**: Abnormal physiological or biological functions within the body, often associated with disease processes.
+   - **Examples**: Impaired glucose metabolism, Altered blood flow, Dysregulated immune response
+
+7. **T047: Disease or Syndrome**
+   - **Description**: Pathological conditions characterized by a set of signs, symptoms, or clinical manifestations.
+   - **Examples**: Hypertension, Diabetes mellitus, Asthma
+
+8. **T048: Mental or Behavioral Dysfunction**
+   - **Description**: Abnormalities or impairments in mental or behavioral functions, such as mood disorders, anxiety, or cognitive deficits.
+   - **Examples**: Major depressive disorder, Generalized anxiety disorder, Attention-deficit/hyperactivity disorder (ADHD)
+
+9. **T049: Cell or Molecular Dysfunction**
+   - **Description**: Abnormalities or dysfunctions at the cellular or molecular level, including genetic mutations, metabolic disorders, or molecular signaling defects.
+   - **Examples**: Mutation in the BRCA1 gene (associated with breast cancer), Deficiency of insulin production in type 1 diabetes mellitus, Dysregulation of neurotransmitter release in Parkinson's disease
+
+10. **T050: Experimental Model of Disease**
+    - **Description**: Experimental models of disease created in laboratory settings to simulate or study specific pathological conditions in biological systems.
+    - **Examples**: Mouse model of Alzheimer's disease, Zebrafish model of heart failure, Cell culture model of cancer metastasis
+
+11. **T059: Laboratory Procedure**
+    - **Description**: Techniques or methods used in laboratory settings to analyze or study biological specimens, such as blood tests or tissue analyses.
+    - **Examples**: Polymerase chain reaction (PCR), Enzyme-linked immunosorbent assay (ELISA), Western blotting
+
+12. **T060: Diagnostic Procedure**
+    - **Description**: Medical tests or examinations used to identify or confirm the presence of a disease or condition in a patient.
+    - **Examples**: X-ray imaging, Magnetic resonance imaging (MRI), Electrocardiogram (ECG)
+
+13. **T063: Molecular Biology Research Technique**
+    - **Description**: Experimental techniques or methods used in molecular biology research, such as polymerase chain reaction (PCR) or gene sequencing.
+    - **Examples**: CRISPR-Cas9 gene editing, RNA sequencing (RNA-seq), Chromatin immunoprecipitation (ChIP)
+
+14. **T073: Manufactured Object**
+    - **Description**: Tangible items produced or created through human manufacturing processes, such as medical devices or laboratory equipment.
+    - **Examples**: Stethoscope, Microscope, Artificial joint prosthesis
+
+15. **T170: Intellectual Product**
+    - **Description**: Abstract or intangible creations of the human intellect, including scientific theories, algorithms, or research findings.
+    - **Examples**: Newton's laws of motion, Theory of relativity, Computational model of protein folding
+
+16. **T184: Sign or Symptom**
+    - **Description**: Subjective or objective manifestations of a disease or condition experienced or observed by the patient or healthcare provider.
+    - **Examples**: Headache, Rash, Cough
+
+17. **T190: Anatomical Abnormality**
+    - **Description**: Structural deviations or irregularities in the body's anatomy, including congenital malformations or acquired injuries.
+    - **Examples**: Spina bifida, Fractured femur, Aortic aneurysm
+
+18. **T191: Neoplastic Process**
+    - **Description**: Abnormal growth or proliferation of cells leading to the formation of tumors or cancerous lesions.
+    - **Examples**: Breast carcinoma, Lung adenocarcinoma, Melanoma
+
+19. **T201: Clinical Attribute**
+    - **Description**: Characteristics or properties associated with a disease or medical condition, including severity, duration, or response to treatment.
+    - **Examples**: Severity of pain (mild, moderate, severe), Duration of symptoms (acute, chronic), Response to medication (improved, unchanged, worsened)
+
+**Text to Analyze**:
+

Prompt 2/Prompt 2_simplified.txt

+Extract and list all the terms that can be classified into any of the categories in the “TUI code and Semantic type description text” and are related to the condition found in the “text to analyze”. Classify each extracted term into one of the categories in the “TUI code and Semantic type description text.
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+                "TUI_Code": "TUI Code 1",
+                "Semantic_Type": "Semantic Type 1"
+            },
+            {
+                "Entity": "Entity Name 2",
+                "TUI_Code": "TUI Code 2",
+                "Semantic_Type": "Semantic Type 2"
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity", "TUI_Code", and "Semantic_Type".
+
+
+TUI code and Semantic type description text:
+
+TUI_Code: Semantic_Type
+1. T019: Congenital Abnormality
+2. T020: Acquired Abnormality
+3. T033: Finding
+4. T034: Laboratory or Test Result
+5. T041: Mental Process
+6. T046: Pathologic Function
+7. T047: Disease or Syndrome
+8. T048: Mental or Behavioral Dysfunction
+9. T049: Cell or Molecular Dysfunction
+10. T050: Experimental Model of Disease
+11. T059: Laboratory Procedure
+12. T060: Diagnostic Procedure
+13. T063: Molecular Biology Research Technique
+14. T073: Manufactured Object
+15. T170: Intellectual Product
+16. T184: Sign or Symptom
+17. T190: Anatomical Abnormality
+18. T191: Neoplastic Process
+19. T201: Clinical Attribute

