@@ -35,9 +35,9 @@ Identification of genes that may be potential therapeutic targets depending on w
2. Significantly **correlated** with the genes belonging to its **co-expression module** in different psyhiatric and neurological diseases (PNDs).
3. Part of disease module.
Data regarding the DGE and the co-expression modules were obtained, respectively, from the supplementary material of ... and ...
Data regarding the DGE and the co-expression modules were obtained, respectively, from the supplementary material of [Gandal et al. (2018)](10.1126/science.aad6469) and [Lüscher et al. (2020)](10.1038/s41398-020-0827-5)
## Criteria for identifying drug repurposing candidates:
### Identification of drug repurposing candidates
1. Distance to schizophrenia module between Q1 and median of distance values across treatment drugs.
2. Proximal to disease module (z-score of distance less than or equal to -0.15).