| [Datos_Gppi.csv](https://medal.ctb.upm.es/internal/gitlab/disnet/network-medicine/network-medicine-for-schizophrenia/blob/master/analysis/files/Datos_Gppi.csv) | Protein ID, degree and Average Shortest Path Lenght of each node in the interactome |
| [Microarray_SCZ_metaanalysis_092017.csv](https://medal.ctb.upm.es/internal/gitlab/disnet/network-medicine/network-medicine-for-schizophrenia/blob/master/analysis/files/Microarray_SCZ_metaanalysis_092017.csv) | Results for the meta-analysis on the differential expression of genes in patients with schizophrenia, obtained from the supplementary material of the study of [Gandal et al. (2018)](https://www.science.org/doi/10.1126/science.aad6469) |
| [ Module_signif.csv](https://medal.ctb.upm.es/internal/gitlab/disnet/network-medicine/network-medicine-for-schizophrenia/blob/master/analysis/files/Module_signif.csv) | Number of seed genes, genes in interactome, genes in lcc and results of the statistical validation of the disease module for the pathologies with a significant disease module size |
| [dge_sorted.csv](https://medal.ctb.upm.es/internal/gitlab/disnet/network-medicine/network-medicine-for-schizophrenia/blob/master/analysis/files/dge_sorted.csv) | Genes with significantly higher or lower expression in schizophrenia patients after filtering [Microarray_SCZ_metaanalysis_092017.csv](https://medal.ctb.upm.es/internal/gitlab/disnet/network-medicine/network-medicine-for-schizophrenia/blob/ master/analysis/files/Microarray_SCZ_metaanalysis_092017.csv) file. Sorted by logFC (in absolute value) |
| [ drug_categories.csv ](https://medal.ctb.upm.es/internal/gitlab/disnet/network-medicine/network-medicine-for-schizophrenia/blob/master/analysis/files/drug_categories.csv) | Drug ID and its classification classified regarding the MeSH-pharmacological action (PA) therapeutic uses or its mechanism of action (MOA) |
| [ gandal_2018a_kMEs.csv](https://medal.ctb.upm.es/internal/gitlab/disnet/network-medicine/network-medicine-for-schizophrenia/blob/master/analysis/files/gandal_2018a_kMEs.csv) | Results of the co-expression module membership for each gene in PNDs, obtained from the supplementary material of the study of .[Lüscher et al. (2020)](https://www.nature.com/articles/s41398-020-0827-5). |
Below are the intermediate files that have not been included in this directory due to their large size, as well as the link from which they can be obtained:
| [Closest distance.csv](https://drive.upm.es/s/lGXg33J3Rq0M0oa) | Results for the calculation of the closest distance between each disease - drug pair | https://drive.upm.es/s/lGXg33J3Rq0M0oa |
| [Closest_distance_rand.csv](https://drive.upm.es/s/aUK1BakJsRs6ckB) | Results for the mean and statistical deviation of the closest distance between each disease - drug pair, in comparison with 1,000 disease modules and sets of target proteins of each drug obtained randomly (degree preserving) | https://drive.upm.es/s/aUK1BakJsRs6ckB |
| [SPL PPI.csv](https://drive.upm.es/s/1RhbweyNYLTcCxF) | Shortest Path Length between each pair of proteins in the interactome | https://drive.upm.es/s/1RhbweyNYLTcCxF |