Prompt 2/Prompt 2_simplified_guided.txt

+Extract and list all the terms from the “text to analyze” that can be classified into any of the categories in the
+“TUI code and Semantic type description text” and are related to {condition_name}. Classify each extracted 
+term into one of the categories in the “TUI code and Semantic type description text.
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+                "TUI_Code": "TUI Code 1",
+                "Semantic_Type": "Semantic Type 1"
+            },
+            {
+                "Entity": "Entity Name 2",
+                "TUI_Code": "TUI Code 2",
+                "Semantic_Type": "Semantic Type 2"
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity", "TUI_Code", and "Semantic_Type".
+
+
+TUI code and Semantic type description text:
+
+TUI_Code: Semantic_Type
+1. T019: Congenital Abnormality
+2. T020: Acquired Abnormality
+3. T033: Finding
+4. T034: Laboratory or Test Result
+5. T041: Mental Process
+6. T046: Pathologic Function
+7. T047: Disease or Syndrome
+8. T048: Mental or Behavioral Dysfunction
+9. T049: Cell or Molecular Dysfunction
+10. T050: Experimental Model of Disease
+11. T059: Laboratory Procedure
+12. T060: Diagnostic Procedure
+13. T063: Molecular Biology Research Technique
+14. T073: Manufactured Object
+15. T170: Intellectual Product
+16. T184: Sign or Symptom
+17. T190: Anatomical Abnormality
+18. T191: Neoplastic Process
+19. T201: Clinical Attribute

Prompt 2/Prompt 2_simplified_plusManifestations.txt

+Extract and list all the terms and manifestations that can be classified into any of the categories in the “TUI code and Semantic type description text” and are related to the condition found in the “text to analyze”. Classify each extracted term into one of the categories in the “TUI code and Semantic type description text.
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+                "TUI_Code": "TUI Code 1",
+                "Semantic_Type": "Semantic Type 1"
+            },
+            {
+                "Entity": "Entity Name 2",
+                "TUI_Code": "TUI Code 2",
+                "Semantic_Type": "Semantic Type 2"
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity", "TUI_Code", and "Semantic_Type".
+
+
+TUI code and Semantic type description text:
+
+TUI_Code: Semantic_Type
+1. T019: Congenital Abnormality
+2. T020: Acquired Abnormality
+3. T033: Finding
+4. T034: Laboratory or Test Result
+5. T041: Mental Process
+6. T046: Pathologic Function
+7. T047: Disease or Syndrome
+8. T048: Mental or Behavioral Dysfunction
+9. T049: Cell or Molecular Dysfunction
+10. T050: Experimental Model of Disease
+11. T059: Laboratory Procedure
+12. T060: Diagnostic Procedure
+13. T063: Molecular Biology Research Technique
+14. T073: Manufactured Object
+15. T170: Intellectual Product
+16. T184: Sign or Symptom
+17. T190: Anatomical Abnormality
+18. T191: Neoplastic Process
+19. T201: Clinical Attribute

Prompt 3/Prompt 3.txt

+Extract and list all the terms that can be classified into any of the categories in the “TUI code and Semantic type description text” and are related to the condition found in the “text to analyze”. Classify each extracted term into one of the categories in the “TUI code and Semantic type description text
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+                "TUI_Code": "TUI Code 1",
+                "Semantic_Type": "Semantic Type 1"
+            },
+            {
+                "Entity": "Entity Name 2",
+                "TUI_Code": "TUI Code 2",
+                "Semantic_Type": "Semantic Type 2"
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity", "TUI_Code", and "Semantic_Type".
+
+
+TUI code and Semantic type description text: 
+
+1. T019: Congenital Abnormality
+   Description: Abnormal physical or functional conditions present at birth, often due to genetic or developmental factors.
+   Examples:
+   - Cleft lip and palate
+   - Down syndrome (Trisomy 21)
+   - Congenital heart defects
+ 
+2. T020: Acquired Abnormality
+   Description: Abnormal physical or functional conditions that develop after birth, typically as a result of environmental factors, injury, or disease.
+   Examples:
+   - Type 2 diabetes mellitus
+   - Chronic obstructive pulmonary disease (COPD)
+   - Traumatic brain injury
+ 
+3. T033: Finding
+   Description: Observable or measurable manifestations of a condition or disease, including symptoms, signs, and laboratory results.
+   Examples:
+   - Fever (symptom)
+   - Elevated blood pressure (sign)
+   - High blood glucose level (laboratory result)
+ 
+4. T034: Laboratory or Test Result
+   Description: Specific findings obtained through laboratory tests or diagnostic procedures.
+   Examples:
+   - White blood cell count
+   - Serum cholesterol level
+   - Hemoglobin A1c level
+ 
+5. T041: Mental Process
+   Description: Cognitive or psychological activities of the mind, such as perception, reasoning, or memory.
+   Examples:
+   - Decision-making
+   - Problem-solving
+   - Learning
+ 
+6. T046: Pathologic Function
+   Description: Abnormal physiological or biological functions within the body, often associated with disease processes.
+   Examples:
+   - Impaired glucose metabolism
+   - Altered blood flow
+   - Dysregulated immune response
+ 
+7. T047: Disease or Syndrome
+   Description: Pathological conditions characterized by a set of signs, symptoms, or clinical manifestations.
+   Examples:
+   - Hypertension
+   - Diabetes mellitus
+   - Asthma
+ 
+8. T048: Mental or Behavioral Dysfunction
+   Description: Abnormalities or impairments in mental or behavioral functions, such as mood disorders, anxiety, or cognitive deficits.
+   Examples:
+   - Major depressive disorder
+   - Generalized anxiety disorder
+   - Attention-deficit/hyperactivity disorder (ADHD)
+ 
+9. T049: Cell or Molecular Dysfunction
+   Description: Abnormalities or dysfunctions at the cellular or molecular level, including genetic mutations, metabolic disorders, or molecular signaling defects.
+   Examples:
+   - Mutation in the BRCA1 gene (associated with breast cancer)
+   - Deficiency of insulin production in type 1 diabetes mellitus
+   - Dysregulation of neurotransmitter release in Parkinson's disease
+ 
+10. T050: Experimental Model of Disease
+    Description: Experimental models of disease created in laboratory settings to simulate or study specific pathological conditions in biological systems.
+    Examples:
+    - Mouse model of Alzheimer's disease
+    - Zebrafish model of heart failure
+    - Cell culture model of cancer metastasis
+ 
+11. T059: Laboratory Procedure
+    Description: Techniques or methods used in laboratory settings to analyze or study biological specimens, such as blood tests or tissue analyses.
+    Examples:
+    - Polymerase chain reaction (PCR)
+    - Enzyme-linked immunosorbent assay (ELISA)
+    - Western blotting
+ 
+12. T060: Diagnostic Procedure
+    Description: Medical tests or examinations used to identify or confirm the presence of a disease or condition in a patient.
+    Examples:
+    - X-ray imaging
+    - Magnetic resonance imaging (MRI)
+    - Electrocardiogram (ECG)
+ 
+13. T063: Molecular Biology Research Technique
+    Description: Experimental techniques or methods used in molecular biology research, such as polymerase chain reaction (PCR) or gene sequencing.
+    Examples:
+    - CRISPR-Cas9 gene editing
+    - RNA sequencing (RNA-seq)
+    - Chromatin immunoprecipitation (ChIP)
+ 
+14. T073: Manufactured Object
+    Description: Tangible items produced or created through human manufacturing processes, such as medical devices or laboratory equipment.
+    Examples:
+    - Stethoscope
+    - Microscope
+    - Artificial joint prosthesis
+ 
+15. T170: Intellectual Product
+    Description: Abstract or intangible creations of the human intellect, including scientific theories, algorithms, or research findings.
+    Examples:
+    - Newton's laws of motion
+    - Theory of relativity
+    - Computational model of protein folding
+ 
+16. T184: Sign or Symptom
+    Description: Subjective or objective manifestations of a disease or condition experienced or observed by the patient or healthcare provider.
+    Examples:
+    - Headache
+    - Rash
+    - Cough
+ 
+17. T190: Anatomical Abnormality
+    Description: Structural deviations or irregularities in the body's anatomy, including congenital malformations or acquired injuries.
+    Examples:
+    - Spina bifida
+    - Fractured femur
+    - Aortic aneurysm
+ 
+18. T191: Neoplastic Process
+    Description: Abnormal growth or proliferation of cells leading to the formation of tumors or cancerous lesions.
+    Examples:
+    - Breast carcinoma
+    - Lung adenocarcinoma
+    - Melanoma
+ 
+19. T201: Clinical Attribute
+    Description: Characteristics or properties associated with a disease or medical condition, including severity, duration, or response to treatment.
+    Examples:
+    - Severity of pain (mild, moderate, severe)
+    - Duration of symptoms (acute, chronic)
+    - Response to medication (improved, unchanged, worsened)
+

Prompt 3/Prompt 3_simplified.txt

+Extract and list all the terms that can be classified into any of the categories in the “TUI code and Semantic type description text” and are related to the condition found in the “text to analyze”. Classify each extracted term into one of the categories in the “TUI code and Semantic type description text
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+                "TUI_Code": "TUI Code 1",
+                "Semantic_Type": "Semantic Type 1"
+            },
+            {
+                "Entity": "Entity Name 2",
+                "TUI_Code": "TUI Code 2",
+                "Semantic_Type": "Semantic Type 2"
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity", "TUI_Code", and "Semantic_Type".
+
+
+TUI code and Semantic type description text: 
+
+TUI_Code: Semantic_Type
+1. T019: Congenital Abnormality
+2. T020: Acquired Abnormality
+3. T033: Finding
+4. T034: Laboratory or Test Result
+5. T041: Mental Process
+6. T046: Pathologic Function
+7. T047: Disease or Syndrome
+8. T048: Mental or Behavioral Dysfunction
+9. T049: Cell or Molecular Dysfunction
+10. T050: Experimental Model of Disease
+11. T059: Laboratory Procedure
+12. T060: Diagnostic Procedure
+13. T063: Molecular Biology Research Technique
+14. T073: Manufactured Object
+15. T170: Intellectual Product
+16. T184: Sign or Symptom
+17. T190: Anatomical Abnormality
+18. T191: Neoplastic Process
+19. T201: Clinical Attribute

Prompt 4/Prompt 4.txt

+Extract and list all the terms that can be classified into any of the categories in the “TUI code and Semantic type description text” and are related to the condition found in the “text to analyze”. Classify each extracted term into one of the categories in the “TUI code and Semantic type description text”. Explain why the entity was extracted and why it was classified as such.
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+                "TUI_Code": "TUI Code 1",
+                "Semantic_Type": "Semantic Type 1",
+		"Explanation": "Explanation 1"
+            },
+            {
+                "Entity": "Entity Name 2",
+                "TUI_Code": "TUI Code 2",
+                "Semantic_Type": "Semantic Type 2",
+		"Explanation": "Explanation 2"
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity", "TUI_Code", "Semantic_Type", and "Explanation".
+
+
+TUI code and Semantic type description text: 
+
+1. T019: Congenital Abnormality
+   Description: Abnormal physical or functional conditions present at birth, often due to genetic or developmental factors.
+   Examples:
+   - Cleft lip and palate
+   - Down syndrome (Trisomy 21)
+   - Congenital heart defects
+ 
+2. T020: Acquired Abnormality
+   Description: Abnormal physical or functional conditions that develop after birth, typically as a result of environmental factors, injury, or disease.
+   Examples:
+   - Type 2 diabetes mellitus
+   - Chronic obstructive pulmonary disease (COPD)
+   - Traumatic brain injury
+ 
+3. T033: Finding
+   Description: Observable or measurable manifestations of a condition or disease, including symptoms, signs, and laboratory results.
+   Examples:
+   - Fever (symptom)
+   - Elevated blood pressure (sign)
+   - High blood glucose level (laboratory result)
+ 
+4. T034: Laboratory or Test Result
+   Description: Specific findings obtained through laboratory tests or diagnostic procedures.
+   Examples:
+   - White blood cell count
+   - Serum cholesterol level
+   - Hemoglobin A1c level
+ 
+5. T041: Mental Process
+   Description: Cognitive or psychological activities of the mind, such as perception, reasoning, or memory.
+   Examples:
+   - Decision-making
+   - Problem-solving
+   - Learning
+ 
+6. T046: Pathologic Function
+   Description: Abnormal physiological or biological functions within the body, often associated with disease processes.
+   Examples:
+   - Impaired glucose metabolism
+   - Altered blood flow
+   - Dysregulated immune response
+ 
+7. T047: Disease or Syndrome
+   Description: Pathological conditions characterized by a set of signs, symptoms, or clinical manifestations.
+   Examples:
+   - Hypertension
+   - Diabetes mellitus
+   - Asthma
+ 
+8. T048: Mental or Behavioral Dysfunction
+   Description: Abnormalities or impairments in mental or behavioral functions, such as mood disorders, anxiety, or cognitive deficits.
+   Examples:
+   - Major depressive disorder
+   - Generalized anxiety disorder
+   - Attention-deficit/hyperactivity disorder (ADHD)
+ 
+9. T049: Cell or Molecular Dysfunction
+   Description: Abnormalities or dysfunctions at the cellular or molecular level, including genetic mutations, metabolic disorders, or molecular signaling defects.
+   Examples:
+   - Mutation in the BRCA1 gene (associated with breast cancer)
+   - Deficiency of insulin production in type 1 diabetes mellitus
+   - Dysregulation of neurotransmitter release in Parkinson's disease
+ 
+10. T050: Experimental Model of Disease
+    Description: Experimental models of disease created in laboratory settings to simulate or study specific pathological conditions in biological systems.
+    Examples:
+    - Mouse model of Alzheimer's disease
+    - Zebrafish model of heart failure
+    - Cell culture model of cancer metastasis
+ 
+11. T059: Laboratory Procedure
+    Description: Techniques or methods used in laboratory settings to analyze or study biological specimens, such as blood tests or tissue analyses.
+    Examples:
+    - Polymerase chain reaction (PCR)
+    - Enzyme-linked immunosorbent assay (ELISA)
+    - Western blotting
+ 
+12. T060: Diagnostic Procedure
+    Description: Medical tests or examinations used to identify or confirm the presence of a disease or condition in a patient.
+    Examples:
+    - X-ray imaging
+    - Magnetic resonance imaging (MRI)
+    - Electrocardiogram (ECG)
+ 
+13. T063: Molecular Biology Research Technique
+    Description: Experimental techniques or methods used in molecular biology research, such as polymerase chain reaction (PCR) or gene sequencing.
+    Examples:
+    - CRISPR-Cas9 gene editing
+    - RNA sequencing (RNA-seq)
+    - Chromatin immunoprecipitation (ChIP)
+ 
+14. T073: Manufactured Object
+    Description: Tangible items produced or created through human manufacturing processes, such as medical devices or laboratory equipment.
+    Examples:
+    - Stethoscope
+    - Microscope
+    - Artificial joint prosthesis
+ 
+15. T170: Intellectual Product
+    Description: Abstract or intangible creations of the human intellect, including scientific theories, algorithms, or research findings.
+    Examples:
+    - Newton's laws of motion
+    - Theory of relativity
+    - Computational model of protein folding
+ 
+16. T184: Sign or Symptom
+    Description: Subjective or objective manifestations of a disease or condition experienced or observed by the patient or healthcare provider.
+    Examples:
+    - Headache
+    - Rash
+    - Cough
+ 
+17. T190: Anatomical Abnormality
+    Description: Structural deviations or irregularities in the body's anatomy, including congenital malformations or acquired injuries.
+    Examples:
+    - Spina bifida
+    - Fractured femur
+    - Aortic aneurysm
+ 
+18. T191: Neoplastic Process
+    Description: Abnormal growth or proliferation of cells leading to the formation of tumors or cancerous lesions.
+    Examples:
+    - Breast carcinoma
+    - Lung adenocarcinoma
+    - Melanoma
+ 
+19. T201: Clinical Attribute
+    Description: Characteristics or properties associated with a disease or medical condition, including severity, duration, or response to treatment.
+    Examples:
+    - Severity of pain (mild, moderate, severe)
+    - Duration of symptoms (acute, chronic)
+    - Response to medication (improved, unchanged, worsened)
+

Prompt 4/Prompt 4_simplified.txt

+Extract and list all the terms that can be classified into any of the categories in the “TUI code and Semantic type description text” and are related to the condition found in the “text to analyze”. Classify each extracted term into one of the categories in the “TUI code and Semantic type description text”. Explain why the entity was extracted and why it was classified as such.
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+                "TUI_Code": "TUI Code 1",
+                "Semantic_Type": "Semantic Type 1",
+		"Explanation": "Explanation 1"
+            },
+            {
+                "Entity": "Entity Name 2",
+                "TUI_Code": "TUI Code 2",
+                "Semantic_Type": "Semantic Type 2",
+		"Explanation": "Explanation 2"
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity", "TUI_Code", "Semantic_Type", and "Explanation".
+
+
+TUI code and Semantic type description text: 
+
+TUI_Code: Semantic_Type
+1. T019: Congenital Abnormality
+2. T020: Acquired Abnormality
+3. T033: Finding
+4. T034: Laboratory or Test Result
+5. T041: Mental Process
+6. T046: Pathologic Function
+7. T047: Disease or Syndrome
+8. T048: Mental or Behavioral Dysfunction
+9. T049: Cell or Molecular Dysfunction
+10. T050: Experimental Model of Disease
+11. T059: Laboratory Procedure
+12. T060: Diagnostic Procedure
+13. T063: Molecular Biology Research Technique
+14. T073: Manufactured Object
+15. T170: Intellectual Product
+16. T184: Sign or Symptom
+17. T190: Anatomical Abnormality
+18. T191: Neoplastic Process
+19. T201: Clinical Attribute

Prompt 5/Prompt 5.txt

+Extract and list all the terms that can be classified into any of the categories in the “TUI code and Semantic type description text” and are related to the condition found in the “text to analyze”. Classify each extracted term into one of the categories in the “TUI code and Semantic type description text”. Explain why the entity was extracted and why it was classified as such.
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+                "TUI_Code": "TUI Code 1",
+                "Semantic_Type": "Semantic Type 1",
+		"Explanation": "Explanation 1"
+            },
+            {
+                "Entity": "Entity Name 2",
+                "TUI_Code": "TUI Code 2",
+                "Semantic_Type": "Semantic Type 2",
+		"Explanation": "Explanation 2"
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity", "TUI_Code", "Semantic_Type", and "Explanation".
+
+
+TUI code and Semantic type description text: 
+
+1. T019: Congenital Abnormality
+   Description: Abnormal physical or functional conditions present at birth, often due to genetic or developmental factors.
+   Examples:
+   - Cleft lip and palate
+   - Down syndrome (Trisomy 21)
+   - Congenital heart defects
+ 
+2. T020: Acquired Abnormality
+   Description: Abnormal physical or functional conditions that develop after birth, typically as a result of environmental factors, injury, or disease.
+   Examples:
+   - Type 2 diabetes mellitus
+   - Chronic obstructive pulmonary disease (COPD)
+   - Traumatic brain injury
+ 
+3. T033: Finding
+   Description: Observable or measurable manifestations of a condition or disease, including symptoms, signs, and laboratory results.
+   Examples:
+   - Fever (symptom)
+   - Elevated blood pressure (sign)
+   - High blood glucose level (laboratory result)
+ 
+4. T034: Laboratory or Test Result
+   Description: Specific findings obtained through laboratory tests or diagnostic procedures.
+   Examples:
+   - White blood cell count
+   - Serum cholesterol level
+   - Hemoglobin A1c level
+ 
+5. T041: Mental Process
+   Description: Cognitive or psychological activities of the mind, such as perception, reasoning, or memory.
+   Examples:
+   - Decision-making
+   - Problem-solving
+   - Learning
+ 
+6. T046: Pathologic Function
+   Description: Abnormal physiological or biological functions within the body, often associated with disease processes.
+   Examples:
+   - Impaired glucose metabolism
+   - Altered blood flow
+   - Dysregulated immune response
+ 
+7. T047: Disease or Syndrome
+   Description: Pathological conditions characterized by a set of signs, symptoms, or clinical manifestations.
+   Examples:
+   - Hypertension
+   - Diabetes mellitus
+   - Asthma
+ 
+8. T048: Mental or Behavioral Dysfunction
+   Description: Abnormalities or impairments in mental or behavioral functions, such as mood disorders, anxiety, or cognitive deficits.
+   Examples:
+   - Major depressive disorder
+   - Generalized anxiety disorder
+   - Attention-deficit/hyperactivity disorder (ADHD)
+ 
+9. T049: Cell or Molecular Dysfunction
+   Description: Abnormalities or dysfunctions at the cellular or molecular level, including genetic mutations, metabolic disorders, or molecular signaling defects.
+   Examples:
+   - Mutation in the BRCA1 gene (associated with breast cancer)
+   - Deficiency of insulin production in type 1 diabetes mellitus
+   - Dysregulation of neurotransmitter release in Parkinson's disease
+ 
+10. T050: Experimental Model of Disease
+    Description: Experimental models of disease created in laboratory settings to simulate or study specific pathological conditions in biological systems.
+    Examples:
+    - Mouse model of Alzheimer's disease
+    - Zebrafish model of heart failure
+    - Cell culture model of cancer metastasis
+ 
+11. T059: Laboratory Procedure
+    Description: Techniques or methods used in laboratory settings to analyze or study biological specimens, such as blood tests or tissue analyses.
+    Examples:
+    - Polymerase chain reaction (PCR)
+    - Enzyme-linked immunosorbent assay (ELISA)
+    - Western blotting
+ 
+12. T060: Diagnostic Procedure
+    Description: Medical tests or examinations used to identify or confirm the presence of a disease or condition in a patient.
+    Examples:
+    - X-ray imaging
+    - Magnetic resonance imaging (MRI)
+    - Electrocardiogram (ECG)
+ 
+13. T063: Molecular Biology Research Technique
+    Description: Experimental techniques or methods used in molecular biology research, such as polymerase chain reaction (PCR) or gene sequencing.
+    Examples:
+    - CRISPR-Cas9 gene editing
+    - RNA sequencing (RNA-seq)
+    - Chromatin immunoprecipitation (ChIP)
+ 
+14. T073: Manufactured Object
+    Description: Tangible items produced or created through human manufacturing processes, such as medical devices or laboratory equipment.
+    Examples:
+    - Stethoscope
+    - Microscope
+    - Artificial joint prosthesis
+ 
+15. T170: Intellectual Product
+    Description: Abstract or intangible creations of the human intellect, including scientific theories, algorithms, or research findings.
+    Examples:
+    - Newton's laws of motion
+    - Theory of relativity
+    - Computational model of protein folding
+ 
+16. T184: Sign or Symptom
+    Description: Subjective or objective manifestations of a disease or condition experienced or observed by the patient or healthcare provider.
+    Examples:
+    - Headache
+    - Rash
+    - Cough
+ 
+17. T190: Anatomical Abnormality
+    Description: Structural deviations or irregularities in the body's anatomy, including congenital malformations or acquired injuries.
+    Examples:
+    - Spina bifida
+    - Fractured femur
+    - Aortic aneurysm
+ 
+18. T191: Neoplastic Process
+    Description: Abnormal growth or proliferation of cells leading to the formation of tumors or cancerous lesions.
+    Examples:
+    - Breast carcinoma
+    - Lung adenocarcinoma
+    - Melanoma
+ 
+19. T201: Clinical Attribute
+    Description: Characteristics or properties associated with a disease or medical condition, including severity, duration, or response to treatment.
+    Examples:
+    - Severity of pain (mild, moderate, severe)
+    - Duration of symptoms (acute, chronic)
+    - Response to medication (improved, unchanged, worsened)
+

Prompt 5/Prompt 5_simplified.txt

+Extract and list all the terms that can be classified into any of the categories in the “TUI code and Semantic type description text” and are related to the condition found in the “text to analyze”. Classify each extracted term into one of the categories in the “TUI code and Semantic type description text”. Explain why the entity was extracted and why it was classified as such.
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+                "TUI_Code": "TUI Code 1",
+                "Semantic_Type": "Semantic Type 1",
+		"Explanation": "Explanation 1"
+            },
+            {
+                "Entity": "Entity Name 2",
+                "TUI_Code": "TUI Code 2",
+                "Semantic_Type": "Semantic Type 2",
+		"Explanation": "Explanation 2"
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity", "TUI_Code", "Semantic_Type", and "Explanation".
+
+
+TUI code and Semantic type description text: 
+
+TUI_Code: Semantic_Type
+1. T019: Congenital Abnormality
+2. T020: Acquired Abnormality
+3. T033: Finding
+4. T034: Laboratory or Test Result
+5. T041: Mental Process
+6. T046: Pathologic Function
+7. T047: Disease or Syndrome
+8. T048: Mental or Behavioral Dysfunction
+9. T049: Cell or Molecular Dysfunction
+10. T050: Experimental Model of Disease
+11. T059: Laboratory Procedure
+12. T060: Diagnostic Procedure
+13. T063: Molecular Biology Research Technique
+14. T073: Manufactured Object
+15. T170: Intellectual Product
+16. T184: Sign or Symptom
+17. T190: Anatomical Abnormality
+18. T191: Neoplastic Process
+19. T201: Clinical Attribute

Prompt 6/Prompt 6_PartA.txt

+Extract and list all the terms that are related to the condition found in the “text to analyze”.
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+            },
+            {
+                "Entity": "Entity Name 2",
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity".

Prompt 6/Prompt 6_PartB.txt

+Classify each term of a list of entities according to one of the categories in the “TUI code and Semantic type description text”. If a term cannot be classified into any of the categories in the “TUI code and Semantic type description text”, classify its TUI code and Semantic type as “Other”.
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+                "TUI_Code": "TUI Code 1",
+                "Semantic_Type": "Semantic Type 1"
+            },
+            {
+                "Entity": "Entity Name 2",
+                "TUI_Code": "TUI Code 2",
+                "Semantic_Type": "Semantic Type 2"
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity", "TUI_Code", and "Semantic_Type".
+
+
+TUI code and Semantic type description text: 
+
+1. T019: Congenital Abnormality
+   Description: Abnormal physical or functional conditions present at birth, often due to genetic or developmental factors.
+   Examples:
+   - Cleft lip and palate
+   - Down syndrome (Trisomy 21)
+   - Congenital heart defects
+ 
+2. T020: Acquired Abnormality
+   Description: Abnormal physical or functional conditions that develop after birth, typically as a result of environmental factors, injury, or disease.
+   Examples:
+   - Type 2 diabetes mellitus
+   - Chronic obstructive pulmonary disease (COPD)
+   - Traumatic brain injury
+ 
+3. T033: Finding
+   Description: Observable or measurable manifestations of a condition or disease, including symptoms, signs, and laboratory results.
+   Examples:
+   - Fever (symptom)
+   - Elevated blood pressure (sign)
+   - High blood glucose level (laboratory result)
+ 
+4. T034: Laboratory or Test Result
+   Description: Specific findings obtained through laboratory tests or diagnostic procedures.
+   Examples:
+   - White blood cell count
+   - Serum cholesterol level
+   - Hemoglobin A1c level
+ 
+5. T041: Mental Process
+   Description: Cognitive or psychological activities of the mind, such as perception, reasoning, or memory.
+   Examples:
+   - Decision-making
+   - Problem-solving
+   - Learning
+ 
+6. T046: Pathologic Function
+   Description: Abnormal physiological or biological functions within the body, often associated with disease processes.
+   Examples:
+   - Impaired glucose metabolism
+   - Altered blood flow
+   - Dysregulated immune response
+ 
+7. T047: Disease or Syndrome
+   Description: Pathological conditions characterized by a set of signs, symptoms, or clinical manifestations.
+   Examples:
+   - Hypertension
+   - Diabetes mellitus
+   - Asthma
+ 
+8. T048: Mental or Behavioral Dysfunction
+   Description: Abnormalities or impairments in mental or behavioral functions, such as mood disorders, anxiety, or cognitive deficits.
+   Examples:
+   - Major depressive disorder
+   - Generalized anxiety disorder
+   - Attention-deficit/hyperactivity disorder (ADHD)
+ 
+9. T049: Cell or Molecular Dysfunction
+   Description: Abnormalities or dysfunctions at the cellular or molecular level, including genetic mutations, metabolic disorders, or molecular signaling defects.
+   Examples:
+   - Mutation in the BRCA1 gene (associated with breast cancer)
+   - Deficiency of insulin production in type 1 diabetes mellitus
+   - Dysregulation of neurotransmitter release in Parkinson's disease
+ 
+10. T050: Experimental Model of Disease
+    Description: Experimental models of disease created in laboratory settings to simulate or study specific pathological conditions in biological systems.
+    Examples:
+    - Mouse model of Alzheimer's disease
+    - Zebrafish model of heart failure
+    - Cell culture model of cancer metastasis
+ 
+11. T059: Laboratory Procedure
+    Description: Techniques or methods used in laboratory settings to analyze or study biological specimens, such as blood tests or tissue analyses.
+    Examples:
+    - Polymerase chain reaction (PCR)
+    - Enzyme-linked immunosorbent assay (ELISA)
+    - Western blotting
+ 
+12. T060: Diagnostic Procedure
+    Description: Medical tests or examinations used to identify or confirm the presence of a disease or condition in a patient.
+    Examples:
+    - X-ray imaging
+    - Magnetic resonance imaging (MRI)
+    - Electrocardiogram (ECG)
+ 
+13. T063: Molecular Biology Research Technique
+    Description: Experimental techniques or methods used in molecular biology research, such as polymerase chain reaction (PCR) or gene sequencing.
+    Examples:
+    - CRISPR-Cas9 gene editing
+    - RNA sequencing (RNA-seq)
+    - Chromatin immunoprecipitation (ChIP)
+ 
+14. T073: Manufactured Object
+    Description: Tangible items produced or created through human manufacturing processes, such as medical devices or laboratory equipment.
+    Examples:
+    - Stethoscope
+    - Microscope
+    - Artificial joint prosthesis
+ 
+15. T170: Intellectual Product
+    Description: Abstract or intangible creations of the human intellect, including scientific theories, algorithms, or research findings.
+    Examples:
+    - Newton's laws of motion
+    - Theory of relativity
+    - Computational model of protein folding
+ 
+16. T184: Sign or Symptom
+    Description: Subjective or objective manifestations of a disease or condition experienced or observed by the patient or healthcare provider.
+    Examples:
+    - Headache
+    - Rash
+    - Cough
+ 
+17. T190: Anatomical Abnormality
+    Description: Structural deviations or irregularities in the body's anatomy, including congenital malformations or acquired injuries.
+    Examples:
+    - Spina bifida
+    - Fractured femur
+    - Aortic aneurysm
+ 
+18. T191: Neoplastic Process
+    Description: Abnormal growth or proliferation of cells leading to the formation of tumors or cancerous lesions.
+    Examples:
+    - Breast carcinoma
+    - Lung adenocarcinoma
+    - Melanoma
+ 
+19. T201: Clinical Attribute
+    Description: Characteristics or properties associated with a disease or medical condition, including severity, duration, or response to treatment.
+    Examples:
+    - Severity of pain (mild, moderate, severe)
+    - Duration of symptoms (acute, chronic)
+    - Response to medication (improved, unchanged, worsened)
+

Prompt 6/Prompt 6_simplified_PartA.txt

+Extract and list all the terms that are related to the condition found in the “text to analyze”.
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+            },
+            {
+                "Entity": "Entity Name 2",
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity".

Prompt 6/Prompt 6_simplified_PartB.txt

+Classify each term of a list of entities according to one of the categories in the “TUI code and Semantic type description text”. If a term cannot be classified into any of the categories in the “TUI code and Semantic type description text”, classify its TUI code and Semantic type as “Other”.
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+                "TUI_Code": "TUI Code 1",
+                "Semantic_Type": "Semantic Type 1"
+            },
+            {
+                "Entity": "Entity Name 2",
+                "TUI_Code": "TUI Code 2",
+                "Semantic_Type": "Semantic Type 2"
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity", "TUI_Code", and "Semantic_Type".
+
+
+TUI code and Semantic type description text: 
+
+TUI_Code: Semantic_Type
+1. T019: Congenital Abnormality
+2. T020: Acquired Abnormality
+3. T033: Finding
+4. T034: Laboratory or Test Result
+5. T041: Mental Process
+6. T046: Pathologic Function
+7. T047: Disease or Syndrome
+8. T048: Mental or Behavioral Dysfunction
+9. T049: Cell or Molecular Dysfunction
+10. T050: Experimental Model of Disease
+11. T059: Laboratory Procedure
+12. T060: Diagnostic Procedure
+13. T063: Molecular Biology Research Technique
+14. T073: Manufactured Object
+15. T170: Intellectual Product
+16. T184: Sign or Symptom
+17. T190: Anatomical Abnormality
+18. T191: Neoplastic Process
+19. T201: Clinical Attribute

Prompt 6/Prompt 6_simplified_plusManifestations_PartA.txt

+Extract and list all the terms and manifestations that are related to the condition found in the “text to analyze”.
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+            },
+            {
+                "Entity": "Entity Name 2",
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity".

Prompt 6/Prompt 6_simplified_plusManifestations_PartB.txt

+Classify each term and manifestation of a list according to one of the categories in the “TUI code and Semantic type description text”. If a term cannot be classified into any of the categories in the “TUI code and Semantic type description text”, classify its TUI code and Semantic type as “Other”.
+Format the output as JSON in the following structure:
+
+[
+    {
+        "Entities": [
+            {
+                "Entity": "Entity Name 1",
+                "TUI_Code": "TUI Code 1",
+                "Semantic_Type": "Semantic Type 1"
+            },
+            {
+                "Entity": "Entity Name 2",
+                "TUI_Code": "TUI Code 2",
+                "Semantic_Type": "Semantic Type 2"
+            }
+        ]
+    }
+]
+
+Ensure each object in the "Entities" array contains the keys: "Entity", "TUI_Code", and "Semantic_Type".
+
+
+TUI code and Semantic type description text: 
+
+TUI_Code: Semantic_Type
+1. T019: Congenital Abnormality
+2. T020: Acquired Abnormality
+3. T033: Finding
+4. T034: Laboratory or Test Result
+5. T041: Mental Process
+6. T046: Pathologic Function
+7. T047: Disease or Syndrome
+8. T048: Mental or Behavioral Dysfunction
+9. T049: Cell or Molecular Dysfunction
+10. T050: Experimental Model of Disease
+11. T059: Laboratory Procedure
+12. T060: Diagnostic Procedure
+13. T063: Molecular Biology Research Technique
+14. T073: Manufactured Object
+15. T170: Intellectual Product
+16. T184: Sign or Symptom
+17. T190: Anatomical Abnormality
+18. T191: Neoplastic Process
+19. T201: Clinical Attribute